Gene loci information

Transcript annotation

  • This transcript has been annotated as Exportin-1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g4524 g4524.t1 TTS g4524.t1 3054077 3054077
chr_2 g4524 g4524.t1 isoform g4524.t1 3054352 3057814
chr_2 g4524 g4524.t1 exon g4524.t1.exon1 3054352 3054501
chr_2 g4524 g4524.t1 cds g4524.t1.CDS1 3054352 3054501
chr_2 g4524 g4524.t1 exon g4524.t1.exon2 3054563 3054928
chr_2 g4524 g4524.t1 cds g4524.t1.CDS2 3054563 3054928
chr_2 g4524 g4524.t1 exon g4524.t1.exon3 3054993 3055325
chr_2 g4524 g4524.t1 cds g4524.t1.CDS3 3054993 3055325
chr_2 g4524 g4524.t1 exon g4524.t1.exon4 3055385 3055762
chr_2 g4524 g4524.t1 cds g4524.t1.CDS4 3055385 3055762
chr_2 g4524 g4524.t1 exon g4524.t1.exon5 3055822 3056361
chr_2 g4524 g4524.t1 cds g4524.t1.CDS5 3055822 3056361
chr_2 g4524 g4524.t1 exon g4524.t1.exon6 3056417 3057814
chr_2 g4524 g4524.t1 cds g4524.t1.CDS6 3056417 3057814
chr_2 g4524 g4524.t1 TSS g4524.t1 3058761 3058761

