General information for g6172.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldo-keto reductase family 1 member B10.
Parent gene
- The parent gene g6172 is located on chr_2: 14786169..14787954 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6172 | g6172.t1 | TTS | g6172.t1 | 14786057 | 14786057 |
| chr_2 | g6172 | g6172.t1 | isoform | g6172.t1 | 14786169 | 14787954 |
| chr_2 | g6172 | g6172.t1 | exon | g6172.t1.exon1 | 14786169 | 14786217 |
| chr_2 | g6172 | g6172.t1 | cds | g6172.t1.CDS1 | 14786169 | 14786217 |
| chr_2 | g6172 | g6172.t1 | exon | g6172.t1.exon2 | 14786286 | 14786532 |
| chr_2 | g6172 | g6172.t1 | cds | g6172.t1.CDS2 | 14786286 | 14786532 |
| chr_2 | g6172 | g6172.t1 | exon | g6172.t1.exon3 | 14786607 | 14786767 |
| chr_2 | g6172 | g6172.t1 | cds | g6172.t1.CDS3 | 14786607 | 14786767 |
| chr_2 | g6172 | g6172.t1 | exon | g6172.t1.exon4 | 14786848 | 14787281 |
| chr_2 | g6172 | g6172.t1 | cds | g6172.t1.CDS4 | 14786848 | 14787281 |
| chr_2 | g6172 | g6172.t1 | exon | g6172.t1.exon5 | 14787886 | 14787954 |
| chr_2 | g6172 | g6172.t1 | cds | g6172.t1.CDS5 | 14787886 | 14787954 |
| chr_2 | g6172 | g6172.t1 | TSS | g6172.t1 | NA | NA |
Sequences
>g6172.t1 Gene=g6172 Length=960
ATGTCTGTACCTTCTGTTGAGTTATCAAATGGCTTTAAAATTCCTATGTTAGGACTTGGA
ACTTGGTTGTCACCTGTAGGTCAAGTTGAACAAGCTGTAAAAGATGCGATTGATGCAGGA
TATCGCCACATTGATGGAGCTTATGTTTATCGCAATGAAGCTGAAGTTGGTAATGCAATA
GCTGCAAAGATTGATGAAGGAATTGTGACTCGTGAGGAGCTTTTTGTGACCTCAAAATTA
TGGAATATTTTTCATGATCCAAAACATGTTAGAGGAGCATTAGAGAAAACTTTGCAGGAT
TTGAAACTGAATTATATTGATCTTTATTTGATTCATTTTCCTATGGGCTTGAAATTCATA
GATAGTGAGACATTGAGTCCAAAAACTGAAAATGGTGAATGGATGATTGATACCATTGAT
CATGCTGAAACTTGGAAAGCAATGGAAGAACTTGTTGATGAAGGACTTGTAATATCTATT
GGATTGTCGAATTTCAATTCTAAGCAAATTGAATACATTTTGAGCAATGCAAATATTAAA
CCAGTAATGTTGCAGTGTGAATGCCATCCATACTTGAATCAGAAGAAACTAATCGAATTT
TGTCATGAAAAAGGCATTGCATTTACTGCTTATTCGCCATTGGGTTCAAATTCGCGTCCA
TCTGCAAAACCTGATGATCCGCAACTAATGGAAGATCCAACAATTCTACAGATCAGTGAA
AAACATTCAAAAACTCCAGCTCAAATTTTATTACGCTGGCAAATTCAACGCGGTGTTATT
GCGATCCCAAAATCAGTCACAAAATCTCGAATCATCAGCAATTTTGATATTTTCGATTTC
GAACTTGATGAAGAAGACATGGAAAATATTGATGGATTGAACCGTAATGAAAGATTGATT
GCATTTAAAGATCTCAGACATCACCCAAACTATCCTTTTGGATCGAACGTAGAATTTTAA
>g6172.t1 Gene=g6172 Length=319
MSVPSVELSNGFKIPMLGLGTWLSPVGQVEQAVKDAIDAGYRHIDGAYVYRNEAEVGNAI
AAKIDEGIVTREELFVTSKLWNIFHDPKHVRGALEKTLQDLKLNYIDLYLIHFPMGLKFI
DSETLSPKTENGEWMIDTIDHAETWKAMEELVDEGLVISIGLSNFNSKQIEYILSNANIK
PVMLQCECHPYLNQKKLIEFCHEKGIAFTAYSPLGSNSRPSAKPDDPQLMEDPTILQISE
KHSKTPAQILLRWQIQRGVIAIPKSVTKSRIISNFDIFDFELDEEDMENIDGLNRNERLI
AFKDLRHHPNYPFGSNVEF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g6172.t1 | Gene3D | G3DSA:3.20.20.100 | - | 1 | 317 | 5.5E-135 |
| 2 | g6172.t1 | PANTHER | PTHR11732:SF482 | ZGC:56622 | 5 | 313 | 1.3E-125 |
| 3 | g6172.t1 | PANTHER | PTHR11732 | ALDO/KETO REDUCTASE | 5 | 313 | 1.3E-125 |
| 13 | g6172.t1 | PIRSF | PIRSF000097 | AKR | 1 | 317 | 2.4E-132 |
| 4 | g6172.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 36 | 60 | 1.9E-56 |
| 6 | g6172.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 96 | 114 | 1.9E-56 |
| 7 | g6172.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 148 | 165 | 1.9E-56 |
| 5 | g6172.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 182 | 211 | 1.9E-56 |
| 8 | g6172.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 229 | 253 | 1.9E-56 |
| 1 | g6172.t1 | Pfam | PF00248 | Aldo/keto reductase family | 17 | 294 | 2.7E-52 |
| 10 | g6172.t1 | ProSitePatterns | PS00798 | Aldo/keto reductase family signature 1. | 40 | 57 | - |
| 11 | g6172.t1 | ProSitePatterns | PS00063 | Aldo/keto reductase family putative active site signature. | 262 | 277 | - |
| 9 | g6172.t1 | SUPERFAMILY | SSF51430 | NAD(P)-linked oxidoreductase | 7 | 313 | 5.89E-101 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0047834 | D-threo-aldose 1-dehydrogenase activity | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed