Gene loci information

Transcript annotation

  • This transcript has been annotated as ATP-binding cassette sub-family G member 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6039 g6039.t1 isoform g6039.t1 13749137 13759878
chr_2 g6039 g6039.t1 exon g6039.t1.exon1 13749137 13749264
chr_2 g6039 g6039.t1 cds g6039.t1.CDS1 13749137 13749264
chr_2 g6039 g6039.t1 exon g6039.t1.exon2 13753074 13753191
chr_2 g6039 g6039.t1 cds g6039.t1.CDS2 13753074 13753191
chr_2 g6039 g6039.t1 exon g6039.t1.exon3 13756734 13756880
chr_2 g6039 g6039.t1 cds g6039.t1.CDS3 13756734 13756880
chr_2 g6039 g6039.t1 exon g6039.t1.exon4 13756986 13757044
chr_2 g6039 g6039.t1 cds g6039.t1.CDS4 13756986 13757044
chr_2 g6039 g6039.t1 exon g6039.t1.exon5 13757291 13757615
chr_2 g6039 g6039.t1 cds g6039.t1.CDS5 13757291 13757615
chr_2 g6039 g6039.t1 exon g6039.t1.exon6 13757894 13758845
chr_2 g6039 g6039.t1 cds g6039.t1.CDS6 13757894 13758845
chr_2 g6039 g6039.t1 exon g6039.t1.exon7 13758943 13759043
chr_2 g6039 g6039.t1 cds g6039.t1.CDS7 13758943 13759043
chr_2 g6039 g6039.t1 exon g6039.t1.exon8 13759265 13759435
chr_2 g6039 g6039.t1 cds g6039.t1.CDS8 13759265 13759435
chr_2 g6039 g6039.t1 exon g6039.t1.exon9 13759491 13759608
chr_2 g6039 g6039.t1 cds g6039.t1.CDS9 13759491 13759608
chr_2 g6039 g6039.t1 exon g6039.t1.exon10 13759667 13759878
chr_2 g6039 g6039.t1 cds g6039.t1.CDS10 13759667 13759878
chr_2 g6039 g6039.t1 TTS g6039.t1 13760194 13760194
chr_2 g6039 g6039.t1 TSS g6039.t1 NA NA

Sequences

>g6039.t1 Gene=g6039 Length=2331
ATGGCGGAAGGAAAAGTTCATTTTCAAATGGAAGGCAATCAACTGCCACCATATTACTCG
TCCAACTCAAACAGCCTCAAATCACCACCGACAACGACCAATTTTAAAAACACAGTGGCT
GCTTTAGGTGGCTCACAGAATAATTTAAATATATGCAATGGATCAATAATCATGGGTGGT
AGCAGTGATAAACATGGATTAGTGCGGAAAATTCCAAATGAAATGAGCTGCCAGAAGAAA
CCTACGGTACAATTGACACATCTCCTTCAACGACCACCCGTCGATATTGAATTTCAAAAA
ATTTCTTATTCAGTATCAGAGGGTCGAGCGCGAGGCTATAAGACAATTTTGAAAGGAATA
AATGGAAAATTTCGATCCGGAGAGCTTGCGGCTATCATGGGCCCTTCCGGTGCTGGAAAG
AGCACTTTGATGAATATTCTTGCTGGATACAAAACGTCAAACCTGAGTGGTCACGTATTG
ATAAATGGCAAAGAGCGCAATTTGCGACGTTTTAGGAAATTAAGTTGTTATATCATGCAA
GATGATCAGCTGCTGCCGTATTTAACAGTTCGTGAAGCTATGCTCGTGAGTGCAAATTTA
AAACTTGGCAAAGATCTTACTGAAGGTGCTAAGAAAATCATCATTGATGAAATTATTGAT
GCATTGGGTTTATCAGAATGTGCAGCAACAAAGACAATAAGTTTATCGGGCGGCCAACGA
AAACGTCTGTCAGTTGCACTCGAACTTGTGAATAATCCTCCCGTAATGTTCCTTGATGAA
CCAACAAGTGGTCTTGACAGTTCATCATGCTTTCAACTCATTTCACTTCTTAAATCACTT
GCACGTGGTGGTCGAACAATTGTCTGCACCATTCATCAACCCTCGGCACGTCTTTTCGAG
ATGTTTGATAATCTATATATGCTTGCTGAGGGTCAATGCATCTATCAAGGAGTCGTGAAC
GGTCTTGTTCCATTTCTAGCATCGAATGGTTATATTTGCCCAAGCTACCACAATCCGGCA
GATTATGTAATGGAAATTGCATGCGGTGAACATGGTGAAGCTGTCTACAAGCTCGTCACA
GCCATGAACAATCGTAAAAGCATCAACAACTTTGGTCAAGATGCGCTTTTGTCAGTTGAA
AAACCACTCAATCTTTCGACTATTGCCATTCCCTCTTCATCGACATCCGCATCCGCATCG
ACAACTACAACAACAATAAGCAATGATACTGCGGCGAATGGTAATGGGCCACTTGCAGCA
CATATTGTCGCACATGACAGTGTCGTGGTAGATGTTGATTTGGTTAAAAATAGTAGTGGA
CGAGCAGAATATACGATTATAAATATGAATCAATCAAAAATTGAACAAAATGGCAACAAT
TCACAACAACAGCAACAAATCGGACCAACAACTTCACTTTTAGATTCATCAACCGAAAGT
GTCATTGTGATGGGCAAAAAAGATACACATAAAAATCACATCAACGGATTTCCTACAAGT
AGTTGGACGCAATTTTGGATTCTTCTCAAACGAACATTCCTCACAATCATACGAGATCAA
ACATTGACACAAATGCGACTCGTTTCACACATCGTTGTAGGCGCAATAATTGGAATGATT
TATTATGGAATTGGTAATGATGCGAGTAAAATTATGAGCAACACCGGCTGCTTATTTTTC
ACGACATTATTCACAATGTTTACCGCAATGATGCCTACAATTTTGACATTTCCCTCTGAA
ATGTCTGTATTTATACGAGAACATCTTAATTATTGGTACTCGCTGAAGTCATATTATTTT
GCCAAAACGATAGCTGATTTGCCTTTTCAGGTTCTTTTTACAAGCGTCTATGTGCTTGTA
GTATACTTGCTAACAAATCAACCGATGGAGGCAGATCGCATTGCGATGTTTGTGTTAATT
TGCATTCTCACTTCGCTTGTAGCGCAAAGTTTGGGACTTTTAATAGGCGCTGGAATGAGT
GTTGAAACTGGAACGTTCCTTGGTCCAGTAACAACAATTCCAACGATATTATTTTCTGGC
TTCTTTGTCAATTTCAATGTCATTCCAAATTATCTTAAATGGGTCACATATGTCAGTTAT
GTAAGATTTGGATTTGAAGGTGCTATGATATCCGTTTATGGACTTGGTCGTGAGAAACTC
GAATGCGATGAAATCTACTGTCATTATCGTGACCCTAAAAAGTTTCTTGCGGAAATGTCA
ATGGCTGATGCTAATTTTTGGGTTGATGCTGCCGCTTTAGCTGGAATTTTTGTTGGACTG
AGAATTATTGCATATTTTGTACTTCGATGGAAACTTCATTCAATACGTTAA

>g6039.t1 Gene=g6039 Length=776
MAEGKVHFQMEGNQLPPYYSSNSNSLKSPPTTTNFKNTVAALGGSQNNLNICNGSIIMGG
SSDKHGLVRKIPNEMSCQKKPTVQLTHLLQRPPVDIEFQKISYSVSEGRARGYKTILKGI
NGKFRSGELAAIMGPSGAGKSTLMNILAGYKTSNLSGHVLINGKERNLRRFRKLSCYIMQ
DDQLLPYLTVREAMLVSANLKLGKDLTEGAKKIIIDEIIDALGLSECAATKTISLSGGQR
KRLSVALELVNNPPVMFLDEPTSGLDSSSCFQLISLLKSLARGGRTIVCTIHQPSARLFE
MFDNLYMLAEGQCIYQGVVNGLVPFLASNGYICPSYHNPADYVMEIACGEHGEAVYKLVT
AMNNRKSINNFGQDALLSVEKPLNLSTIAIPSSSTSASASTTTTTISNDTAANGNGPLAA
HIVAHDSVVVDVDLVKNSSGRAEYTIINMNQSKIEQNGNNSQQQQQIGPTTSLLDSSTES
VIVMGKKDTHKNHINGFPTSSWTQFWILLKRTFLTIIRDQTLTQMRLVSHIVVGAIIGMI
YYGIGNDASKIMSNTGCLFFTTLFTMFTAMMPTILTFPSEMSVFIREHLNYWYSLKSYYF
AKTIADLPFQVLFTSVYVLVVYLLTNQPMEADRIAMFVLICILTSLVAQSLGLLIGAGMS
VETGTFLGPVTTIPTILFSGFFVNFNVIPNYLKWVTYVSYVRFGFEGAMISVYGLGREKL
ECDEIYCHYRDPKKFLAEMSMADANFWVDAAALAGIFVGLRIIAYFVLRWKLHSIR

Protein features from InterProScan

Transcript Database ID Name Start End E.value
23 g6039.t1 CDD cd03213 ABCG_EPDR 93 317 1.24839E-93
7 g6039.t1 Gene3D G3DSA:3.40.50.300 - 107 325 3.2E-57
4 g6039.t1 PANTHER PTHR48041:SF78 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A-RELATED 84 771 8.0E-278
5 g6039.t1 PANTHER PTHR48041 ABC TRANSPORTER G FAMILY MEMBER 28 84 771 8.0E-278
3 g6039.t1 Pfam PF00005 ABC transporter 117 263 1.1E-27
1 g6039.t1 Pfam PF19055 ABC-2 type transporter 292 350 3.1E-8
2 g6039.t1 Pfam PF01061 ABC-2 type transporter 503 711 6.0E-45
15 g6039.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 526 -
19 g6039.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 527 544 -
11 g6039.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 545 555 -
18 g6039.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 556 578 -
12 g6039.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 579 597 -
22 g6039.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 598 624 -
10 g6039.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 625 635 -
21 g6039.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 636 660 -
14 g6039.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 661 665 -
17 g6039.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 666 685 -
9 g6039.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 686 696 -
16 g6039.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 697 716 -
13 g6039.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 717 745 -
20 g6039.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 746 768 -
8 g6039.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 769 776 -
31 g6039.t1 ProSitePatterns PS00211 ABC transporters family signature. 235 249 -
33 g6039.t1 ProSiteProfiles PS50893 ATP-binding cassette, ABC transporter-type domain profile. 96 335 20.095
32 g6039.t1 SMART SM00382 AAA_5 126 311 3.9E-11
6 g6039.t1 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 89 317 1.95E-48
24 g6039.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 522 544 -
26 g6039.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 556 578 -
27 g6039.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 604 626 -
25 g6039.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 633 655 -
30 g6039.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 665 687 -
29 g6039.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 694 716 -
28 g6039.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 746 768 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016020 membrane CC
GO:0005524 ATP binding MF
GO:0042626 ATPase-coupled transmembrane transporter activity MF
GO:0016887 ATP hydrolysis activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values