Gene loci information

Transcript annotation

  • This transcript has been annotated as FK506-binding protein 59.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g5343 g5343.t7 TTS g5343.t7 9023904 9023904
chr_2 g5343 g5343.t7 isoform g5343.t7 9023982 9025791
chr_2 g5343 g5343.t7 exon g5343.t7.exon1 9023982 9024072
chr_2 g5343 g5343.t7 cds g5343.t7.CDS1 9023982 9024072
chr_2 g5343 g5343.t7 exon g5343.t7.exon2 9024133 9024206
chr_2 g5343 g5343.t7 cds g5343.t7.CDS2 9024133 9024206
chr_2 g5343 g5343.t7 exon g5343.t7.exon3 9024293 9024645
chr_2 g5343 g5343.t7 cds g5343.t7.CDS3 9024293 9024645
chr_2 g5343 g5343.t7 exon g5343.t7.exon4 9024714 9025791
chr_2 g5343 g5343.t7 cds g5343.t7.CDS4 9024714 9025335
chr_2 g5343 g5343.t7 TSS g5343.t7 9025889 9025889

Sequences

>g5343.t7 Gene=g5343 Length=1596
ATGCCAGAAGTAATTGATTTATCAAATGATGGTGGAGTTTTGAAGGAGATATTAAAGGTA
AGTTAAAATTTAAATAAACATTAAATTTCCATATTCAAAAAAAGACGTAAAACAGAAGAA
TTTCGTGATAAATTCATTTTAATCTATAATTGTGGTTAAAATTGAGGCTTATATTTATTA
AAAAGAAGTTTATTTCACATTAAATGTAAAATTTCTTAGATTGAAAACAAAAAACCAAAA
GATTTCAAAACATTGTTTAATCAATTACTTTCTTTCTCTTTTTAGGAAGGAGAAGGCAAA
GAACAACCATGCGATGGATGTGTTGTTTCTTGTCATTATACTGGAACATTACTCGATGGC
ACCAAATTCGATAGTTCTTTAGATCGTAATGAACCTTTTGAATTTAAATTGGGTAAAGGA
CAAGTCATTCGATCATGGGATATAGGAGTTGCATCTATGCATAAAGGTGAAAAGTGTATG
CTTACATGTGCACCTGAGTATGCATACGGCGTTAGTGGTTCTCCTCCAAATATTCCACCT
AATGCGACATTAAAATTTGAGCTCGAATTGCTCGGTTGGAAAGGTGAAGATGTGTCGAAA
AATGGAGACAATGGCATTGAACGATATGTTATTGTAAAGAGTGACAAAAAGAAGACACCA
AATGATGGTGCACGTGTGAAATGTAAAATTGTTGGAAGTTATGAAGGTCGAGTTTTTGAA
GAGCGTGATGTTGAGTTTAACATAGGCGAAGGTGAAGATTATAATATCATTCCTGGAGTT
GAAACTGCGTTGGAGAAGATGCATGAACAAGAAACTTCGCGTTTAATTATTAAGCCAAAG
TATGCATTTGGTTCGGAAGGAAACGAACAATTTAAAATACCACCTGATGCAACTGTCGAA
TATTTAGTTACACTTCATGAATTTGAAAGAGAAGTTGAAGCGTGGAAACTTGATGCTGAA
GAAAGTTTGAAACAGGCTAAAATATTCAAAGAGAAAGGTACAAATTATTATAAATCAGAT
CGTTTTCAACAAGCTCTTAAATTCTATAAAAAGGGTCTTTCATTTCTATCAAATTGCGAT
ACATCTGTTGAAGGTGAAGCAAGAACTGTGTCAGTCTCAATTTACTTGAATAAAGCATTG
TGCTATCAAAAACTTAATGATTACGATGAAATGAGACGTGTCTGCAATGAAGCATTATCA
ATGGAACCCAAAAATATTAAGGCTCTATATCGACGCGGTCAAGCGTACTTTACTCTTGGA
GAAATTGAAAATGCACTTGCTGATTTTGAAGCAGTTCATGAAATTGAGCCTGAAAACAAA
GCTGCTATTAATCAAATAACTATTTGCAAGCAAAAGATCAAATCGTATGTGGAAGAAGAA
AAGAAACGATATAAAAGTATGCTCTCCAGATATTGTTCTTCTGATGGGTCGAAAGAAGAT
GTTCCACAATTAGAAGACCCTTTTGCTAATGTTTCGAAATTTGGAGAATGGACGGAGGAA
GAAAGATCTCACACTATCACAAAATTTGAGGAAGAAAATCCGGATGTAATTTTGTGTGAT
AATGTTTTCTTTAAGGAGGAATTGAAAAATATGTAA

>g5343.t7 Gene=g5343 Length=379
MHKGEKCMLTCAPEYAYGVSGSPPNIPPNATLKFELELLGWKGEDVSKNGDNGIERYVIV
KSDKKKTPNDGARVKCKIVGSYEGRVFEERDVEFNIGEGEDYNIIPGVETALEKMHEQET
SRLIIKPKYAFGSEGNEQFKIPPDATVEYLVTLHEFEREVEAWKLDAEESLKQAKIFKEK
GTNYYKSDRFQQALKFYKKGLSFLSNCDTSVEGEARTVSVSIYLNKALCYQKLNDYDEMR
RVCNEALSMEPKNIKALYRRGQAYFTLGEIENALADFEAVHEIEPENKAAINQITICKQK
IKSYVEEEKKRYKSMLSRYCSSDGSKEDVPQLEDPFANVSKFGEWTEEERSHTITKFEEE
NPDVILCDNVFFKEELKNM

Protein features from InterProScan

Transcript Database ID Name Start End E.value
16 g5343.t7 Coils Coil Coil 153 173 -
15 g5343.t7 Gene3D G3DSA:3.10.50.40 - 1 46 1.6E-14
14 g5343.t7 Gene3D G3DSA:3.10.50.40 - 47 164 1.6E-31
13 g5343.t7 Gene3D G3DSA:1.25.40.10 - 166 327 4.1E-45
5 g5343.t7 PANTHER PTHR10516:SF431 PEPTIDYLPROLYL ISOMERASE 1 334 1.9E-88
6 g5343.t7 PANTHER PTHR10516 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1 334 1.9E-88
2 g5343.t7 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 1 39 1.1E-7
3 g5343.t7 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 65 153 1.7E-16
4 g5343.t7 Pfam PF13181 Tetratricopeptide repeat 221 253 1.2E-5
1 g5343.t7 Pfam PF00515 Tetratricopeptide repeat 255 287 7.6E-8
21 g5343.t7 ProSiteProfiles PS50059 FKBP-type peptidyl-prolyl cis-trans isomerase domain profile. 1 42 14.583
20 g5343.t7 ProSiteProfiles PS50059 FKBP-type peptidyl-prolyl cis-trans isomerase domain profile. 71 157 18.166
17 g5343.t7 ProSiteProfiles PS50005 TPR repeat profile. 174 207 8.319
22 g5343.t7 ProSiteProfiles PS50293 TPR repeat region circular profile. 174 287 21.387
19 g5343.t7 ProSiteProfiles PS50005 TPR repeat profile. 220 253 9.027
18 g5343.t7 ProSiteProfiles PS50005 TPR repeat profile. 254 287 11.594
10 g5343.t7 SMART SM00028 tpr_5 174 207 0.028
12 g5343.t7 SMART SM00028 tpr_5 220 253 4.9E-5
11 g5343.t7 SMART SM00028 tpr_5 254 287 2.1E-6
9 g5343.t7 SUPERFAMILY SSF54534 FKBP-like 1 43 2.16E-13
8 g5343.t7 SUPERFAMILY SSF54534 FKBP-like 46 157 1.39E-24
7 g5343.t7 SUPERFAMILY SSF48452 TPR-like 166 316 1.42E-31

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

Data is missing for g5343/g5343.t7; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5343.t7.fa.iupred3.txt does not exist

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003755 peptidyl-prolyl cis-trans isomerase activity MF
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values