General information for g6594.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein disabled.
Parent gene
- The parent gene g6594 is located on chr_2: 17741355..17746043 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6594 | g6594.t1 | isoform | g6594.t1 | 17741355 | 17746043 |
| chr_2 | g6594 | g6594.t1 | exon | g6594.t1.exon1 | 17741355 | 17741461 |
| chr_2 | g6594 | g6594.t1 | cds | g6594.t1.CDS1 | 17741355 | 17741461 |
| chr_2 | g6594 | g6594.t1 | exon | g6594.t1.exon2 | 17741547 | 17741687 |
| chr_2 | g6594 | g6594.t1 | cds | g6594.t1.CDS2 | 17741547 | 17741687 |
| chr_2 | g6594 | g6594.t1 | exon | g6594.t1.exon3 | 17741833 | 17744214 |
| chr_2 | g6594 | g6594.t1 | cds | g6594.t1.CDS3 | 17741833 | 17744214 |
| chr_2 | g6594 | g6594.t1 | exon | g6594.t1.exon4 | 17744269 | 17745133 |
| chr_2 | g6594 | g6594.t1 | cds | g6594.t1.CDS4 | 17744269 | 17745133 |
| chr_2 | g6594 | g6594.t1 | exon | g6594.t1.exon5 | 17745229 | 17745443 |
| chr_2 | g6594 | g6594.t1 | cds | g6594.t1.CDS5 | 17745229 | 17745443 |
| chr_2 | g6594 | g6594.t1 | exon | g6594.t1.exon6 | 17746010 | 17746043 |
| chr_2 | g6594 | g6594.t1 | cds | g6594.t1.CDS6 | 17746010 | 17746043 |
| chr_2 | g6594 | g6594.t1 | TSS | g6594.t1 | 17746952 | 17746952 |
| chr_2 | g6594 | g6594.t1 | TTS | g6594.t1 | NA | NA |
Sequences
>g6594.t1 Gene=g6594 Length=3744
ATGCAAACATTAAGAAAGAAGAGTCCATTAAAATATCGAAATGAACCTGCAAGATTTTTT
GGAGATGGGGTTGTATTCAAGGCTAAACTTATTGGTATCTTGGAAGTTGGTGAAGCAAGA
GGCGATAGAATGTGTCAAGAAGCATTGCAGGACTTGAAAATCGCTATAAGAGCTGCAGGC
GAACATAAACAACGCATAACTATTCATGTTACAATCGAAGGACTTCGACTTAGAGATGAA
AAAAGTGGAGAATCACTTTATCATCATCCGGTACATAAAATATCTTTTATAGCTCAAGAT
ATGACTGATTCAAGAGCGTTTGGATACATCTTTGGTTCACCAGATTGCGGGCATAGATTT
TTTGGCATTAAAACGGATAAAGCAGCTAGTCAAGTTGTATTAGCTATGCGTGATTTATTT
CAATGCGTTTTTGAGTTAAAGAAAAAGGAAATTGAGTTAGCCAAGCAACATATTCAAAAT
AGGATCACTGCACATGAACATCAGCAAATAAAAAGTTCTATACTAGAACATAAGAAAAGT
ACGAGCTTACTAAATGAAGCAACAGCGATAACGAGACCGGCATCTAAAGCAGAAAAATCA
CCCGAAGCGACAGCCAATTTAGTAGACTTAGAACAAGAATTGAGCTCGATTCAGCGTGGA
ATTACACAAATGGAAAGAATAACACCAAATGATGATGTTCCTTTAACTGCTATCACTTCA
ACTAAAAATGTACTAGACGATGATCCCTTTGGCGACTCTTTCACAAGTTTCTCATCAACA
ACACCATTTAATATTTTGCCACCTCCAACAGCAGCTGCTAAACGTTCGATAATTTCCACT
AAACAAGTAATTGATGAAGATCCTATTAGTTTAGGAGAATTGTCTTCTATAACTTATAAA
TCCACAACACCACCCATTTTACAATCTCAACCTCAGCAAGTATCAACATTAGATTCATGG
CTACAATCTTCATCGTCCACATCAACAGTGCCATTCGTTGCTACTACTACTGCTCATGCA
TTTAAAGAAAACGATACTATTATAAAAACTGATGAAAATTCCTCAATACGCAGTAATAGC
AGTAGCAGACAATTTCAAGAAGATGATTATGATAATCTAGATCCGCTTGGCAAGAAATCT
TATGTAGATAAAAAATATTTTTTTCAAGACCTTAAAAATCCTCCTAAGAAGGTTTTAAAG
GATTTGACATCAGAACAAGACAGTATTTTCGATGCACATTTCTCACCACTAAAAAGAAAA
AATGAAGAGTCATTGTCTAGTTCACGTGCACATGAAGAAAACTCGCAAATAATTGATCCA
TTTGAAGAGGAAGATTTTTCAAAAATTGTAATAGATCAATTAGAATCAACAACAACACCG
GCAACAGCAACAGCAGTTAGTAAAAAATCAATAATATTACCAGACACAAAGATCAACTCT
