Gene loci information

Transcript annotation

  • This transcript has been annotated as Aldose 1-epimerase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6312 g6312.t3 TTS g6312.t3 16128925 16128925
chr_2 g6312 g6312.t3 isoform g6312.t3 16129102 16131522
chr_2 g6312 g6312.t3 exon g6312.t3.exon1 16129102 16129312
chr_2 g6312 g6312.t3 cds g6312.t3.CDS1 16129103 16129312
chr_2 g6312 g6312.t3 exon g6312.t3.exon2 16129489 16129588
chr_2 g6312 g6312.t3 cds g6312.t3.CDS2 16129489 16129588
chr_2 g6312 g6312.t3 exon g6312.t3.exon3 16130622 16130872
chr_2 g6312 g6312.t3 cds g6312.t3.CDS3 16130622 16130872
chr_2 g6312 g6312.t3 exon g6312.t3.exon4 16130935 16131522
chr_2 g6312 g6312.t3 cds g6312.t3.CDS4 16130935 16131522
chr_2 g6312 g6312.t3 TSS g6312.t3 16131561 16131561

Sequences

>g6312.t3 Gene=g6312 Length=1150
ATGACAAGCCGCGGAGTGACTTTAAAAGTTGATTCTTTTGGTTCTGTTGAAGATCCAATT
TCAAAGAAACTTGAGGAAATTTCACGATTTACTTGGCAAAATGAGAATGGAATGATTGTG
CAATTAATAAGTTATGGAGCAATTTTGACTTCAATTAAAGTTCCAGATCGGACAGGACAA
TTATCTGATGTAGTCCTTGGATTTGATGATATTGATGGCTATAGAAAGAAAAATAATCCT
TATTTTGGTGCTCTTGTTGGTCGTGTTGCTAATAGAATTGCTAGAGGTCAATTTATTCTC
AATGGTGAAGTCATAAATGTTGCAAAAAATTGGAATAACAAACATGCATTACATGGAGGA
ATTATTGGTTTTGATAAGTTTAATTTTCATCATTTTATTGATGGAAATGTTGTCTATCTT
ACAAGTCTATCGCTAGATAAATTTGAAGGCTATCCAGGCGATGTCATTACAACTGTAAAA
TGTGAACTACTCAGTGACAATTCTCTCACAATGGAATTTACTGCAACCACAACAAAACCA
ACCGCAATCAATTTAACCAATCATTCTTATTTTAATCTCGCTGGTCATGAGACTGGTTAT
GAAGAAATTTACAAGCATGTTATATCAATTAATGCTGATAAGATAACAGAGACTGATCAT
GAATCGATACCAACTGGTAATTTTATTTCGGTTGGTGGAACTGCTTTTGATTTGAGAATA
CCAAAAGAACTTGGGCCAGCAATGAGGAATTTATCTGGACCAGGATATGATGACAATTTT
TGTGTTAATGTGCCAAAGGGAAAAGATGGTGATGAACAGCCGATTGTATTTGTTTCAAGA
GTTGTTCATCCTACAAGTGGTCGATATTTAGAAATATTCAGTAATCAACCAGGAGTTCAG
CTGTATACTTCCAATTTTTTGCCTGATCCATGTGGAAATATTAAGCCATCATCAAATGAA
GAATATTATGAAGTCGATGGAATGTTGACAACAAGACTTGAGCAAGTTGATGTGACAACA
AAGGAAAAGAAAATTCCAAAATGTACTGAAACTAACGATGAAAATGCTGTAATTGGAAAA
GGTGGAGTTCGTTATTACAAACATGGAGCTTTTTGCTTTGAAACTCAGAAATTTCCTGAC
GCTGTTCATC

>g6312.t3 Gene=g6312 Length=383
MTSRGVTLKVDSFGSVEDPISKKLEEISRFTWQNENGMIVQLISYGAILTSIKVPDRTGQ
LSDVVLGFDDIDGYRKKNNPYFGALVGRVANRIARGQFILNGEVINVAKNWNNKHALHGG
IIGFDKFNFHHFIDGNVVYLTSLSLDKFEGYPGDVITTVKCELLSDNSLTMEFTATTTKP
TAINLTNHSYFNLAGHETGYEEIYKHVISINADKITETDHESIPTGNFISVGGTAFDLRI
PKELGPAMRNLSGPGYDDNFCVNVPKGKDGDEQPIVFVSRVVHPTSGRYLEIFSNQPGVQ
LYTSNFLPDPCGNIKPSSNEEYYEVDGMLTTRLEQVDVTTKEKKIPKCTETNDENAVIGK
GGVRYYKHGAFCFETQKFPDAVH

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g6312.t3 CDD cd09019 galactose_mutarotase_like 29 383 1.11252E-127
2 g6312.t3 PANTHER PTHR10091:SF0 ALDOSE 1-EPIMERASE 20 382 4.4E-106
3 g6312.t3 PANTHER PTHR10091 ALDOSE-1-EPIMERASE 20 382 4.4E-106
7 g6312.t3 PIRSF PIRSF005096 GALM 15 328 6.9E-85
6 g6312.t3 PIRSF PIRSF005096 GALM 324 383 1.2E-4
1 g6312.t3 Pfam PF01263 Aldose 1-epimerase 29 383 3.3E-71
5 g6312.t3 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 184 193 -
4 g6312.t3 SUPERFAMILY SSF74650 Galactose mutarotase-like 25 383 2.09E-90

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0030246 carbohydrate binding MF
GO:0016853 isomerase activity MF
GO:0005975 carbohydrate metabolic process BP
GO:0003824 catalytic activity MF
GO:0019318 hexose metabolic process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values