Gene loci information

Transcript annotation

  • This transcript has been annotated as DNA replication licensing factor Mcm7.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6252 g6252.t2 TSS g6252.t2 15616922 15616922
chr_2 g6252 g6252.t2 isoform g6252.t2 15617769 15618965
chr_2 g6252 g6252.t2 exon g6252.t2.exon1 15617769 15617799
chr_2 g6252 g6252.t2 cds g6252.t2.CDS1 15617769 15617799
chr_2 g6252 g6252.t2 exon g6252.t2.exon2 15617858 15618965
chr_2 g6252 g6252.t2 cds g6252.t2.CDS2 15617858 15618963
chr_2 g6252 g6252.t2 TTS g6252.t2 NA NA

Sequences

>g6252.t2 Gene=g6252 Length=1139
ATGGCTGGAAGAAATTATTCTGAAGATGTTGAGACCATTAAAAATTTTCTAACTGAATTC
TGCTCAAGCGATGATGAAGGAAACAAGATTTTTAAGTATGCCTCTCAGCTTATTCGCTTA
GCTCATCGTGAGCAAGTAAACATCACAATTGATTTAGATGATTTAGCAGATTATGATGAA
ACTCTCGCTCAAGCCATTCAACAAAATACTCGTCGTTATGCTATCATGTTCTCAAACGTT
ATTCAAGAGCTTCTACCAAACTATAAAGAACGTGAAGTTGTTGCAAAAGATTCACTTGAT
GTCTATATTGAACATCGTATGCTAATGGAGTCTCGATCAAGAAATCCAATGGAACAAAGA
GATCCTCGCAATTCATTTCCACCGGAACTTATGAGACGCTTCGAAGTTTCATTTAAAGCA
TCAAATACAACAAAAGCACTTTCTGTTCGTGAAATTAAAGCCGAACATATTGGCAAATTG
ATGACAGTTCGTGGTATTGTAACAAGATGTACTGAAGTAAAACCAATGATGATTGTCGCT
ACATATACTTGCGACCGCTGTGGAGCAGAAACATATCAACCAGTTAATTCAATGGCTTTT
TTGCCTGTTACTGATTGTCCTTCAGAAGATTGCCGTGTCAATAAAGCAGGTGGTCGTTTG
TATTTGCAAACTCGTGGCAGTAAATTCGTGAAATTCCAAGAAGTGAAAATTCAAGAACAC
AGCGATCAAGTACCAGTTGGTCACATTCCACGAACACTCACGATTGCTTGTCGTGGTGAG
CAAACAAGAAATTGTCAACCAGGTGATCACGTTTTGATTACTGGTGTTTTTTTACCAAAA
CAACGTCATGGATATAGACAAATGCAAAGTGGTCTTTTGAATGAAACTTTTATGGAAGCT
CATCGCATTGTTGCGCTCAATAAATCTGATGAAACTGAATCATTATCAAATGACCTCACA
CCAGAGGAAATTCAAGAACTCTCAAGGGATGATTTTTATACAAGAATGGCTTCAAGTTTA
GCTCCTGAGATTTATGGACATTTAGATGTAAAGAAAGCATTACTTCTGTTGCTTATTGGT
GGTGTTGATAAGAGTCCTGATGGTATGAAAATCAGAGGAAATATCAATATTTTGTTAAT

>g6252.t2 Gene=g6252 Length=379
MAGRNYSEDVETIKNFLTEFCSSDDEGNKIFKYASQLIRLAHREQVNITIDLDDLADYDE
TLAQAIQQNTRRYAIMFSNVIQELLPNYKEREVVAKDSLDVYIEHRMLMESRSRNPMEQR
DPRNSFPPELMRRFEVSFKASNTTKALSVREIKAEHIGKLMTVRGIVTRCTEVKPMMIVA
TYTCDRCGAETYQPVNSMAFLPVTDCPSEDCRVNKAGGRLYLQTRGSKFVKFQEVKIQEH
SDQVPVGHIPRTLTIACRGEQTRNCQPGDHVLITGVFLPKQRHGYRQMQSGLLNETFMEA
HRIVALNKSDETESLSNDLTPEEIQELSRDDFYTRMASSLAPEIYGHLDVKKALLLLLIG
GVDKSPDGMKIRGNINILL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g6252.t2 Gene3D G3DSA:3.30.1640.10 - 5 107 0.000
16 g6252.t2 Gene3D G3DSA:2.40.50.140 - 149 288 0.000
14 g6252.t2 Gene3D G3DSA:2.20.28.10 - 179 226 0.000
13 g6252.t2 Gene3D G3DSA:3.40.50.300 - 320 379 0.000
4 g6252.t2 PANTHER PTHR11630 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER 40 379 0.000
5 g6252.t2 PANTHER PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM7 40 379 0.000
10 g6252.t2 PRINTS PR01663 Mini-chromosome maintenance (MCM) protein 7 signature 126 138 0.000
6 g6252.t2 PRINTS PR01663 Mini-chromosome maintenance (MCM) protein 7 signature 164 175 0.000
9 g6252.t2 PRINTS PR01663 Mini-chromosome maintenance (MCM) protein 7 signature 182 193 0.000
8 g6252.t2 PRINTS PR01663 Mini-chromosome maintenance (MCM) protein 7 signature 199 211 0.000
7 g6252.t2 PRINTS PR01663 Mini-chromosome maintenance (MCM) protein 7 signature 291 301 0.000
3 g6252.t2 Pfam PF14551 MCM N-terminal domain 11 139 0.000
1 g6252.t2 Pfam PF17207 MCM OB domain 149 278 0.000
2 g6252.t2 Pfam PF00493 MCM P-loop domain 322 379 0.000
17 g6252.t2 ProSiteProfiles PS50051 MCM family domain profile. 332 379 18.852
12 g6252.t2 SMART SM00350 mcm 145 379 0.000
11 g6252.t2 SUPERFAMILY SSF50249 Nucleic acid-binding proteins 18 300 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003677 DNA binding MF
GO:0005524 ATP binding MF
GO:0042555 MCM complex CC
GO:0006270 DNA replication initiation BP
GO:0032508 DNA duplex unwinding BP
GO:0003678 DNA helicase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values