Sequences

>g4524.t1 Gene=g4524 Length=3165
ATGGCGACGTTACGAATGGAAGAAGCATCTCGATTACTCGATTTTTCGCAAAAGCTGGAT
ATTTCTTTATTAGAGAATATTGTCGGATGCTTATACAATAGTCAGGGTGAACAATTAAGA
TTAGCTCAAGAAATTCTGACTACACTGAAAGAACATCCCGATGCATGGACGCGTGTTGAT
ACAATTTTAGAGTTCAGTGAAAATCAACAAACAAAATATTATGCCCTTCAAATTCTTGAA
GAAGTAATCAAAACACGCTGGAAAGTTTTACCAAGAAATCAATGTGAAGGCATAAAGAAA
TACGTAGTCGGACTTATTATAAAAACATCGTCTGATCCAAAAGTTATGGAAACAAATAAA
GTCTATCTTAATAAGTTGAACATTATTTTAGTTCAGATTCTAAAACGTGAATGGCCCAAA
AATTGGGAGACCTTCATAAGCGATATAGTTGGTGCATCAAAGACAAATGAAACACTTTGT
CAAAACAACATGATCATTTTAAAATTACTGAGTGAAGAGGTGTTTGATTTCTCGAGTGGA
CAAATTACACAAACTAAAGCAAAGCATCTAAAAGATACGATGTGCTCTGAATTTTCTCAA
GTTTTTCAACTCTGTTCGTTTGTTTTGGAAAATTCATTGAATGCACCACTCATCAGCGCT
ACTCTTGAAACTTTGTTAAAATTTCTCAATTGGATTCCGCTTGGTTATATTTTTGAGACT
AAACTCATCAATATGCTTGTTGAAAAGTTCTTGGTTATCCCAATGTTTCGTAATGTAACG
CTAAAATGTTTGTCTGAAATTGCTGGCCTTCAATTGCAAAATTACGATCATATTTTTATA
CAGTTGTTTGTACAAACGATGGAGCAGTTTGTTCAAATGATTCCTGCCGATACAAATATG
AATCAAATCTATGCAAATGGCAACGATGAAGAGCAGTGTTTTGTGCAAAATTTAGCCATG
TTCTTATGCACATTTTTACGAGTACATGCAACATTGGTAGAAAAACGAGAAACTGCTGAT
GCCGTGAATAAAGCGTTAATATATCTGGTAATGATCAGTGAAGTGGAAGATGTTGAACTG
TTTAAAATTTGTTTAGAATATTGGAACAGTTTAACTGCTGATTTGTACAAAGAAAATCCT
TATGGTCAATCATCGGGCTCTCGACGTCAATTTTATTCAAACATCTTATCAAAAGTTCGT
AACATCATGATTTCTCGCATGGCCAAACCAGAGGAAGTGCTTGTCGTTGAAAATGAAAAT
GGGGAGGTAGTTCGTGAATTTATGAAGGACACAAACAGTATCAATTTGTACAAGAATATG
AGAGAAACTTTGGTCTATTTAACGCATTTGGATTACTTTGATACCGAACGCATTATGACT
GAGAAATTGAATAAACAAGTAAATGGGACAGAATTTTCTTGGAAAAATTTAAATACGTTA
TGTTGGGCCATTGGATCAATTTCTGGCGCCTTTTATGAAGAAGATGAAAAGAGATTTTTG
GTTGCTGTAATTAAAGATTTATTGGGTTTGTGTGAACAGAAGAAAGGAAAAGATAATAAG
GCTATTATTGCAAGTAATATCATGTATGTTGTGGGTCAATATCCACGATTTTTGAGAGCT
CATTGGAAATTTTTAAAAACCGTTGTCAATAAGCTATTTGAATTTATGCATGAAACTCAT
GATGGTGTACAAGATATGGCATGCGATACATTCATTAAGATTGCAATGAAGTGTAAACGA
CATTTTGTAACAATGCAACCAAATGAAGGATGCACTTTTGTAGAGGAAATTCTTACTAAT
ACGAGTACAATAATTTGCGATCTGCAACCACAGCAAGTTCATACATTTTATGAAGCTGTT
GGATACATGATAAGTGCTCAGGTCGATCAAGTACAACAAGATGGGCTTATAAAGAAATAT
ATGAGTTTGCCAAATGAGGTTTGGGATCGTATAATAAATCATGCTGCTGAAAATGCAGAT
ATCCTCAAAGATATGGCAGCTGTGAAGCAAATTGGGAGCATTTTAAAAACTAACGTGCGC
GCCTGTAAAGCACTTGGACACAATTATGTTATTCAATTGGGATGTATTTACCTCGATATG
TTAAACGTTTATAAAATTATGTCTGAAAACATCTCTCAGGCGATTTCACTTAATGGTATT
GCAATTAATAATCAGCCGCTAATAAAAGCAATGCATGTAGTGAAAAAGGAAACATTAACA
TTGATTAGTGAGTGGATTATAAGATCGAATGACCCTCAGATGGTCATGGAAAGTTTCATA
CCACCTCTTCTCGACGCTGTTTTGCTAGATTATCAGCGTACTATCGTTCCATCTGCGCGT
GAACCAACTGTTCTAAGTACAATGGCGGCAATTGTAAACAAACTTGAAGGCGTCATAACG
AGTGAAGTTCCGAAAATTTTCGATGCTGTATTTGAATGTACTCTTGACATGATTAACAAA
AACTTTGAAGACTATCCTCAACATCGAACTTATTTCTATGAATTGTTACAAGCAGTAAAT
CTACACTGCTTTAAAGCATTCTTAAACATCCCTCCCACGCAATTCAAATTGGTTTTCGAT
TCTATTGTATGGGCATTCAAACACACAATGCGAAATGTTGCGGACACAGGATTATCAATT
TTGTTCCAACTTTTGCAAAATCTCGAGCAACACCCACAAGCAGCACAGAGTTTTTATCAA
ACCTACTTTACTGATATCCTTATGCAAATCTTTAGCGTCGTTACGGATACATCGCACACA
GCATCGCTCCAATCTCATGCTCAAATTCTCGCCCATATGTTCTCTTTAGTTGAAGCAAAT
GCGATAACAGTTCCGCTTGGACCAATTCCAAATAACGTTCTCTATATTCAGGAATATGTT
GCTTCACTTCTGAAATCTGCATTTGGACATTTGACCGATAATCAAATAAAAGTTTTCGTT
ACTGGACTTTTTAATTTAGATCACGATGTGGCACAGTTCAAAGAACATTTGCGAGATTTC
ATTATTCAAATTCGAGAAGTAACTGGTGATGATGATTCAGATCTCTATCTAGAAGAGCGA
GAACAAGAACTAAAGAAAGCACAAGAAGAAAAACGTCGTCATCAGTTGACTGTGCCTGGT
ATGCTTAATCCGCATGAACTTCCGGAAGACATGCAGGACGAATAA

