Gene loci information

Transcript annotation

  • This transcript has been annotated as FK506-binding protein 59.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g5343 g5343.t1 TTS g5343.t1 9023904 9023904
chr_2 g5343 g5343.t1 isoform g5343.t1 9023982 9025791
chr_2 g5343 g5343.t1 exon g5343.t1.exon1 9023982 9024072
chr_2 g5343 g5343.t1 cds g5343.t1.CDS1 9023982 9024072
chr_2 g5343 g5343.t1 exon g5343.t1.exon2 9024133 9024206
chr_2 g5343 g5343.t1 cds g5343.t1.CDS2 9024133 9024206
chr_2 g5343 g5343.t1 exon g5343.t1.exon3 9024293 9024645
chr_2 g5343 g5343.t1 cds g5343.t1.CDS3 9024293 9024645
chr_2 g5343 g5343.t1 exon g5343.t1.exon4 9024714 9025506
chr_2 g5343 g5343.t1 cds g5343.t1.CDS4 9024714 9025506
chr_2 g5343 g5343.t1 exon g5343.t1.exon5 9025735 9025791
chr_2 g5343 g5343.t1 cds g5343.t1.CDS5 9025735 9025791
chr_2 g5343 g5343.t1 TSS g5343.t1 9025889 9025889

Sequences

>g5343.t1 Gene=g5343 Length=1368
ATGCCAGAAGTAATTGATTTATCAAATGATGGTGGAGTTTTGAAGGAGATATTAAAGGAA
GGAGAAGGCAAAGAACAACCATGCGATGGATGTGTTGTTTCTTGTCATTATACTGGAACA
TTACTCGATGGCACCAAATTCGATAGTTCTTTAGATCGTAATGAACCTTTTGAATTTAAA
TTGGGTAAAGGACAAGTCATTCGATCATGGGATATAGGAGTTGCATCTATGCATAAAGGT
GAAAAGTGTATGCTTACATGTGCACCTGAGTATGCATACGGCGTTAGTGGTTCTCCTCCA
AATATTCCACCTAATGCGACATTAAAATTTGAGCTCGAATTGCTCGGTTGGAAAGGTGAA
GATGTGTCGAAAAATGGAGACAATGGCATTGAACGATATGTTATTGTAAAGAGTGACAAA
AAGAAGACACCAAATGATGGTGCACGTGTGAAATGTAAAATTGTTGGAAGTTATGAAGGT
CGAGTTTTTGAAGAGCGTGATGTTGAGTTTAACATAGGCGAAGGTGAAGATTATAATATC
ATTCCTGGAGTTGAAACTGCGTTGGAGAAGATGCATGAACAAGAAACTTCGCGTTTAATT
ATTAAGCCAAAGTATGCATTTGGTTCGGAAGGAAACGAACAATTTAAAATACCACCTGAT
GCAACTGTCGAATATTTAGTTACACTTCATGAATTTGAAAGAGAAGTTGAAGCGTGGAAA
CTTGATGCTGAAGAAAGTTTGAAACAGGCTAAAATATTCAAAGAGAAAGGTACAAATTAT
TATAAATCAGATCGTTTTCAACAAGCTCTTAAATTCTATAAAAAGGGTCTTTCATTTCTA
TCAAATTGCGATACATCTGTTGAAGGTGAAGCAAGAACTGTGTCAGTCTCAATTTACTTG
AATAAAGCATTGTGCTATCAAAAACTTAATGATTACGATGAAATGAGACGTGTCTGCAAT
GAAGCATTATCAATGGAACCCAAAAATATTAAGGCTCTATATCGACGCGGTCAAGCGTAC
TTTACTCTTGGAGAAATTGAAAATGCACTTGCTGATTTTGAAGCAGTTCATGAAATTGAG
CCTGAAAACAAAGCTGCTATTAATCAAATAACTATTTGCAAGCAAAAGATCAAATCGTAT
GTGGAAGAAGAAAAGAAACGATATAAAAGTATGCTCTCCAGATATTGTTCTTCTGATGGG
TCGAAAGAAGATGTTCCACAATTAGAAGACCCTTTTGCTAATGTTTCGAAATTTGGAGAA
TGGACGGAGGAAGAAAGATCTCACACTATCACAAAATTTGAGGAAGAAAATCCGGATGTA
ATTTTGTGTGATAATGTTTTCTTTAAGGAGGAATTGAAAAATATGTAA

>g5343.t1 Gene=g5343 Length=455
MPEVIDLSNDGGVLKEILKEGEGKEQPCDGCVVSCHYTGTLLDGTKFDSSLDRNEPFEFK
LGKGQVIRSWDIGVASMHKGEKCMLTCAPEYAYGVSGSPPNIPPNATLKFELELLGWKGE
DVSKNGDNGIERYVIVKSDKKKTPNDGARVKCKIVGSYEGRVFEERDVEFNIGEGEDYNI
IPGVETALEKMHEQETSRLIIKPKYAFGSEGNEQFKIPPDATVEYLVTLHEFEREVEAWK
LDAEESLKQAKIFKEKGTNYYKSDRFQQALKFYKKGLSFLSNCDTSVEGEARTVSVSIYL
NKALCYQKLNDYDEMRRVCNEALSMEPKNIKALYRRGQAYFTLGEIENALADFEAVHEIE
PENKAAINQITICKQKIKSYVEEEKKRYKSMLSRYCSSDGSKEDVPQLEDPFANVSKFGE
WTEEERSHTITKFEEENPDVILCDNVFFKEELKNM

Protein features from InterProScan

Transcript Database ID Name Start End E.value
16 g5343.t1 Coils Coil Coil 229 249 -
15 g5343.t1 Gene3D G3DSA:3.10.50.40 - 1 121 4.5E-46
14 g5343.t1 Gene3D G3DSA:3.10.50.40 - 122 240 2.2E-31
13 g5343.t1 Gene3D G3DSA:1.25.40.10 - 242 403 6.1E-45
5 g5343.t1 PANTHER PTHR10516:SF431 PEPTIDYLPROLYL ISOMERASE 6 409 1.4E-123
6 g5343.t1 PANTHER PTHR10516 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 6 409 1.4E-123
2 g5343.t1 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 24 115 5.6E-29
3 g5343.t1 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 141 229 2.4E-16
4 g5343.t1 Pfam PF13181 Tetratricopeptide repeat 297 329 1.6E-5
1 g5343.t1 Pfam PF00515 Tetratricopeptide repeat 331 363 9.6E-8
21 g5343.t1 ProSiteProfiles PS50059 FKBP-type peptidyl-prolyl cis-trans isomerase domain profile. 30 118 29.487
20 g5343.t1 ProSiteProfiles PS50059 FKBP-type peptidyl-prolyl cis-trans isomerase domain profile. 147 233 18.166
18 g5343.t1 ProSiteProfiles PS50005 TPR repeat profile. 250 283 8.319
22 g5343.t1 ProSiteProfiles PS50293 TPR repeat region circular profile. 250 363 21.387
19 g5343.t1 ProSiteProfiles PS50005 TPR repeat profile. 296 329 9.027
17 g5343.t1 ProSiteProfiles PS50005 TPR repeat profile. 330 363 11.594
11 g5343.t1 SMART SM00028 tpr_5 250 283 0.028
12 g5343.t1 SMART SM00028 tpr_5 296 329 4.9E-5
10 g5343.t1 SMART SM00028 tpr_5 330 363 2.1E-6
9 g5343.t1 SUPERFAMILY SSF54534 FKBP-like 9 119 5.11E-41
8 g5343.t1 SUPERFAMILY SSF54534 FKBP-like 122 233 1.96E-24
7 g5343.t1 SUPERFAMILY SSF48452 TPR-like 242 392 2.1E-31

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

Data is missing for g5343/g5343.t1; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5343.t1.fa.iupred3.txt does not exist

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003755 peptidyl-prolyl cis-trans isomerase activity MF
GO:0005515 protein binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values