ATAACTGAAATTAAATCAAAGAATGAAGAAAAATCACATGAGTATAAAGGATTTAATGTA
GACTTGGATGCAGATTCATCTATTTATTCAACTGCAATATATACAGACTTAAAAAGGCAA
AATTCTGATTCATCCTCGAAAAATGTTTTCTCTGTGGATTCGCTATCCAAAAAACTTCCT
AAAGCTAACTTATTTGGACAACGCAATGTAAAGAGAGATTCAAATGGAATTAACATGAGA
CGACTTCAGGAAAGTGATTCATTAAGTGAAGAAAATGAACCGGAATTACCTCCTCGATTG
CCAGATTCAGAACCACCTCCTTTGCCACCGAAAAATCAAATGAACCAAAAGGATTCAACA
AATGAACTTCAATCTGATCGAAATCGTTATAGCAAAACTTCATCTTCAACGTCACGAGAA
TCAGGTTCACGATACGATTATGCAAATAAATTTAAATCTCATTCAACTGATTCGCCACCT
ATTCCTTTGCCAAGTCGAAAAATCAATAGAGCTGAAACTTCTAGATCTTCAAAAAGATCA
AATGACGATGATGACTATTTGACTCCCAGTGTATCACTATCTTCACAAAACATTAACTCC
ACTATACCACAATTGCCGCCACCTCCTCCACAAAAAAACACCTCGAAACTTCGTGGAACA
CGAAAATCTGAAACTGATCCGAAAAATCTTGATGCACCTACACCACCAGTTTCGGCCAAA
GCAGACTCTTCTGCAACTGCAATCATACCAGATATTACTCTAAGTCAATTATTAACATTA
GGTGTTGATGATTTGGCGCAAAAACTCAACGTACAACCTTCAAAATTAAATACAATGACA
CTTGTCGAATTAACAACTTATTTATCTGAATTTATAGAAAACTCTAAACAATCAAATAAT
GCTGTGCCAACAATGGCACCGCCTCCTCCTCCAATACCCATTCGTCCATCACTTGAAACT
CCAGTAGATTCACCAGTATTTAAAGTTAGTTTTGATGATGCCGTATTTGAAGCAAAATTT
GATGATAATTTTGGTGAATTACAAGAACAATCGAAGCAACAACAACATGAAGAAACAAAC
TCATTTGTAGCTAATTTTGATAACTTTAATCAGGCGCCAGTATCTGTTATACCAACAGCA
GATCGTTATGCTGTATTTCGGGAAATAATTGATCAAGAAATACAAAAACATCAATCATTT
GACGGACATCAAGAATCAATTGAATCAAATAACTCAAACTCTTTGGAAGAAATTCAAGAA
GGAGGATCTTTTGATTTTACAAATGACCAAAATCAAAATGAATCACCACAAGAAAACCAA
TTTCAGCAAAGTCCTATTCCCTATCAAACTCAATGTTCTTCAAAACTTGATAATAAAATA
ACTGAAGCTTTATCTGGCGTTAAAGATCGATATGCTGCCTTACGTGAGCTTCGAAATATA
GTTTTGGTTGAAGACCTTTTTGATAAAAGCCCCAAACCACCATTAGCTTCTATTTCTGAC
TCAAACTTGAGTGACGAAATTTGTGATGATGCATCAAGTTCAAATCAAGGATTTGCTTTA
TTTCCAACAAGCGAAATAATTGAAGATAACTCTATGGAAAATATACCAACATATAATATA
TCGTGGACAAATGATGAAGTTCCCACCGAAACTATAGAAAATATTGTTCAAGAAGAAGAG
CAGCAGCAACAACAGCAATCTTTTGAAGATGAAAGGTTAAGCAAAATTAATAATACTTTA
AACGCTGGAAGCAATAAAGATGATTTGGAAATTGATGAATATATGAATAAGGCTATTTCC
GAATTATCACTTGATCAGCGAATTTCACCTAATATACAAAACAAGTCTCCATCTATTAAA
GCGGAAGATGATGAGACTTTATTAAAACCATCATTGACAGCTTCAACAGAATGCAAAACA
TCAGCTATGGTGTCCATAGAGAATAAATCATCATCACCTATAGCAAGTTCTCTTGTTATA
AAAACAGAATCTTCCAATGAAGCAATGAATAATGAAAAAACTAATAGTGAAATAACAGAA
AAAGAAGAATCTAGAGAAAAAACAATTACTCCTGTTAAACCAATAGAATCTTCAGAATCG
TGGGCTGTATTTGAAGACACTCATATACAAACGAAAATGCCAGAAAAATCTAATATTGGT
GTAGCAAAAGCTGACTTTGAATCAGGTTCATCAGATGCCCATGGGAAGATGGACCAGAGC
ACAGAAAAAGACATCAACATCCTCATTATCATCATTCATCTGAAAGATATTCTCGTCCGC
AAGCACCATCTCGACATAAAATGA
>g6594.t1 Gene=g6594 Length=1247
MQTLRKKSPLKYRNEPARFFGDGVVFKAKLIGILEVGEARGDRMCQEALQDLKIAIRAAG
EHKQRITIHVTIEGLRLRDEKSGESLYHHPVHKISFIAQDMTDSRAFGYIFGSPDCGHRF
FGIKTDKAASQVVLAMRDLFQCVFELKKKEIELAKQHIQNRITAHEHQQIKSSILEHKKS
TSLLNEATAITRPASKAEKSPEATANLVDLEQELSSIQRGITQMERITPNDDVPLTAITS
TKNVLDDDPFGDSFTSFSSTTPFNILPPPTAAAKRSIISTKQVIDEDPISLGELSSITYK
STTPPILQSQPQQVSTLDSWLQSSSSTSTVPFVATTTAHAFKENDTIIKTDENSSIRSNS
SSRQFQEDDYDNLDPLGKKSYVDKKYFFQDLKNPPKKVLKDLTSEQDSIFDAHFSPLKRK
NEESLSSSRAHEENSQIIDPFEEEDFSKIVIDQLESTTTPATATAVSKKSIILPDTKINS
ITEIKSKNEEKSHEYKGFNVDLDADSSIYSTAIYTDLKRQNSDSSSKNVFSVDSLSKKLP
KANLFGQRNVKRDSNGINMRRLQESDSLSEENEPELPPRLPDSEPPPLPPKNQMNQKDST
NELQSDRNRYSKTSSSTSRESGSRYDYANKFKSHSTDSPPIPLPSRKINRAETSRSSKRS
NDDDDYLTPSVSLSSQNINSTIPQLPPPPPQKNTSKLRGTRKSETDPKNLDAPTPPVSAK
ADSSATAIIPDITLSQLLTLGVDDLAQKLNVQPSKLNTMTLVELTTYLSEFIENSKQSNN
AVPTMAPPPPPIPIRPSLETPVDSPVFKVSFDDAVFEAKFDDNFGELQEQSKQQQHEETN
SFVANFDNFNQAPVSVIPTADRYAVFREIIDQEIQKHQSFDGHQESIESNNSNSLEEIQE
GGSFDFTNDQNQNESPQENQFQQSPIPYQTQCSSKLDNKITEALSGVKDRYAALRELRNI
VLVEDLFDKSPKPPLASISDSNLSDEICDDASSSNQGFALFPTSEIIEDNSMENIPTYNI
SWTNDEVPTETIENIVQEEEQQQQQQSFEDERLSKINNTLNAGSNKDDLEIDEYMNKAIS
ELSLDQRISPNIQNKSPSIKAEDDETLLKPSLTASTECKTSAMVSIENKSSSPIASSLVI
KTESSNEAMNNEKTNSEITEKEESREKTITPVKPIESSESWAVFEDTHIQTKMPEKSNIG
VAKADFESGSSDAHGKMDQSTEKDINILIIIIHLKDILVRKHHLDIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g6594.t1 | CDD | cd01215 | PTB_Dab | 9 | 156 | 3.48734E-83 |
| 9 | g6594.t1 | Coils | Coil | Coil | 148 | 168 | - |
| 8 | g6594.t1 | Coils | Coil | Coil | 207 | 227 | - |
| 7 | g6594.t1 | Gene3D | G3DSA:2.30.29.30 | - | 11 | 164 | 1.7E-36 |
| 16 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 351 | 366 | - |
| 18 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 351 | 372 | - |
| 13 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 545 | 722 | - |
| 12 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 554 | 578 | - |
| 14 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 593 | 624 | - |
| 15 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 651 | 665 | - |
| 17 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 666 | 681 | - |
| 19 | g6594.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1144 | 1167 | - |
| 2 | g6594.t1 | PANTHER | PTHR11232 | PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER | 7 | 257 | 3.7E-147 |
| 4 | g6594.t1 | PANTHER | PTHR11232:SF47 | PROTEIN DISABLED | 7 | 257 | 3.7E-147 |
| 3 | g6594.t1 | PANTHER | PTHR11232 | PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER | 373 | 405 | 3.7E-147 |
| 5 | g6594.t1 | PANTHER | PTHR11232:SF47 | PROTEIN DISABLED | 373 | 405 | 3.7E-147 |
| 1 | g6594.t1 | Pfam | PF00640 | Phosphotyrosine interaction domain (PTB/PID) | 26 | 146 | 1.0E-6 |
| 20 | g6594.t1 | ProSiteProfiles | PS01179 | Phosphotyrosine interaction domain (PID) profile. | 21 | 152 | 30.952 |
| 11 | g6594.t1 | SMART | SM00462 | PTB_9 | 21 | 153 | 6.9E-35 |
| 6 | g6594.t1 | SUPERFAMILY | SSF50729 | PH domain-like | 13 | 151 | 7.65E-35 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0032502 | developmental process | BP |
KEGG
Orthology
- This transcript has been annotated with K12475 (disabled homolog 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
