General information for g6125.t22
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphoglycerate kinase.
Parent gene
- The parent gene g6125 is located on chr_2: 14396643..14397863 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6125 | g6125.t22 | TTS | g6125.t22 | 14396087 | 14396087 |
| chr_2 | g6125 | g6125.t22 | isoform | g6125.t22 | 14396253 | 14397863 |
| chr_2 | g6125 | g6125.t22 | exon | g6125.t22.exon1 | 14396253 | 14396278 |
| chr_2 | g6125 | g6125.t22 | cds | g6125.t22.CDS1 | 14396253 | 14396278 |
| chr_2 | g6125 | g6125.t22 | exon | g6125.t22.exon2 | 14396347 | 14396506 |
| chr_2 | g6125 | g6125.t22 | cds | g6125.t22.CDS2 | 14396347 | 14396506 |
| chr_2 | g6125 | g6125.t22 | exon | g6125.t22.exon3 | 14396596 | 14397486 |
| chr_2 | g6125 | g6125.t22 | cds | g6125.t22.CDS3 | 14396596 | 14397486 |
| chr_2 | g6125 | g6125.t22 | exon | g6125.t22.exon4 | 14397771 | 14397863 |
| chr_2 | g6125 | g6125.t22 | cds | g6125.t22.CDS4 | 14397771 | 14397776 |
| chr_2 | g6125 | g6125.t22 | TSS | g6125.t22 | 14397935 | 14397935 |
Sequences
>g6125.t22 Gene=g6125 Length=1170
ATGGCTCTCAACAAATTAAGCATCGAAAACTTGGATTTAGCAGGAAAGCGAGTGTTGATG
CGGTGAGTTTTTAATTTTCCGGTTACAATGGCTGTCTTGTGCTCTCACTTGGGACGACCT
GATGGCAATAAAAATCCAAAATACACCATGGCTCCTGTTGCTGATGAGTTGAAAAAATTG
TTAGGAAAGGATGTCAAATTTATTAATGATTGTGTCGGACCTGAGGTTGAAGCTATTTGT
GCAGATCCACCAACAGGCTCAGTAATTTTGTTGGAAAATCTTCGCTTTTACATTGAAGAA
GAGGGAAAAGGTGTTGATGCAAGTGGTGCTAAAGTGAAGGCAAACGCAGACAAAGTCAAA
GAATTCCGTGCAAGCCTTGCTAAGCTCGGAGACGTCTATATAAATGATGCATTTGGCACA
GCTCATCGTGCTCATTCATCAATGATGGGTGAAGGCTATTCACAACGTGCAGCTGGTTTC
TTGATGAACAAAGAATTGCGTTACTTCTCAAAGGCTCTCGACAACCCAGCACGTCCATTT
TTGGCAATTCTCGGCGGCGCTAAAGTTGCTGACAAAATTCAACTAATTGAGAATTTATTG
GATAAAGTTAATGAAATGATTATTGGTGGTGGAATGGCATTCACTTTTTTGAAAGTATTG
AACAATATGGAAATTGGTGGCTCATTGTTTGACGAGGAAGGCGCCAAAATTGTACAAAAC
TTAGTCGAGAAGGCAAAGAAAAATAATGTGCAGCTTCATTTGCCAGTCGATTTTGTTACT
GGTTCAAAGTTCGGTGAAGACGCTGAAGTTGGCGAAGCATCAGTTGAAAGTGGAATTCCT
GCAGGATGGATGGGACTTGATGTTGGTCCGAAGACTCGTGAGCTATTTGCTGCTCCAGTC
GCTCGTGCAAAGGTCATCGTTTGGAATGGTCCATGTGGTGTTTTTGAATTCCCTAATTTT
GCAAAAGGAACAAAAGCTTTGATGGATGCTGTTGTAGATGTAACTGCTAAAGGAGCTATT
ACAATTATTGGTGGAGGTGATACAGCAAGTTGCTGTGCAAAGTGGGGAACAGAATCTAAA
GTCTCTCATGTTTCAACTGGTGGTGGTGCAAGTTTGGAATTACTCGAAGGAAAAACTTTA
CCAGGTGTTGCTGCATTATCAAATGCTTAA
>g6125.t22 Gene=g6125 Length=360
MAVLCSHLGRPDGNKNPKYTMAPVADELKKLLGKDVKFINDCVGPEVEAICADPPTGSVI
LLENLRFYIEEEGKGVDASGAKVKANADKVKEFRASLAKLGDVYINDAFGTAHRAHSSMM
GEGYSQRAAGFLMNKELRYFSKALDNPARPFLAILGGAKVADKIQLIENLLDKVNEMIIG
GGMAFTFLKVLNNMEIGGSLFDEEGAKIVQNLVEKAKKNNVQLHLPVDFVTGSKFGEDAE
VGEASVESGIPAGWMGLDVGPKTRELFAAPVARAKVIVWNGPCGVFEFPNFAKGTKALMD
AVVDVTAKGAITIIGGGDTASCCAKWGTESKVSHVSTGGGASLELLEGKTLPGVAALSNA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g6125.t22 | CDD | cd00318 | Phosphoglycerate_kinase | 3 | 359 | 0 |
| 12 | g6125.t22 | Gene3D | G3DSA:3.40.50.1260 | - | 19 | 359 | 0 |
| 13 | g6125.t22 | Gene3D | G3DSA:3.40.50.1260 | - | 146 | 335 | 0 |
| 2 | g6125.t22 | PANTHER | PTHR11406:SF0 | PHOSPHOGLYCERATE KINASE | 3 | 359 | 0 |
| 3 | g6125.t22 | PANTHER | PTHR11406 | PHOSPHOGLYCERATE KINASE | 3 | 359 | 0 |
| 14 | g6125.t22 | PIRSF | PIRSF000724 | Pgk | 1 | 360 | 0 |
| 10 | g6125.t22 | PRINTS | PR00477 | Phosphoglycerate kinase family signature | 57 | 72 | 0 |
| 4 | g6125.t22 | PRINTS | PR00477 | Phosphoglycerate kinase family signature | 100 | 122 | 0 |
| 9 | g6125.t22 | PRINTS | PR00477 | Phosphoglycerate kinase family signature | 129 | 151 | 0 |
| 6 | g6125.t22 | PRINTS | PR00477 | Phosphoglycerate kinase family signature | 152 | 171 | 0 |
| 8 | g6125.t22 | PRINTS | PR00477 | Phosphoglycerate kinase family signature | 276 | 301 | 0 |
| 7 | g6125.t22 | PRINTS | PR00477 | Phosphoglycerate kinase family signature | 312 | 323 | 0 |
| 5 | g6125.t22 | PRINTS | PR00477 | Phosphoglycerate kinase family signature | 335 | 352 | 0 |
| 1 | g6125.t22 | Pfam | PF00162 | Phosphoglycerate kinase | 2 | 349 | 0 |
| 11 | g6125.t22 | SUPERFAMILY | SSF53748 | Phosphoglycerate kinase | 2 | 359 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006096 | glycolytic process | BP |
| GO:0004618 | phosphoglycerate kinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
