Gene loci information

Transcript annotation

  • This transcript has been annotated as Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g5582 g5582.t17 TSS g5582.t17 10396252 10396252
chr_2 g5582 g5582.t17 isoform g5582.t17 10396340 10398678
chr_2 g5582 g5582.t17 exon g5582.t17.exon1 10396340 10396402
chr_2 g5582 g5582.t17 exon g5582.t17.exon2 10396647 10396721
chr_2 g5582 g5582.t17 exon g5582.t17.exon3 10396780 10396843
chr_2 g5582 g5582.t17 exon g5582.t17.exon4 10396910 10397779
chr_2 g5582 g5582.t17 cds g5582.t17.CDS1 10397212 10397779
chr_2 g5582 g5582.t17 exon g5582.t17.exon5 10397836 10397911
chr_2 g5582 g5582.t17 cds g5582.t17.CDS2 10397836 10397911
chr_2 g5582 g5582.t17 exon g5582.t17.exon6 10398603 10398678
chr_2 g5582 g5582.t17 cds g5582.t17.CDS3 10398603 10398603
chr_2 g5582 g5582.t17 TTS g5582.t17 10398686 10398686

Sequences

>g5582.t17 Gene=g5582 Length=1224
ATGGCGCTTGCTGTTCGATTTGCAAAGCAATCAACTGAGAAGTTGTCACCGCTCTTGAGA
AGAAACTTCTGCTCTGCATACGAATTGCAACACAAAAATCCTATTCAAAAACGAATTGCT
GCAATCCCAAAAGCTCAATATGGAGGTAGACACACGGTCACAATGCTCCCTGGTGGTGGA
ATCGGATTAGAGCTCTCAAACTAAATTTTCCGCTATGCAGGTGTTCCTGTTGATTTTGAA
GTTATTGATATAGATCCAAATAGCGAAACCAATGATGATTTAGATTATGCAATTACATCA
ATTAAACGTAATGGTGTTGCAATTAAGGGAAATATTGAGACAAAAAGTGAAGCAACTGGA
ATTATCTCAAGAAATGTTGCATTGCGAAATGAATTAGATTTGTTTGTCAATGTATTGCAT
TGCAAATCATATCCTGGTGTGAGATCTCACCATAAAGACATTGATTTAATTGTTGTACGT
CAAAATACAGAAGGTGAGTATGCGATGTTGGAACACGAGTCAGTGCGAGGTGTTGTTGAG
TCATTGAAAATTATAACTGTGGAAGCTAGTGAGAGATTAAGTCGATTTGCATTCGAATAT
GCTCGCAAAAATGGTCGCAAGAAGGTGACAACTATTCATAAAGCTAACATCATGAAGCTC
TCCGATGGATGCTTCCTAGAAACTTCAAAGCGTATTGCCAAAGAATATCCAGATATCGAG
CACAATAATATGATTATTGACAATACATGCATGCAATTGGTGGCAAAGCCTCAACAATTT
GATGTTCTTTTAACAACTAATTTGTATGGATCAATTTGCACAAATGTAATTTGTGGATTA
GTTGGAGGAGCTGGTTTATATAGCGGACGTAACTATGGTGATCATTATGCTGTCTTTGAG
CCAGGCACACGTAACACAGGAAGCTCAATTGCTGGAAAGAATATTTGCAATCCTTTTGCA
ATGCTTAATGCAAGTGTTGACATGTTGAATCATCTTGGTCATACTCAACATGCAAATGCC
ATCTCTACAGCCATATACGAGACAATTGTCAAAGATAAAATTCATACAGCCGACCTTGGT
GGAACTGCATCTTCAACCGATTGTATTCAAAATGTGTTGAAGCATCTTGCAGCTGGACAA
GTTTCTTGATTTAAAATACTGAAAAACTAATAATTTATTATTTATTGTTAAAAACATGAA
ATAAAGAAGAAAGAAAAAAGACAC

>g5582.t17 Gene=g5582 Length=214
MLEHESVRGVVESLKIITVEASERLSRFAFEYARKNGRKKVTTIHKANIMKLSDGCFLET
SKRIAKEYPDIEHNNMIIDNTCMQLVAKPQQFDVLLTTNLYGSICTNVICGLVGGAGLYS
GRNYGDHYAVFEPGTRNTGSSIAGKNICNPFAMLNASVDMLNHLGHTQHANAISTAIYET
IVKDKIHTADLGGTASSTDCIQNVLKHLAAGQVS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g5582.t17 Gene3D G3DSA:3.40.718.10 Isopropylmalate Dehydrogenase 1 213 0
2 g5582.t17 PANTHER PTHR11835 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE 1 209 0
3 g5582.t17 PANTHER PTHR11835:SF60 ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL 1 209 0
1 g5582.t17 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 10 196 0
5 g5582.t17 SMART SM01329 Iso_dh_2 2 204 0
4 g5582.t17 SUPERFAMILY SSF53659 Isocitrate/Isopropylmalate dehydrogenase-like 5 208 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

Data is missing for g5582/g5582.t17; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5582.t17.fa.iupred3.txt does not exist

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor MF
GO:0055114 NA NA

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed