General information for g6244.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glutathione S-transferase 1-1.
Parent gene
- The parent gene g6244 is located on chr_2: 15599048..15602952 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6244 | g6244.t4 | TSS | g6244.t4 | 15598286 | 15598286 |
| chr_2 | g6244 | g6244.t4 | isoform | g6244.t4 | 15598348 | 15599310 |
| chr_2 | g6244 | g6244.t4 | exon | g6244.t4.exon1 | 15598348 | 15599310 |
| chr_2 | g6244 | g6244.t4 | cds | g6244.t4.CDS1 | 15598467 | 15599048 |
| chr_2 | g6244 | g6244.t4 | TTS | g6244.t4 | NA | NA |
Sequences
>g6244.t4 Gene=g6244 Length=963
ATGTGTGATTTATATTATACACCCGGTAAGTGTGTGTGAATAAAAATCGAAATATTGATA
AGATAAAAAATTGATTTTTTTGAAAATTTTTAGCGTCTGGACCTTGTAGAGTGGTTCAGA
TGGTAGCACATGCATTGAAAGTGAAACTCAATTTGAAGCCATTAAACCTTCAACAAAAAG
AACATCTTGCACCAGAATTTTTAAAACTCAATCCACAACATACAGTTCCGACTCTTGTCG
ACAATAATTTTGCACTTTGGGAATCACGTCCGATTGCAATTTATTTGGTGGAAAAATACG
CAAAAGATGATTCACTTTATCCGAAGAATGCAAAACAACGAGCTGTGGTGAATCAACAAT
TATATTTTGACATGGGAACACTTTCAAAACGAATGTATGATTTTTTCTATCCACAATTAA
TGCAAAATGCTGAGGCTGATCCAAAAAAGTTCAAAGAACTTGAAGAAGCTGTTGAATTTT
TGGAAACAAGTTTAAGCAAATCAACATATGCAGCGGGTGAAAAGTTAACAATTGCTGATT
TTGCGTTAGCAGTAACAACAAGCATGTGTGTATTGACTGGTTATGATCTCAGCAAATATT
CCAACATTACACGATGGTATCAATTAATGAAAGATGAATTACCTGGTTGGGAAATTAATG
AAGAAGGATTAAATGTGATGAGACAATATATGAAGAAATAAAAGTTGTATTTATTACGGG
TAAATAAATTAAAAATCACAAGAAATGTTTTGAATCTCTATCTAAGTTACTTTTTTCATT
ATGAACACTGTATATTAACAATCTCTATTTGATTTGTCTTACCTTGATGTATTTAGTCAC
AAATATCTTATTAAATCACTCTAAACTATTAAACTTCTGAATTTTCTTTAATTTAATGCT
TTGTTTGCTTTTGCAAAAATGTAAATTATTTTAAATTTCAACCGTTACATTCAATTTTCA
TTT
>g6244.t4 Gene=g6244 Length=193
MVAHALKVKLNLKPLNLQQKEHLAPEFLKLNPQHTVPTLVDNNFALWESRPIAIYLVEKY
AKDDSLYPKNAKQRAVVNQQLYFDMGTLSKRMYDFFYPQLMQNAEADPKKFKELEEAVEF
LETSLSKSTYAAGEKLTIADFALAVTTSMCVLTGYDLSKYSNITRWYQLMKDELPGWEIN
EEGLNVMRQYMKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g6244.t4 | CDD | cd03177 | GST_C_Delta_Epsilon | 72 | 185 | 0.000 |
| 8 | g6244.t4 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 64 | 0.000 |
| 7 | g6244.t4 | Gene3D | G3DSA:1.20.1050.10 | - | 65 | 193 | 0.000 |
| 3 | g6244.t4 | PANTHER | PTHR43969:SF9 | GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED | 1 | 192 | 0.000 |
| 4 | g6244.t4 | PANTHER | PTHR43969 | GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED | 1 | 192 | 0.000 |
| 2 | g6244.t4 | Pfam | PF02798 | Glutathione S-transferase, N-terminal domain | 3 | 57 | 0.000 |
| 1 | g6244.t4 | Pfam | PF00043 | Glutathione S-transferase, C-terminal domain | 101 | 169 | 0.000 |
| 10 | g6244.t4 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 1 | 64 | 16.969 |
| 9 | g6244.t4 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 70 | 193 | 20.075 |
| 12 | g6244.t4 | SFLD | SFLDG00358 | Main (cytGST) | 1 | 171 | 0.000 |
| 13 | g6244.t4 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 1 | 171 | 0.000 |
| 5 | g6244.t4 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 2 | 69 | 0.000 |
| 6 | g6244.t4 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 55 | 177 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
