General information for g4405.t31
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Putative cysteine proteinase CG12163.
Parent gene
- The parent gene g4405 is located on chr_2: 2005157..2008641 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4405 | g4405.t31 | isoform | g4405.t31 | 2002236 | 2005157 |
| chr_2 | g4405 | g4405.t31 | exon | g4405.t31.exon1 | 2002236 | 2002970 |
| chr_2 | g4405 | g4405.t31 | cds | g4405.t31.CDS1 | 2002237 | 2002970 |
| chr_2 | g4405 | g4405.t31 | exon | g4405.t31.exon2 | 2003043 | 2003089 |
| chr_2 | g4405 | g4405.t31 | cds | g4405.t31.CDS2 | 2003043 | 2003089 |
| chr_2 | g4405 | g4405.t31 | exon | g4405.t31.exon3 | 2003160 | 2003281 |
| chr_2 | g4405 | g4405.t31 | cds | g4405.t31.CDS3 | 2003160 | 2003281 |
| chr_2 | g4405 | g4405.t31 | exon | g4405.t31.exon4 | 2005077 | 2005157 |
| chr_2 | g4405 | g4405.t31 | cds | g4405.t31.CDS4 | 2005077 | 2005157 |
| chr_2 | g4405 | g4405.t31 | TSS | g4405.t31 | 2005223 | 2005223 |
| chr_2 | g4405 | g4405.t31 | TTS | g4405.t31 | NA | NA |
Sequences
>g4405.t31 Gene=g4405 Length=985
ATGTGGAAATTTAAAATTTTGCTAATTTGTTTAGCAAGTATTATAATAGTTAATGCCACA
GAATGTGAAGATTGTCAAAATCGTGCTGCTCGTCAAATCGGTGTTCCCGGTGGAATCAGT
CCTGTAGAAAACTTTGAAGATGTAAAAATTTATGTTCAAGAAGCTATTGATGAAATTAAT
GATAATGAAGATCCTGATTACATTTTGAAACATATCGTTGAAGCAACCCAACAAGTTGTT
GCAGGCATGACTTGGATTAAAGATGGACGTAAAGTTTCAGTTTCTTGCAAAAATGATAAG
AAATATAAGTTGACCCAATCACCATCTAATCAGCGTGTCAAACGTGATAACACGCTTGAA
AGAGTTCTTGGTTTACCATCCAATACTGATGATCATGACGATTTGATAAAAATACTTTCT
GAACATTTGAAGAGACTCGATACTGGAAGTGATGCACAATTTGAATTGGTAAAACTTGAA
AAGGTAACTCAACAAGTAGTAGCTGGAATAAAATATAAAGCAACAGGTATTTTTAAAATT
GGCAATGAAGAGAAAAAATGTGTTATCGATGTATGGCATCGCTCATGGATTAAGGGAGAT
GAAGGCACTCAATTAAGCGCTGATTGTGATAAAGGTGCAACAACTTTCAAGACAAAATCT
TCTAGAAAAAGGAGATCAGTTCATCACCACACACACAATCGTCACAATAGACAATCAGTA
AGCGATCATTTTGATGACCATCATCATCATACTGATAGACATCATCATCAATACTCAGCT
ACTGAAGAAATGAAAGAAATAAAATCTGAAATTTTATTTAACAATTTCATAACTAAATAT
AATCGTAAATATGCCAATGAACTTGAACATAAAATGAGAATGAGAATTTTCAAGAAGAAT
TTACATAAAATTGAAATGTTGAATAAGCATGAACAAGGCACTGCAAAGTATGGAATTACA
GAATTCGCTGATTTAACTGAAAAGG
>g4405.t31 Gene=g4405 Length=328
MWKFKILLICLASIIIVNATECEDCQNRAARQIGVPGGISPVENFEDVKIYVQEAIDEIN
DNEDPDYILKHIVEATQQVVAGMTWIKDGRKVSVSCKNDKKYKLTQSPSNQRVKRDNTLE
RVLGLPSNTDDHDDLIKILSEHLKRLDTGSDAQFELVKLEKVTQQVVAGIKYKATGIFKI
GNEEKKCVIDVWHRSWIKGDEGTQLSADCDKGATTFKTKSSRKRRSVHHHTHNRHNRQSV
SDHFDDHHHHTDRHHHQYSATEEMKEIKSEILFNNFITKYNRKYANELEHKMRMRIFKKN
LHKIEMLNKHEQGTAKYGITEFADLTEK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g4405.t31 | Gene3D | G3DSA:3.10.450.10 | - | 31 | 107 | 6.4E-8 |
| 7 | g4405.t31 | Gene3D | G3DSA:3.10.450.10 | - | 118 | 208 | 3.3E-11 |
| 8 | g4405.t31 | Gene3D | G3DSA:3.90.70.10 | Cysteine proteinases | 254 | 328 | 3.0E-11 |
| 16 | g4405.t31 | MobiDBLite | mobidb-lite | consensus disorder prediction | 215 | 261 | - |
| 18 | g4405.t31 | MobiDBLite | mobidb-lite | consensus disorder prediction | 218 | 236 | - |
| 17 | g4405.t31 | MobiDBLite | mobidb-lite | consensus disorder prediction | 237 | 261 | - |
| 1 | g4405.t31 | Pfam | PF08246 | Cathepsin propeptide inhibitor domain (I29) | 273 | 327 | 1.5E-11 |
| 10 | g4405.t31 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 22 | - |
| 11 | g4405.t31 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 5 | - |
| 12 | g4405.t31 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 6 | 17 | - |
| 13 | g4405.t31 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 18 | 22 | - |
| 9 | g4405.t31 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 23 | 328 | - |
| 15 | g4405.t31 | SMART | SM00848 | Inhibitor_I29_2 | 273 | 328 | 3.8E-12 |
| 2 | g4405.t31 | SUPERFAMILY | SSF54403 | Cystatin/monellin | 32 | 85 | 6.56E-7 |
| 3 | g4405.t31 | SUPERFAMILY | SSF54403 | Cystatin/monellin | 131 | 198 | 2.13E-8 |
| 4 | g4405.t31 | SUPERFAMILY | SSF54001 | Cysteine proteinases | 266 | 327 | 2.55E-11 |
| 5 | g4405.t31 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
| 14 | g4405.t31 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed