Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Cation-independent mannose-6-phosphate receptor.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g567 g567.t6 TSS g567.t6 4167939 4167939
chr_3 g567 g567.t6 isoform g567.t6 4168099 4171502
chr_3 g567 g567.t6 exon g567.t6.exon1 4168099 4168164
chr_3 g567 g567.t6 exon g567.t6.exon2 4168457 4168676
chr_3 g567 g567.t6 exon g567.t6.exon3 4168784 4168850
chr_3 g567 g567.t6 exon g567.t6.exon4 4168915 4170520
chr_3 g567 g567.t6 cds g567.t6.CDS1 4169023 4170520
chr_3 g567 g567.t6 exon g567.t6.exon5 4170581 4170648
chr_3 g567 g567.t6 cds g567.t6.CDS2 4170581 4170648
chr_3 g567 g567.t6 exon g567.t6.exon6 4170710 4171009
chr_3 g567 g567.t6 cds g567.t6.CDS3 4170710 4171009
chr_3 g567 g567.t6 exon g567.t6.exon7 4171422 4171502
chr_3 g567 g567.t6 cds g567.t6.CDS4 4171422 4171502
chr_3 g567 g567.t6 TTS g567.t6 4171812 4171812

Sequences

>g567.t6 Gene=g567 Length=2408
ATGAAGTATTTCGCAATTTTCCTGCTTGTGATAAATTTCTGCAATATAATTGCAATAGAT
CAAACAAAAGACGTTGAAGGAGCAAATTGTTCAGTGACAGAGACAATTGGAAATTATACA
TTTAATTTTACTGAACTTAGTAGTGACTTTGGATATCACATCGATGGAAATGCAGAAGAT
ATGGGAAAATATAGTTTCAATCTTTGTAAACCGCTATCAAGAAAATGCAACAACCAAACA
GCTGCAGCTTGTCTGAAAAATGTTGACGGCAAGGAAATCATAATAGGATACGACAGCACT
TCAAAATTATTTTGGAATGACGGTCAAATAAGATTCAGTTTCATTGGCGAAAAAATGATT
TTCTTGGCGTGTTTCATGATGATAGCGAATGTGAAGTTACAATACTTATGCGAACGCCAA
AGGCGTGTTTAGAAATTCCTGAAAATGTCAAAAATGCAAAGATGTACGTAACTAGTCCCA
ATGGCAAGATTTTGAATTTCAACGCTTTAAAAAGTTCAAACCATATTATCAATGGTCCAA
ATGATGGAACTTTCATAATTGGTTTTCCAATTACTTACGAACATGGAATTTTATGTGAAG
CTGGCTCATCTATTTGTTATGTCGACAAGAATGAGACTGATTTATCAAAGAAATATACCA
ATATGGGAACGATGACATCTAATATTGAATTTGAAAATGATCGACCAGTCATTAAATTTA
CAAGCAAAGAAAAATGCAATAATAACACATTGGGCTCATCAAAAATTGTTTTCGAATGTG
ATCGATTCAAAAAAGAAGGTACACCTAAATTTAAAGGTGTAAAAGATTGTGTAAGCAATT
TTGTTTGGGAAACATCACTTGCATGTTACGATGAAAAACCTTGTGTTGTATCTGGAGAAA
ATGGTGATCAATACGATTTTAGTTCACTCGCAAATGTTCAATATGAAGTTAAAATTCCAA
ACAAGACTGATGAAACCATTTACTTTTCTATTTGCTCAAATTCAAAAGAATGTGGTGAAG
GCAACTGGGGTAGTTGCATTGTAAAAAATACAGGTGGCAATAAACAAACAACAAAAGTAG
GCATCTTCAATGCAAAACTTCAAGTCGAGAAGAAAAATGTATTTTTGAAATATGATGAAG
GTTCTCAATGTGGTGATCCGAAAGATAAGAAAAAATATTCAACAAGAATCGAATTTAATG
TTGCTGATAGCCCAAATGATGAAGAAATTGTATTAATTGAGGATAAATGTGAAATTGTCA
TTCACTTCAAGACACTCTTGGCTAATCAACATGTAAAGAATTGCGTCGTTAAAAATTTAG
ATGATGAAGAAATAGACTTGAGGCCATTAATCGACTATAATGGAAATTATTTGGCAAGAG
TAAATGAAACAACCTTGCCAAATGAAACGTCAAAAAATAATGTGTCCTACTTGTTGAATG
TATGTCGCCCGATAAATTCATTTTATTCATTAAATTGTCATGGAAATACTGGCGCTTGTA
GAACAATCATGAAAGATGAAAAACACGAAGAGGAAATAAGCTTAGGTCACTTTGAATATT
TTATGTCTACTGAAAAGGGAAAAATTGAAGGTACAAACAATGTTATAATGAAATATTTCC
ATGGATCAAAATGTCCAACTGATAAAGAGGAAGAGATAACAACGAAAGTTAAATTCTATT
GTGATGAGAATGCTGGTTTGGGAAGTCCTATTTTACAATCTATTGAGCATTGTGAATATT
CATTTGAATTTCCAACCAGCATCTTATGCAATGATAAGCGTGTCAATCTGAAAAGCAATG
AATCGTGCATACTGACGAATGGTGATTCGAGTGTCAATTTGAAATCTTATGGAAATTTCA
ATACAAGCAACAGAAACATAAGTTTGTGTGATGCACTTGTGAAGACATACACTATCAGCT
ATAAACAATCAATGGTTATTATTGAATATGTTGATAAAGATTACGTCGATATAGAAGTTC
AACTTAAATGTAATTTGAAAAATAATACATTTGTTGATGTTAGCAATGAGGGTATCATCA
TTATGAATGAGTCACCTTTGATTTGTCCACTTTTGCATATCGTACCAAAAGCTACACCAT
CACAGAATGAAGTTGATAACGATAACAATGATGTGCTAGAGATGTCATTAAACAATGATA
TAATAATACCAAAATCAAGCAAATTTCCATTGGGTTATTTGTTCCTAATTTCAATTTTGA
TTGCTGCATTTGGAATTTTCTATATTGTCATAAGAAATCCTGAGCGTCGCGACATAATTC
GCAATATGATTAAATTCCGATCTCGGTCAAATGTTCGATACACACGAGTGCGACTTAATG
AAGAATCAGCCCTCTTAGATGGTAATAGTCCAAATTCAGATAGTGATGATGAGAATATTT
TGCTGTAA

