General information for g5057.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Disintegrin and metalloproteinase domain-containing protein 10.
Parent gene
- The parent gene g5057 is located on chr_2: 6638513..6639971 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g5057 | g5057.t2 | isoform | g5057.t2 | 6635490 | 6639377 |
| chr_2 | g5057 | g5057.t2 | exon | g5057.t2.exon1 | 6635490 | 6636095 |
| chr_2 | g5057 | g5057.t2 | cds | g5057.t2.CDS1 | 6635490 | 6636095 |
| chr_2 | g5057 | g5057.t2 | exon | g5057.t2.exon2 | 6636198 | 6636391 |
| chr_2 | g5057 | g5057.t2 | cds | g5057.t2.CDS2 | 6636198 | 6636391 |
| chr_2 | g5057 | g5057.t2 | exon | g5057.t2.exon3 | 6636702 | 6636719 |
| chr_2 | g5057 | g5057.t2 | cds | g5057.t2.CDS3 | 6636702 | 6636719 |
| chr_2 | g5057 | g5057.t2 | exon | g5057.t2.exon4 | 6639311 | 6639377 |
| chr_2 | g5057 | g5057.t2 | cds | g5057.t2.CDS4 | 6639311 | 6639377 |
| chr_2 | g5057 | g5057.t2 | TSS | g5057.t2 | 6639965 | 6639965 |
| chr_2 | g5057 | g5057.t2 | TTS | g5057.t2 | NA | NA |
Sequences
>g5057.t2 Gene=g5057 Length=885
ATGAAATCAAAATGTAGATTGATTGCAATTTGGTTAATGATTTCATTTAATTCGTTTATC
GAAACTGGATATGTCAAAGAAAATGGCAAACGTTTGAATGAATACATATCGCATTTTGAG
ACATTAAGTTACGATACAAAACATTTGCATGCAAAGCATAATCGTGCAAAGCGTTCCATC
GGCGAAGATCAGCATGTTCATTTAAAATTCTCAGCTCATGGTGAAACTTTTCATCTTAGA
CTTAAACGCGATTTGACTACATTTAGTGATAATTTAGAGATTCATCATACAGATAATGGC
GTAGAGAGTAAAAGGCTTTTAGATACAAGTCACATATATGAGGGTCATGTGCTTGGTGAT
AAAGACAGTTATGTTCATGGCTCGATAAGTGATGGAGTTTTCCATGGACGAATTATTACA
AATAAAGACTCATATTTTGTGGAAAAAGCTCAATATTATTTTCCTAATCATAGTCATGTA
GAAAGCGGATTTCATTCCATAATTTACAAAGACCAACATGTCGATGATCCTTATCGATTT
AATCGCACAGTTCATCCAAATGGCTGTGGACTAACCGATGATGTTGCACATTGGATGGAT
CGAGTACAAAGTTCTGCCGATGTGCTTGATGAAGAAATTGAAATTGTTCAATTGCAACAG
CAGCAACAGCAGAAAGAAAAGGAAAAGAAAGATGATAGCAAAAGTCACTCTTATCAGCAT
GTAAATAATCAAATTTATGATGAGAGTGCATATGAAAAATACTCCAAAGAAGCCAATTCA
CGGCCAAAGCGTGCAACTGTTCGTTACCAAGAGAAAAATACTTGCTCGCTTTATATTCAA
ACTGATCCACTCATTTGGCGCCATATTCGTGAATCCATTCCAGAT
>g5057.t2 Gene=g5057 Length=295
MKSKCRLIAIWLMISFNSFIETGYVKENGKRLNEYISHFETLSYDTKHLHAKHNRAKRSI
GEDQHVHLKFSAHGETFHLRLKRDLTTFSDNLEIHHTDNGVESKRLLDTSHIYEGHVLGD
KDSYVHGSISDGVFHGRIITNKDSYFVEKAQYYFPNHSHVESGFHSIIYKDQHVDDPYRF
NRTVHPNGCGLTDDVAHWMDRVQSSADVLDEEIEIVQLQQQQQQKEKEKKDDSKSHSYQH
VNNQIYDESAYEKYSKEANSRPKRATVRYQEKNTCSLYIQTDPLIWRHIRESIPD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g5057.t2 | Coils | Coil | Coil | 206 | 228 | - |
| 6 | g5057.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 220 | 242 | - |
| 5 | g5057.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 223 | 237 | - |
| 2 | g5057.t2 | PANTHER | PTHR45702 | ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER | 5 | 290 | 5.0E-47 |
| 3 | g5057.t2 | PANTHER | PTHR45702:SF2 | KUZBANIAN, ISOFORM A | 5 | 290 | 5.0E-47 |
| 1 | g5057.t2 | Pfam | PF01562 | Reprolysin family propeptide | 41 | 158 | 8.0E-12 |
| 10 | g5057.t2 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 11 | g5057.t2 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 12 | g5057.t2 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 14 | - |
| 13 | g5057.t2 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 18 | - |
| 9 | g5057.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 295 | - |
| 7 | g5057.t2 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 22 | - |
| 4 | g5057.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 25 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
Data is missing for g5057/g5057.t2; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5057.t2.fa.iupred3.txt does not exist
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed