Gene loci information

Transcript annotation

  • This transcript has been annotated as 4-hydroxyphenylpyruvate dioxygenase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g5758 g5758.t22 isoform g5758.t22 11776293 11777800
chr_2 g5758 g5758.t22 exon g5758.t22.exon1 11776293 11776932
chr_2 g5758 g5758.t22 cds g5758.t22.CDS1 11776438 11776932
chr_2 g5758 g5758.t22 exon g5758.t22.exon2 11777355 11777800
chr_2 g5758 g5758.t22 cds g5758.t22.CDS2 11777355 11777429
chr_2 g5758 g5758.t22 TTS g5758.t22 11777800 11777800
chr_2 g5758 g5758.t22 TSS g5758.t22 NA NA

Sequences

>g5758.t22 Gene=g5758 Length=1086
TTTGATTGATCGCAAAAATTACAAAGGAATTTTCTTGCCTGGTTATAAAGAACATTATTC
CAAGAATGATCCACTTCTTAAAATTTTGCCAAAGCCAAATTTACAATTTATTGATCATAT
CGTTGGCAATCAACCAGATCGACAAATGGAATCAGTTGCTGAATGGTATGTTCGCTGTTT
AATGTTTCATCGCTTTTGGTCGGTTGATGACAGTCAAATTCACACTGAATTTTCTGCCTT
ACGTTCAATTGTTGTTACTAATTATGAAGAGACAATCAAAATGCCCATTAATGAGCCAGC
ATCAGGAAAGAAAAAATCACAAATTCAAGAATATGTGGACTATTATGCCAGTGGTGGTGT
TCAACATATTGCATTGAATACAAACGATATTATCGATACAATTACAAAACTTAAGGAACG
TGGACAAGATTTCTTAGTTGTTCCAGATACTTATTATGATATGCTTGAAAAACGATTGGC
AGCTGACAATTTCAAAATCAAAGAAGATTTGGCAGTGTTGAAAAAATTGAAAATTTTAAT
TGATTATGATCAAACTGGATATTTGCTTCAAATTTTTACTAAAAACATGCAAGATCGTCC
AACACTTTTCTTGGAAGTTATTCAACGTCGCAATCATAATGGTTTCGGAGCAGGAAATTT
CAAAGCCCTTTTTGAAGCAATCGAATTGGATCAAGCACAACGTGGCAATTTGTAATCTTT
TTCCTTCAATATTCTCAAACGGAATCAATAATAACGACTCTGTTCTAGCTTTTCTGTTCT
TTTATTGTTTCTTTAGTTTTTTGAGAACAGAAAAAAAACTTCTTTTCTTCTTTTATTCAT
AAAATCACATTTCGACAGCAGTGAAATTTCTTTTCTTTTCATTTGATTAAAAATAACAAA
AGAGAAAAAAGTCTAAGTACAGTAGTGGAAAAGGAGGATATCCTAATAAACTGCAGGAGC
GATGATAACAATATTGAATATTAAATGCAAATTTTTCTCTCTTCATACAATTTCTTAATG
AAAAAAGAGAATATTCTGCAATATATACAAAAAGAAATAAAGGATATTGCTGCTGGATGC
AAAAAT

>g5758.t22 Gene=g5758 Length=189
MESVAEWYVRCLMFHRFWSVDDSQIHTEFSALRSIVVTNYEETIKMPINEPASGKKKSQI
QEYVDYYASGGVQHIALNTNDIIDTITKLKERGQDFLVVPDTYYDMLEKRLAADNFKIKE
DLAVLKKLKILIDYDQTGYLLQIFTKNMQDRPTLFLEVIQRRNHNGFGAGNFKALFEAIE
LDQAQRGNL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g5758.t22 CDD cd07250 HPPD_C_like 1 180 0.000
5 g5758.t22 Gene3D G3DSA:3.10.180.10 2 1 189 0.000
2 g5758.t22 PANTHER PTHR11959 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 1 189 0.000
3 g5758.t22 PANTHER PTHR11959:SF12 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 1 189 0.000
1 g5758.t22 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 1 132 0.000
7 g5758.t22 ProSiteProfiles PS51819 Vicinal oxygen chelate (VOC) domain profile. 1 146 19.017
4 g5758.t22 SUPERFAMILY SSF54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 1 176 0.000
6 g5758.t22 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 1 189 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

Data is missing for g5758/g5758.t22; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5758.t22.fa.iupred3.txt does not exist

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0009072 aromatic amino acid family metabolic process BP
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen MF
GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity MF
GO:0055114 NA NA

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed