General information for g4339.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Fatty acid synthase.
Parent gene
- The parent gene g4339 is located on chr_2: 1408006..1409811 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4339 | g4339.t2 | isoform | g4339.t2 | 1408006 | 1409770 |
| chr_2 | g4339 | g4339.t2 | exon | g4339.t2.exon1 | 1408006 | 1409770 |
| chr_2 | g4339 | g4339.t2 | cds | g4339.t2.CDS1 | 1408006 | 1409646 |
| chr_2 | g4339 | g4339.t2 | TSS | g4339.t2 | NA | NA |
| chr_2 | g4339 | g4339.t2 | TTS | g4339.t2 | NA | NA |
Sequences
>g4339.t2 Gene=g4339 Length=1765
TGAAATTTGTACAGCACTTTTCGATAGTTTATACATTCGTTTAGTGTCAAACATTCCAAA
CTCTCAGCGAAAACGATTCCAGAATCGAAAGAAATCACGACGCAAAAATCAAGAAATTTC
AAATATGCCTGCTCGTTTCGAAGATTTAGTAACTGACACAAGACGTAACGCGCCTTCATC
CGTGAACATGGACCTAGACATGAATGAAAGACGCTTTTCACATCAACGTGTCGTTCAAGA
TGATATTTGCATCACTGGCTTCAGTGGGCGCTTGCCTGAGAGTTCAAATATTGATGAATT
CAAACAAAATCTTTTTGATGGTGTCGATATGGTGAATGATGATCCACGTAGATGGGCTGC
TGGTTTGCATGATTTACCAACTCGAACTGGTAAAATTAAGCATGATGATTTGCAAAATTT
AGATGCAGCTTTTTTTAAGCTTCATCAAAAGCAAGCTGAATGTATGGATCCTCAGTTAAG
AATGTTACTCGAATGCACTTATGAAGCCATCATTGATGCCGGTATTAATCCACAAGAAAT
TCGTGGCACTCGCACTGGTGTTTATGTTGGTGTTTCAAACTCTGATAGTGAGGAATTTTG
GTGTCGTGATCCGGATGTTGTTAACGGATATGGACTTACTGGATGTGCACGTTCAATGTT
TGCAAATCGCATTTCTTTTACCTTTGATTTTAAGGGACCAAGTTATGCTGTTGACACTGC
TTGCTCATCATCTCTTTTTGCAATGGATCATGCTTTTCGTGATATAAAGTCTGGTCGAAC
TGATGCAGCAATTGTCGCAGGCGTTGGGTTAATTTTTAAACCAACTATGTCACTTCAATT
TAAACGTCTTAATATGTTGAGTCCAGACGGAATGTGCAAAGCTTTTGATGAGTCTGGAAA
TGGCTATGTCCGATCTGATGGATGTGTTGTAACATTTCTTCAAAAATCAAAAGATTCTCG
TCGTATTTATGCTACTGTATTGAATGTACGCACAAATACTGATGGAGCAAAAGATCAAGG
CATAACATTCCCAAATGGTCAAATGCAAAATCGTTTAATTCGTGAAACTTATGAAGAAAT
TGGTCTTGATCCACGTGAAGTTGTGTATGTTGAAGCTCATGGAACTGGAACAAAAGTTGG
AGACCCCCAAGAAGTAAATTCTATTTGTGACTTTTTCTGCAAAGATCGAAAGACACCATT
GCTGATTGGCAGTGTAAAATCTAATATGGGACATAGTGAGCCAGCATCAGGCGTTTGTTC
AGTAGCAAAAATTCTTATTGCTATGGAAGCTGGAATAATTCCTGGCAATTTGCATTATAA
AAATCCTAATCCAGACCTTTATGGCATAATGGATGGAAGAATGAAAGTTGTTGATAGAAA
TATGGAATGGAATGGAGGCATAATCGGTCTCAATAGTTTTGGATTCGGTGGAGCTAACGC
CCACGTTATATTAAAATCAAATCCTAAGCCAAAAGCAATTGGTTCAATTGGAGAAATTCC
ACGAGTTGTTGCTTGTTCAGGTCGTACAGAAGAAGCTATTAATATGATGTTGAATGAAAT
