General information for g4781.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit beta type-7.
Parent gene
- The parent gene g4781 is located on chr_2: 4944008..4944662 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4781 | g4781.t1 | TSS | g4781.t1 | 4943648 | 4943648 |
| chr_2 | g4781 | g4781.t1 | isoform | g4781.t1 | 4943699 | 4944662 |
| chr_2 | g4781 | g4781.t1 | exon | g4781.t1.exon1 | 4943699 | 4943760 |
| chr_2 | g4781 | g4781.t1 | cds | g4781.t1.CDS1 | 4943699 | 4943760 |
| chr_2 | g4781 | g4781.t1 | exon | g4781.t1.exon2 | 4943814 | 4943911 |
| chr_2 | g4781 | g4781.t1 | cds | g4781.t1.CDS2 | 4943814 | 4943911 |
| chr_2 | g4781 | g4781.t1 | exon | g4781.t1.exon3 | 4943998 | 4944662 |
| chr_2 | g4781 | g4781.t1 | cds | g4781.t1.CDS3 | 4943998 | 4944662 |
| chr_2 | g4781 | g4781.t1 | TTS | g4781.t1 | 4944681 | 4944681 |
Sequences
>g4781.t1 Gene=g4781 Length=825
ATGTTGAATAATTTTGCTACTTTGGATGAAGAAAGAGGATTTAGTTTTAGAAATTGTAAA
AGAAATGCTCAATTAGTTGCAAATGGTTTTATTCCTCCAAAAGCGATTAAAACTGGTACG
ACAATCTGCGGTGTCACTTATAAAGATGGTGTTGTTTTAGGTTGTGACACAAGAACAACA
ATTGGCAACATCATTTGGGAGAAAAAATGTGAGAAAATTTATAAAATTCAGAATAATATT
TTTGTAGCAGGAGCTGGAACCGCTGCTGATATGGATGGAATGGTTAAATGGATGCGCAGT
AATATGGAATTGCATAGATTAAATACTAATAGAAAAATAGTTCCAGTTATTACATTAGTG
ACAACTTTAAGTCATCATTTCTTTAGATATGGCGGTGCAATTTCTTGTGTCTTTTTAATA
GGCGGTGTTGACAATAATGGACCACATTTGCATGTTGTTTATAAACATGGCTCAAAAATG
AAACTACCTTATGCTACAATGGGTTCTGGTTCTTATGCAGCGATGACAATTCTTGAAACT
CGTTGGAAACCAGATATGACTGAGCAGGAAGCTAAAGAATTAGTTGCAGATGCAATCACA
TCTGGTGTTGTTAATGACTTGGGTTCAGGGACAAATGTTAATTTATGTGTCATTAGAAAG
AGCTCATCTGAAAAAATTAATGGCTATAGAGAAATTTGTGGAAATGGAAAAAGAATTCTT
GATTACTCTATAAAACATGGCACAACTGGCATAATATCAGAAACAATTAAAAAGATTGAA
TTGGATGTTATTGAAGAGCAGATTGAAAAAATGGAAGTTGAATAA
>g4781.t1 Gene=g4781 Length=274
MLNNFATLDEERGFSFRNCKRNAQLVANGFIPPKAIKTGTTICGVTYKDGVVLGCDTRTT
IGNIIWEKKCEKIYKIQNNIFVAGAGTAADMDGMVKWMRSNMELHRLNTNRKIVPVITLV
TTLSHHFFRYGGAISCVFLIGGVDNNGPHLHVVYKHGSKMKLPYATMGSGSYAAMTILET
RWKPDMTEQEAKELVADAITSGVVNDLGSGTNVNLCVIRKSSSEKINGYREICGNGKRIL
DYSIKHGTTGIISETIKKIELDVIEEQIEKMEVE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g4781.t1 | CDD | cd03763 | proteasome_beta_type_7 | 40 | 229 | 9.42674E-99 |
| 10 | g4781.t1 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 40 | 274 | 5.5E-71 |
| 3 | g4781.t1 | PANTHER | PTHR11599:SF42 | PROTEASOME SUBUNIT BETA TYPE-7 | 20 | 262 | 1.1E-71 |
| 4 | g4781.t1 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 20 | 262 | 1.1E-71 |
| 5 | g4781.t1 | PRINTS | PR00141 | Proteasome component signature | 47 | 62 | 7.2E-8 |
| 6 | g4781.t1 | PRINTS | PR00141 | Proteasome component signature | 168 | 179 | 7.2E-8 |
| 7 | g4781.t1 | PRINTS | PR00141 | Proteasome component signature | 179 | 190 | 7.2E-8 |
| 8 | g4781.t1 | PRINTS | PR00141 | Proteasome component signature | 204 | 215 | 7.2E-8 |
| 1 | g4781.t1 | Pfam | PF00227 | Proteasome subunit | 36 | 218 | 1.9E-48 |
| 2 | g4781.t1 | Pfam | PF12465 | Proteasome beta subunits C terminal | 236 | 267 | 2.7E-6 |
| 12 | g4781.t1 | ProSitePatterns | PS00854 | Proteasome beta-type subunits signature. | 43 | 90 | - |
| 13 | g4781.t1 | ProSiteProfiles | PS51476 | Proteasome beta-type subunit profile. | 39 | 218 | 39.356 |
| 9 | g4781.t1 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 12 | 228 | 3.26E-59 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0004298 | threonine-type endopeptidase activity | MF |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02739 (20S proteasome subunit beta 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed