General information for g5976.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dopamine N-acetyltransferase.
Parent gene
- The parent gene g5976 is located on chr_2: 13120887..13122534 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g5976 | g5976.t1 | TTS | g5976.t1 | 13120631 | 13120631 |
| chr_2 | g5976 | g5976.t1 | isoform | g5976.t1 | 13120887 | 13122534 |
| chr_2 | g5976 | g5976.t1 | exon | g5976.t1.exon1 | 13120887 | 13121297 |
| chr_2 | g5976 | g5976.t1 | cds | g5976.t1.CDS1 | 13120887 | 13121297 |
| chr_2 | g5976 | g5976.t1 | exon | g5976.t1.exon2 | 13121358 | 13121510 |
| chr_2 | g5976 | g5976.t1 | cds | g5976.t1.CDS2 | 13121358 | 13121510 |
| chr_2 | g5976 | g5976.t1 | exon | g5976.t1.exon3 | 13122211 | 13122363 |
| chr_2 | g5976 | g5976.t1 | cds | g5976.t1.CDS3 | 13122211 | 13122363 |
| chr_2 | g5976 | g5976.t1 | exon | g5976.t1.exon4 | 13122460 | 13122534 |
| chr_2 | g5976 | g5976.t1 | cds | g5976.t1.CDS4 | 13122460 | 13122534 |
| chr_2 | g5976 | g5976.t1 | TSS | g5976.t1 | NA | NA |
Sequences
>g5976.t1 Gene=g5976 Length=792
ATGGCTGTTCAGTATCAAAATCAAGTCACTCTCGAGACATCATTCATTCGTCAAGATGCC
GGCAAAATTATGGTCGAATTGTCGGAAATTCTTCCACCAATTCATCAATTGGTGAATCAA
ATGGCGGCTGTAACGATTGATTCCAAAGAACAAAAACTCTCTTATGAAACAATCACAAAT
GATGATGAAGAAGAAGTTATCGAATTGCTAAAGAAAACATTCTTTAAGGACGAGCCATTG
AATGAATATCTACAACTGGGTGAATGTAAGGACTTGGAAGATTATTGCAAAAAGAGCATT
CCAGATGGATGCTCTTTCAAAGCTGTCAATTCAAATGGAGAAATTGTGGGTGTTTTCCTA
AATGGAATTATTCGAAAGCCAGAACCCAATGACGAGCCAGTTTTGTTGGCATCAAAAACT
AATCATGAAAAGTTCAAAATCATCATGCAGTTAATGGACTACATCGACTCAAAATTCAGT
ATTTTTGATTTATATCCAGACATTGAAGCATTTATTGACGGAAAAATTTTAGCTGTGGAT
CCACGATATCGTGGTTATGGAATTGCAGGACAATTAACAGACAAGACAATTGAATTTATG
CAGCAAAATAATTACAAAGTGTTCCATGTTCTCTGTTCATCTCATTTCTCAGCAAGAGTG
CTCGAAAAAATGGACTTTACAGAAGTTTTTCGATTAAACTATGAGGAATATATAGTTGAT
GGCAAAAAAGTTTTATGCCCAGAGAAACCACATGTCGCTGCACGAATTTTTACAAAAGTC
ATTTCCTCTTAA
>g5976.t1 Gene=g5976 Length=263
MAVQYQNQVTLETSFIRQDAGKIMVELSEILPPIHQLVNQMAAVTIDSKEQKLSYETITN
DDEEEVIELLKKTFFKDEPLNEYLQLGECKDLEDYCKKSIPDGCSFKAVNSNGEIVGVFL
NGIIRKPEPNDEPVLLASKTNHEKFKIIMQLMDYIDSKFSIFDLYPDIEAFIDGKILAVD
PRYRGYGIAGQLTDKTIEFMQQNNYKVFHVLCSSHFSARVLEKMDFTEVFRLNYEEYIVD
GKKVLCPEKPHVAARIFTKVISS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g5976.t1 | CDD | cd04301 | NAT_SF | 169 | 210 | 0.000540 |
| 5 | g5976.t1 | Gene3D | G3DSA:3.40.630.30 | - | 48 | 260 | 0.000000 |
| 2 | g5976.t1 | PANTHER | PTHR20905:SF31 | DOPAMINE N-ACETYLTRANSFERASE | 45 | 261 | 0.000000 |
| 3 | g5976.t1 | PANTHER | PTHR20905 | N-ACETYLTRANSFERASE-RELATED | 45 | 261 | 0.000000 |
| 1 | g5976.t1 | Pfam | PF00583 | Acetyltransferase (GNAT) family | 66 | 226 | 0.000062 |
| 6 | g5976.t1 | ProSiteProfiles | PS51186 | Gcn5-related N-acetyltransferase (GNAT) domain profile. | 53 | 245 | 9.614000 |
| 4 | g5976.t1 | SUPERFAMILY | SSF55729 | Acyl-CoA N-acyltransferases (Nat) | 54 | 235 | 0.000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
Data is missing for g5976/g5976.t1; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5976.t1.fa.iupred3.txt does not exist
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008080 | N-acetyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00669 (arylalkylamine N-acetyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
