General information for g635.t19
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial.
Parent gene
- The parent gene g635 is located on chr_3: 4682651..4683238 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g635 | g635.t19 | isoform | g635.t19 | 4682241 | 4683238 |
| chr_3 | g635 | g635.t19 | exon | g635.t19.exon1 | 4682241 | 4682439 |
| chr_3 | g635 | g635.t19 | cds | g635.t19.CDS1 | 4682302 | 4682439 |
| chr_3 | g635 | g635.t19 | exon | g635.t19.exon2 | 4682523 | 4683238 |
| chr_3 | g635 | g635.t19 | cds | g635.t19.CDS2 | 4682523 | 4682657 |
| chr_3 | g635 | g635.t19 | TTS | g635.t19 | 4683211 | 4683211 |
| chr_3 | g635 | g635.t19 | TSS | g635.t19 | NA | NA |
Sequences
>g635.t19 Gene=g635 Length=915
TGAATTGGGTATCAATGCTTTGGGCGAGAAAGCTCGTAATGGAACATTAGCTGTTGAAGA
TATGGACGGTGGTACTTTTACAATCAGTAATGGAGGCGTATTTGGTTCACTAATGGGTAC
TCCAATTATTAATCCACCACAAAGTGCTATTCTCGGTATGCACGCAACATTTGAGCGACC
AGTGGCTATCAAAGGACAAGTCGTTATTCGTCCCATGATGTACATCGCACTTACGTATGA
TCATCGTTTGATTGATGGACGTGAGGCTGTGACTTTCTTGCGTAAAATCAAAGCAGGTGT
CGAAGATCCAAGAATCATCTTGGCTGGCGTTTAAATAATTAACTGAAATGCTTGCACTAT
ACGAGCGCATCGGACATACAAAAAACAATATTTTTCGGTGAAATTTACTTACACTTAGGG
CATATCTTTTTTTCTTCATTTGAACAATTCGACTTCAATAATAAAACCACAAGATGAATC
TTTAAAATGTTAATTTAATAGTAAAAAAAGAATAAGCCGAGAGATAAAGATAAATTATTG
ACATAAACAAAAAACACTCGAGAGAAAGTAATTTGTATTAATGATGTGCACCATCGAGTT
TATATAAGTTGAATATCAAAATCTGATCTATATCTATTGATGATAATAGACAAGACATTA
TCTACCTATTGATTATTATTATTAACTATATACGAATCTTTATTGCAATTCAATTTTGGC
CGAGAAATGAAAGAAAAACCTCAACTCATTTCCCTAAATAATTTTTTTTGTGAAAAAATC
GAAAAAGAGGATAAATGCAGGATAGCGTCATAAAAATCACATTTAGTTCGACAACAATAA
AATAATTTATTTAAAGTTTTAAAATAAAAAAAATAATTTGCAAAAATAAAGAAAAACTTT
TTAAGAATCAAAATG
>g635.t19 Gene=g635 Length=90
MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHATFERPVAIKGQVVIRPMMYIALTYD
HRLIDGREAVTFLRKIKAGVEDPRIILAGV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g635.t19 | Gene3D | G3DSA:3.30.559.10 | Chloramphenicol Acetyltransferase | 1 | 89 | 0 |
| 2 | g635.t19 | PANTHER | PTHR43416 | DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED | 1 | 87 | 0 |
| 3 | g635.t19 | PANTHER | PTHR43416:SF18 | DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL | 1 | 87 | 0 |
| 1 | g635.t19 | Pfam | PF00198 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | 1 | 86 | 0 |
| 4 | g635.t19 | SUPERFAMILY | SSF52777 | CoA-dependent acyltransferases | 1 | 87 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016746 | acyltransferase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