>g4524.t1 Gene=g4524 Length=1054
MATLRMEEASRLLDFSQKLDISLLENIVGCLYNSQGEQLRLAQEILTTLKEHPDAWTRVD
TILEFSENQQTKYYALQILEEVIKTRWKVLPRNQCEGIKKYVVGLIIKTSSDPKVMETNK
VYLNKLNIILVQILKREWPKNWETFISDIVGASKTNETLCQNNMIILKLLSEEVFDFSSG
QITQTKAKHLKDTMCSEFSQVFQLCSFVLENSLNAPLISATLETLLKFLNWIPLGYIFET
KLINMLVEKFLVIPMFRNVTLKCLSEIAGLQLQNYDHIFIQLFVQTMEQFVQMIPADTNM
NQIYANGNDEEQCFVQNLAMFLCTFLRVHATLVEKRETADAVNKALIYLVMISEVEDVEL
FKICLEYWNSLTADLYKENPYGQSSGSRRQFYSNILSKVRNIMISRMAKPEEVLVVENEN
GEVVREFMKDTNSINLYKNMRETLVYLTHLDYFDTERIMTEKLNKQVNGTEFSWKNLNTL
CWAIGSISGAFYEEDEKRFLVAVIKDLLGLCEQKKGKDNKAIIASNIMYVVGQYPRFLRA
HWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAMKCKRHFVTMQPNEGCTFVEEILTN
TSTIICDLQPQQVHTFYEAVGYMISAQVDQVQQDGLIKKYMSLPNEVWDRIINHAAENAD
ILKDMAAVKQIGSILKTNVRACKALGHNYVIQLGCIYLDMLNVYKIMSENISQAISLNGI
AINNQPLIKAMHVVKKETLTLISEWIIRSNDPQMVMESFIPPLLDAVLLDYQRTIVPSAR
EPTVLSTMAAIVNKLEGVITSEVPKIFDAVFECTLDMINKNFEDYPQHRTYFYELLQAVN
LHCFKAFLNIPPTQFKLVFDSIVWAFKHTMRNVADTGLSILFQLLQNLEQHPQAAQSFYQ
TYFTDILMQIFSVVTDTSHTASLQSHAQILAHMFSLVEANAITVPLGPIPNNVLYIQEYV
ASLLKSAFGHLTDNQIKVFVTGLFNLDHDVAQFKEHLRDFIIQIREVTGDDDSDLYLEER
EQELKKAQEEKRRHQLTVPGMLNPHELPEDMQDE

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g4524.t1 Coils Coil Coil 1017 1037 -
10 g4524.t1 Gene3D G3DSA:1.25.10.10 - 1 1037 0.0
14 g4524.t1 MobiDBLite mobidb-lite consensus disorder prediction 1026 1054 -
7 g4524.t1 PANTHER PTHR11223:SF4 EXPORTIN 1 (CRM1 HOMOLOG, YEAST) B 8 1053 0.0
8 g4524.t1 PANTHER PTHR11223 EXPORTIN 1/5 8 1053 0.0
3 g4524.t1 Pfam PF03810 Importin-beta N-terminal domain 42 107 4.6E-11
6 g4524.t1 Pfam PF08389 Exportin 1-like protein 120 264 6.1E-40
1 g4524.t1 Pfam PF18777 Chromosome region maintenance or exportin repeat 341 376 5.9E-18
5 g4524.t1 Pfam PF18784 CRM1 / Exportin repeat 2 388 455 6.4E-36
4 g4524.t1 Pfam PF18787 CRM1 / Exportin repeat 3 468 518 1.9E-27
2 g4524.t1 Pfam PF08767 CRM1 C terminal 692 1008 8.6E-125
15 g4524.t1 ProSiteProfiles PS50166 Importin-beta N-terminal domain profile. 42 108 14.122
13 g4524.t1 SMART SM00913 IBN_N_2 42 108 1.6E-10
12 g4524.t1 SMART SM01102 CRM1_C_2 692 1009 1.0E-185
9 g4524.t1 SUPERFAMILY SSF48371 ARM repeat 24 1014 6.64E-115

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0031267 small GTPase binding MF
GO:0006886 intracellular protein transport BP
GO:0005049 nuclear export signal receptor activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values