General information for g5718.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Adenylate kinase isoenzyme 1.
Parent gene
- The parent gene g5718 is located on chr_2: 11379536..11382717 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g5718 | g5718.t1 | TTS | g5718.t1 | 11379234 | 11379234 |
| chr_2 | g5718 | g5718.t1 | isoform | g5718.t1 | 11379536 | 11380812 |
| chr_2 | g5718 | g5718.t1 | exon | g5718.t1.exon1 | 11379536 | 11379848 |
| chr_2 | g5718 | g5718.t1 | cds | g5718.t1.CDS1 | 11379536 | 11379848 |
| chr_2 | g5718 | g5718.t1 | exon | g5718.t1.exon2 | 11379911 | 11380130 |
| chr_2 | g5718 | g5718.t1 | cds | g5718.t1.CDS2 | 11379911 | 11380130 |
| chr_2 | g5718 | g5718.t1 | exon | g5718.t1.exon3 | 11380198 | 11380249 |
| chr_2 | g5718 | g5718.t1 | cds | g5718.t1.CDS3 | 11380198 | 11380249 |
| chr_2 | g5718 | g5718.t1 | exon | g5718.t1.exon4 | 11380756 | 11380812 |
| chr_2 | g5718 | g5718.t1 | cds | g5718.t1.CDS4 | 11380756 | 11380812 |
| chr_2 | g5718 | g5718.t1 | TSS | g5718.t1 | 11381744 | 11381744 |
Sequences
>g5718.t1 Gene=g5718 Length=642
ATGGCAAATGAACATGAGAAAAAACAAAAGGAAAAATCATCATCACGACAAACGTCTGTT
GTTGATTCAAAGACTCCAATTATTTGGGTTTTAGGCGGACCAGGATGCGGCAAGGGAACA
CAGTGTGATAAGATTGTTGCCAAGTATGGCTTTAACCACCTTTCAACTGGCGACTTACTA
CGTGCTGAAGTAGCTTCAGGTTCAGTAAAGGGTCAAGAGTTGTTGAGTATCATGAAAACA
GGTGGATTAGTTAGCAATGAAGCAGTTCTTGAACTTCTTGCTGCTGCTATGTCAAAAATT
GAAAATGCCAAAGGATTTCTTATTGATGGATACCCAAGAGAGGAAGCACAAGGACGAGAA
TTTGAAAAGCTTATTCGTCCAGTTGATCTCGTTCTTTACTTTGAATGCTCCAATGAAACA
CTTGTGAATCGTATTCTTGTTCGTGCTGCTGCCTCTGTTGAAAAGCGTGCTGATGATAAT
GAAGAAACTTTAAAGACAAGAATCGCAACATTCAGAGCCAATACTGAGAAAATTCTAATT
CAATATCCTGATAAACTTAGACGCATTAATGCCGAACGTGGAGTTGATGAAATTTTTGCA
GAAGTATCTGATGCCATTGATGCTACATTAGCTAAAAAATAA
>g5718.t1 Gene=g5718 Length=213
MANEHEKKQKEKSSSRQTSVVDSKTPIIWVLGGPGCGKGTQCDKIVAKYGFNHLSTGDLL
RAEVASGSVKGQELLSIMKTGGLVSNEAVLELLAAAMSKIENAKGFLIDGYPREEAQGRE
FEKLIRPVDLVLYFECSNETLVNRILVRAAASVEKRADDNEETLKTRIATFRANTEKILI
QYPDKLRRINAERGVDEIFAEVSDAIDATLAKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g5718.t1 | CDD | cd01428 | ADK | 27 | 198 | 4.42877E-64 |
| 10 | g5718.t1 | Gene3D | G3DSA:3.40.50.300 | - | 12 | 209 | 3.1E-58 |
| 4 | g5718.t1 | Hamap | MF_00235 | Adenylate kinase [adk]. | 26 | 207 | 34.717617 |
| 13 | g5718.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 20 | - |
| 14 | g5718.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 17 | - |
| 2 | g5718.t1 | PANTHER | PTHR23359 | NUCLEOTIDE KINASE | 8 | 207 | 3.6E-67 |
| 3 | g5718.t1 | PANTHER | PTHR23359:SF70 | ADENYLATE KINASE 1, ISOFORM B | 8 | 207 | 3.6E-67 |
| 7 | g5718.t1 | PRINTS | PR00094 | Adenylate kinase signature | 29 | 42 | 1.0E-24 |
| 5 | g5718.t1 | PRINTS | PR00094 | Adenylate kinase signature | 57 | 71 | 1.0E-24 |
| 8 | g5718.t1 | PRINTS | PR00094 | Adenylate kinase signature | 106 | 122 | 1.0E-24 |
| 6 | g5718.t1 | PRINTS | PR00094 | Adenylate kinase signature | 156 | 171 | 1.0E-24 |
| 1 | g5718.t1 | Pfam | PF00406 | Adenylate kinase | 30 | 183 | 8.0E-45 |
| 12 | g5718.t1 | ProSitePatterns | PS00113 | Adenylate kinase signature. | 106 | 117 | - |
| 9 | g5718.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 26 | 206 | 9.63E-34 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
Data is missing for g5718/g5718.t1; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5718.t1.fa.iupred3.txt does not exist
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
| GO:0019205 | nucleobase-containing compound kinase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00939 (adenylate kinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
