General information for g642.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Mitochondrial fission 1 protein.
Parent gene
- The parent gene g642 is located on chr_3: 4865775..4872796 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g642 | g642.t1 | TTS | g642.t1 | 4864730 | 4864730 |
| chr_3 | g642 | g642.t1 | isoform | g642.t1 | 4865397 | 4866302 |
| chr_3 | g642 | g642.t1 | exon | g642.t1.exon1 | 4865397 | 4865532 |
| chr_3 | g642 | g642.t1 | cds | g642.t1.CDS1 | 4865397 | 4865532 |
| chr_3 | g642 | g642.t1 | exon | g642.t1.exon2 | 4865592 | 4865704 |
| chr_3 | g642 | g642.t1 | cds | g642.t1.CDS2 | 4865592 | 4865704 |
| chr_3 | g642 | g642.t1 | exon | g642.t1.exon3 | 4865770 | 4865827 |
| chr_3 | g642 | g642.t1 | cds | g642.t1.CDS3 | 4865770 | 4865827 |
| chr_3 | g642 | g642.t1 | exon | g642.t1.exon4 | 4865884 | 4866113 |
| chr_3 | g642 | g642.t1 | cds | g642.t1.CDS4 | 4865884 | 4866113 |
| chr_3 | g642 | g642.t1 | exon | g642.t1.exon5 | 4866222 | 4866302 |
| chr_3 | g642 | g642.t1 | cds | g642.t1.CDS5 | 4866222 | 4866302 |
| chr_3 | g642 | g642.t1 | TSS | g642.t1 | 4866370 | 4866370 |
Sequences
>g642.t1 Gene=g642 Length=618
ATGTTTACTTCATTTAACACTGATAAAAATCGAGATATCGAAGAATTGTTGAGTGACACA
GTGTCAGCACAGGATTTAGAAAAAATCGAGAAAGTTTATATGAAAGAGTTGACAGAAAAG
AAATTTGTATCAGCAAAAACACAATTCGAGTATGCATGGTGTTTAGTAAGAAGCAAATAT
GGTGCAGATATAAATAATGGAATCAAAAATTTTGAATCACTTTGTAAAGATGATCCAGAA
AATAAGAGAGACTACATTTATTACATTGCAATTGGTTATATTCGACTTAAAGACTTACCA
ACAGCACAAAAATATGTGAAAGCTTTCCTTGAAATTGAACCAAATAATCATCAAGTGATT
TTATTAGATGAACATATTGAGACAGAAATGAGAAAAGAATTCAAAAGGGATGCAGCAGTT
GCTGGTGGTGCTTTGTTAGTTTTTGGTGGTTTACTTGGTGTTGGATTTGCTCTTGCTAAA
AATCTTATAATGGGAAAAAGTTTAATTATAACTTTTCTTGATAATTTCGCATGGTTAACA
GTTAAATTTTTATGGAACAATATGGACATAATTGCGAATATAATATGGAAATTTGTCAAA
ATGGGTTTTCTAATTTAA
>g642.t1 Gene=g642 Length=205
MFTSFNTDKNRDIEELLSDTVSAQDLEKIEKVYMKELTEKKFVSAKTQFEYAWCLVRSKY
GADINNGIKNFESLCKDDPENKRDYIYYIAIGYIRLKDLPTAQKYVKAFLEIEPNNHQVI
LLDEHIETEMRKEFKRDAAVAGGALLVFGGLLGVGFALAKNLIMGKSLIITFLDNFAWLT
VKFLWNNMDIIANIIWKFVKMGFLI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g642.t1 | CDD | cd12212 | Fis1 | 20 | 133 | 3.63561E-33 |
| 8 | g642.t1 | Gene3D | G3DSA:1.25.40.10 | - | 13 | 159 | 2.0E-41 |
| 3 | g642.t1 | PANTHER | PTHR13247 | TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 | 7 | 157 | 5.1E-31 |
| 4 | g642.t1 | PANTHER | PTHR13247:SF0 | MITOCHONDRIAL FISSION 1 PROTEIN | 7 | 157 | 5.1E-31 |
| 2 | g642.t1 | Pfam | PF14852 | Fis1 N-terminal tetratricopeptide repeat | 47 | 78 | 2.4E-11 |
| 1 | g642.t1 | Pfam | PF14853 | Fis1 C-terminal tetratricopeptide repeat | 83 | 133 | 6.5E-18 |
| 10 | g642.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 137 | - |
| 13 | g642.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 138 | 159 | - |
| 11 | g642.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 160 | 164 | - |
| 12 | g642.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 165 | 185 | - |
| 9 | g642.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 186 | 205 | - |
| 7 | g642.t1 | SUPERFAMILY | SSF48452 | TPR-like | 14 | 160 | 1.21E-34 |
| 5 | g642.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 140 | 159 | - |
| 6 | g642.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 163 | 185 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0000266 | mitochondrial fission | BP |
KEGG
Orthology
- This transcript has been annotated with K17969 (mitochondrial fission 1 protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
