General information for g6312.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldose 1-epimerase.
Parent gene
- The parent gene g6312 is located on chr_2: 16130631..16131522 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6312 | g6312.t1 | TTS | g6312.t1 | 16128925 | 16128925 |
| chr_2 | g6312 | g6312.t1 | isoform | g6312.t1 | 16128961 | 16131522 |
| chr_2 | g6312 | g6312.t1 | exon | g6312.t1.exon1 | 16128961 | 16129041 |
| chr_2 | g6312 | g6312.t1 | cds | g6312.t1.CDS1 | 16128961 | 16129041 |
| chr_2 | g6312 | g6312.t1 | exon | g6312.t1.exon2 | 16129100 | 16129312 |
| chr_2 | g6312 | g6312.t1 | cds | g6312.t1.CDS2 | 16129100 | 16129312 |
| chr_2 | g6312 | g6312.t1 | exon | g6312.t1.exon3 | 16129489 | 16129588 |
| chr_2 | g6312 | g6312.t1 | cds | g6312.t1.CDS3 | 16129489 | 16129588 |
| chr_2 | g6312 | g6312.t1 | exon | g6312.t1.exon4 | 16130622 | 16130872 |
| chr_2 | g6312 | g6312.t1 | cds | g6312.t1.CDS4 | 16130622 | 16130872 |
| chr_2 | g6312 | g6312.t1 | exon | g6312.t1.exon5 | 16130935 | 16131522 |
| chr_2 | g6312 | g6312.t1 | cds | g6312.t1.CDS5 | 16130935 | 16131522 |
| chr_2 | g6312 | g6312.t1 | TSS | g6312.t1 | 16131561 | 16131561 |
Sequences
>g6312.t1 Gene=g6312 Length=1233
ATGACAAGCCGCGGAGTGACTTTAAAAGTTGATTCTTTTGGTTCTGTTGAAGATCCAATT
TCAAAGAAACTTGAGGAAATTTCACGATTTACTTGGCAAAATGAGAATGGAATGATTGTG
CAATTAATAAGTTATGGAGCAATTTTGACTTCAATTAAAGTTCCAGATCGGACAGGACAA
TTATCTGATGTAGTCCTTGGATTTGATGATATTGATGGCTATAGAAAGAAAAATAATCCT
TATTTTGGTGCTCTTGTTGGTCGTGTTGCTAATAGAATTGCTAGAGGTCAATTTATTCTC
AATGGTGAAGTCATAAATGTTGCAAAAAATTGGAATAACAAACATGCATTACATGGAGGA
ATTATTGGTTTTGATAAGTTTAATTTTCATCATTTTATTGATGGAAATGTTGTCTATCTT
ACAAGTCTATCGCTAGATAAATTTGAAGGCTATCCAGGCGATGTCATTACAACTGTAAAA
TGTGAACTACTCAGTGACAATTCTCTCACAATGGAATTTACTGCAACCACAACAAAACCA
ACCGCAATCAATTTAACCAATCATTCTTATTTTAATCTCGCTGGTCATGAGACTGGTTAT
GAAGAAATTTACAAGCATGTTATATCAATTAATGCTGATAAGATAACAGAGACTGATCAT
GAATCGATACCAACTGGTAATTTTATTTCGGTTGGTGGAACTGCTTTTGATTTGAGAATA
CCAAAAGAACTTGGGCCAGCAATGAGGAATTTATCTGGACCAGGATATGATGACAATTTT
TGTGTTAATGTGCCAAAGGGAAAAGATGGTGATGAACAGCCGATTGTATTTGTTTCAAGA
GTTGTTCATCCTACAAGTGGTCGATATTTAGAAATATTCAGTAATCAACCAGGAGTTCAG
CTGTATACTTCCAATTTTTTGCCTGATCCATGTGGAAATATTAAGCCATCATCAAATGAA
GAATATTATGAAGTCGATGGAATGTTGACAACAAGACTTGAGCAAGTTGATGTGACAACA
AAGGAAAAGAAAATTCCAAAATGTACTGAAACTAACGATGAAAATGCTGTAATTGGAAAA
GGTGGAGTTCGTTATTACAAACATGGAGCTTTTTGCTTTGAAACTCAGAAATTTCCTGAC
GCTGTTCATCATACCAATTTTCCGTCAGTAATTTTGAACCCAGGAAAAATTTACAAACAT
GAAGTTATTTACAAATTTGGAATTGAAGCCTAA
>g6312.t1 Gene=g6312 Length=410
MTSRGVTLKVDSFGSVEDPISKKLEEISRFTWQNENGMIVQLISYGAILTSIKVPDRTGQ
LSDVVLGFDDIDGYRKKNNPYFGALVGRVANRIARGQFILNGEVINVAKNWNNKHALHGG
IIGFDKFNFHHFIDGNVVYLTSLSLDKFEGYPGDVITTVKCELLSDNSLTMEFTATTTKP
TAINLTNHSYFNLAGHETGYEEIYKHVISINADKITETDHESIPTGNFISVGGTAFDLRI
PKELGPAMRNLSGPGYDDNFCVNVPKGKDGDEQPIVFVSRVVHPTSGRYLEIFSNQPGVQ
LYTSNFLPDPCGNIKPSSNEEYYEVDGMLTTRLEQVDVTTKEKKIPKCTETNDENAVIGK
GGVRYYKHGAFCFETQKFPDAVHHTNFPSVILNPGKIYKHEVIYKFGIEA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g6312.t1 | CDD | cd09019 | galactose_mutarotase_like | 29 | 406 | 3.63737E-142 |
| 2 | g6312.t1 | PANTHER | PTHR10091:SF0 | ALDOSE 1-EPIMERASE | 20 | 407 | 5.8E-116 |
| 3 | g6312.t1 | PANTHER | PTHR10091 | ALDOSE-1-EPIMERASE | 20 | 407 | 5.8E-116 |
| 7 | g6312.t1 | PIRSF | PIRSF005096 | GALM | 15 | 321 | 9.7E-85 |
| 6 | g6312.t1 | PIRSF | PIRSF005096 | GALM | 330 | 409 | 9.4E-15 |
| 1 | g6312.t1 | Pfam | PF01263 | Aldose 1-epimerase | 29 | 405 | 4.4E-80 |
| 5 | g6312.t1 | ProSitePatterns | PS00545 | Aldose 1-epimerase putative active site. | 184 | 193 | - |
| 4 | g6312.t1 | SUPERFAMILY | SSF74650 | Galactose mutarotase-like | 25 | 406 | 1.17E-99 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0030246 | carbohydrate binding | MF |
| GO:0016853 | isomerase activity | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0019318 | hexose metabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K01785 (aldose 1-epimerase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