>g567.t6 Gene=g567 Length=648
MYVTSPNGKILNFNALKSSNHIINGPNDGTFIIGFPITYEHGILCEAGSSICYVDKNETD
LSKKYTNMGTMTSNIEFENDRPVIKFTSKEKCNNNTLGSSKIVFECDRFKKEGTPKFKGV
KDCVSNFVWETSLACYDEKPCVVSGENGDQYDFSSLANVQYEVKIPNKTDETIYFSICSN
SKECGEGNWGSCIVKNTGGNKQTTKVGIFNAKLQVEKKNVFLKYDEGSQCGDPKDKKKYS
TRIEFNVADSPNDEEIVLIEDKCEIVIHFKTLLANQHVKNCVVKNLDDEEIDLRPLIDYN
GNYLARVNETTLPNETSKNNVSYLLNVCRPINSFYSLNCHGNTGACRTIMKDEKHEEEIS
LGHFEYFMSTEKGKIEGTNNVIMKYFHGSKCPTDKEEEITTKVKFYCDENAGLGSPILQS
IEHCEYSFEFPTSILCNDKRVNLKSNESCILTNGDSSVNLKSYGNFNTSNRNISLCDALV
KTYTISYKQSMVIIEYVDKDYVDIEVQLKCNLKNNTFVDVSNEGIIIMNESPLICPLLHI
VPKATPSQNEVDNDNNDVLEMSLNNDIIIPKSSKFPLGYLFLISILIAAFGIFYIVIRNP
ERRDIIRNMIKFRSRSNVRYTRVRLNEESALLDGNSPNSDSDDENILL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g567.t6 Gene3D G3DSA:2.70.130.10 - 2 138 2.3E-18
15 g567.t6 Gene3D G3DSA:2.70.130.10 - 139 279 5.4E-20
14 g567.t6 Gene3D G3DSA:2.70.130.10 - 280 440 8.0E-29
3 g567.t6 PANTHER PTHR15071 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER 54 246 1.9E-43
5 g567.t6 PANTHER PTHR15071:SF17 CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR 54 246 1.9E-43
4 g567.t6 PANTHER PTHR15071 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER 166 454 1.9E-43
6 g567.t6 PANTHER PTHR15071:SF17 CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR 166 454 1.9E-43
2 g567.t6 Pfam PF00878 Cation-independent mannose-6-phosphate receptor repeat 100 231 1.8E-17
1 g567.t6 Pfam PF00878 Cation-independent mannose-6-phosphate receptor repeat 238 391 4.3E-10
17 g567.t6 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 576 -
18 g567.t6 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 577 597 -
16 g567.t6 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 598 648 -
12 g567.t6 SMART SM01404 CIMR_2 95 231 8.3E-24
11 g567.t6 SMART SM01404 CIMR_2 236 392 1.1E-14
9 g567.t6 SUPERFAMILY SSF50911 Mannose 6-phosphate receptor domain 2 135 2.09E-16
8 g567.t6 SUPERFAMILY SSF50911 Mannose 6-phosphate receptor domain 140 273 9.94E-15
10 g567.t6 SUPERFAMILY SSF50911 Mannose 6-phosphate receptor domain 262 436 3.92E-23
7 g567.t6 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 575 597 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

Data is missing for g567/g567.t6; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g567.t6.fa.iupred3.txt does not exist

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0038023 signaling receptor activity MF
GO:0007041 lysosomal transport BP
GO:0005537 mannose binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values