TGAAGCAAATCGTAATGATGAAGAATTTTTGGGTTTAATAAATGAAATTCATTCAAAGAA
TATTCCTATGCATTACTATCGTGGCTATACTGTCATGGGAGCTGATGGAAGCAATCAACG
TGAAATAGAAGAATGTCGTGATGAAAAACGTCCAATTTGGTATATTTATTCTGGAATGGG
AAGTCAATGGGCAAGTATGGCAAAA
>g4339.t2 Gene=g4339 Length=547
MPARFEDLVTDTRRNAPSSVNMDLDMNERRFSHQRVVQDDICITGFSGRLPESSNIDEFK
QNLFDGVDMVNDDPRRWAAGLHDLPTRTGKIKHDDLQNLDAAFFKLHQKQAECMDPQLRM
LLECTYEAIIDAGINPQEIRGTRTGVYVGVSNSDSEEFWCRDPDVVNGYGLTGCARSMFA
NRISFTFDFKGPSYAVDTACSSSLFAMDHAFRDIKSGRTDAAIVAGVGLIFKPTMSLQFK
RLNMLSPDGMCKAFDESGNGYVRSDGCVVTFLQKSKDSRRIYATVLNVRTNTDGAKDQGI
TFPNGQMQNRLIRETYEEIGLDPREVVYVEAHGTGTKVGDPQEVNSICDFFCKDRKTPLL
IGSVKSNMGHSEPASGVCSVAKILIAMEAGIIPGNLHYKNPNPDLYGIMDGRMKVVDRNM
EWNGGIIGLNSFGFGGANAHVILKSNPKPKAIGSIGEIPRVVACSGRTEEAINMMLNEIE
ANRNDEEFLGLINEIHSKNIPMHYYRGYTVMGADGSNQREIEECRDEKRPIWYIYSGMGS
QWASMAK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g4339.t2 | CDD | cd00833 | PKS | 39 | 443 | 2.49475E-180 |
| 10 | g4339.t2 | Gene3D | G3DSA:3.40.47.10 | - | 36 | 461 | 7.5E-157 |
| 9 | g4339.t2 | Gene3D | G3DSA:3.30.70.3290 | - | 462 | 526 | 3.1E-25 |
| 11 | g4339.t2 | Gene3D | G3DSA:3.40.366.10 | - | 527 | 547 | 3.1E-25 |
| 4 | g4339.t2 | PANTHER | PTHR43775 | FATTY ACID SYNTHASE | 38 | 547 | 1.2E-229 |
| 5 | g4339.t2 | PANTHER | PTHR43775:SF7 | FATTY ACID SYNTHASE | 38 | 547 | 1.2E-229 |
| 2 | g4339.t2 | Pfam | PF00109 | Beta-ketoacyl synthase, N-terminal domain | 39 | 277 | 3.3E-68 |
| 1 | g4339.t2 | Pfam | PF02801 | Beta-ketoacyl synthase, C-terminal domain | 282 | 398 | 3.0E-39 |
| 3 | g4339.t2 | Pfam | PF16197 | Ketoacyl-synthetase C-terminal extension | 401 | 510 | 7.1E-36 |
| 8 | g4339.t2 | ProSitePatterns | PS00606 | Beta-ketoacyl synthases active site. | 191 | 207 | - |
| 7 | g4339.t2 | SMART | SM00825 | Beta-ketoacyl synthase | 41 | 448 | 1.1E-133 |
| 6 | g4339.t2 | SUPERFAMILY | SSF53901 | Thiolase-like | 38 | 445 | 1.36E-73 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016746 | acyltransferase activity | MF |
| GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity | MF |
| GO:0016740 | transferase activity | MF |
| GO:0006633 | fatty acid biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K12437 (polyketide synthase 13)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed