Gene loci information

Transcript annotation

  • This transcript has been annotated as Glutathione S-transferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6397 g6397.t1 TTS g6397.t1 16858118 16858118
chr_2 g6397 g6397.t1 isoform g6397.t1 16859131 16859722
chr_2 g6397 g6397.t1 exon g6397.t1.exon1 16859131 16859298
chr_2 g6397 g6397.t1 cds g6397.t1.CDS1 16859131 16859298
chr_2 g6397 g6397.t1 exon g6397.t1.exon2 16859358 16859500
chr_2 g6397 g6397.t1 cds g6397.t1.CDS2 16859358 16859500
chr_2 g6397 g6397.t1 exon g6397.t1.exon3 16859557 16859722
chr_2 g6397 g6397.t1 cds g6397.t1.CDS3 16859557 16859722
chr_2 g6397 g6397.t1 TSS g6397.t1 NA NA

Sequences

>g6397.t1 Gene=g6397 Length=477
ATGCCAATGGGTCAAATGCCTGTTTTGGAAGTTGACGGAAAGCGTGTTCATCAATCACTC
GCTATGTGCCGCTATGTTGCTAAAGTCGTTGGTGTTGCTGGCAACAATCCATTCGAAGAT
TTACAAATTGATGCTATTGTTGATACCATTAATGAATTTCGTCTTAAAATTGCCATTGTC
TCATATGAGCCAGATGATGCTGTAAAAGAGAAGAAAATGATTACACTAACTCAAGAAGTT
ATCCCATTCTATTTGACAAAATTGAATGTCATTGCAAAAGAGAATGGTGGACATTTGGTG
TTAAACAGAACCACATGGGCTGATATTTATTTTGCTGGAATCATTGACTACTTGAACTAC
TTAACAAAACTTGATTTGCTTGAAAACTTCCCAAATTTGCGTGAAGTTGTCGAGAAAGTT
CTCAGCAACGAAAATATTCAGAAATATATTGCTCAGAGACCAGTCACTGAAGTATAA

>g6397.t1 Gene=g6397 Length=158
MPMGQMPVLEVDGKRVHQSLAMCRYVAKVVGVAGNNPFEDLQIDAIVDTINEFRLKIAIV
SYEPDDAVKEKKMITLTQEVIPFYLTKLNVIAKENGGHLVLNRTTWADIYFAGIIDYLNY
LTKLDLLENFPNLREVVEKVLSNENIQKYIAQRPVTEV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g6397.t1 CDD cd03192 GST_C_Sigma_like 39 140 0.0000000
7 g6397.t1 Gene3D G3DSA:3.40.30.10 Glutaredoxin 1 151 0.0000000
6 g6397.t1 Gene3D G3DSA:1.20.1050.10 - 31 142 0.0000000
2 g6397.t1 PANTHER PTHR11571:SF234 GLUTATHIONE S-TRANSFERASE S1 1 158 0.0000000
3 g6397.t1 PANTHER PTHR11571 GLUTATHIONE S-TRANSFERASE 1 158 0.0000000
1 g6397.t1 Pfam PF14497 Glutathione S-transferase, C-terminal domain 52 153 0.0000000
9 g6397.t1 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 1 34 14.9740000
8 g6397.t1 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 36 158 18.9940000
11 g6397.t1 SFLD SFLDS00019 Glutathione Transferase (cytosolic) 1 142 0.0000000
4 g6397.t1 SUPERFAMILY SSF52833 Thioredoxin-like 1 30 0.0000005
5 g6397.t1 SUPERFAMILY SSF47616 GST C-terminal domain-like 33 157 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed