Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Tyrosine-protein kinase CSK.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g698 g698.t4 isoform g698.t4 5406980 5408279
chr_3 g698 g698.t4 exon g698.t4.exon1 5406980 5408086
chr_3 g698 g698.t4 TTS g698.t4 5407032 5407032
chr_3 g698 g698.t4 cds g698.t4.CDS1 5407823 5408086
chr_3 g698 g698.t4 exon g698.t4.exon2 5408147 5408279
chr_3 g698 g698.t4 cds g698.t4.CDS2 5408147 5408212
chr_3 g698 g698.t4 TSS g698.t4 5408806 5408806

Sequences

>g698.t4 Gene=g698 Length=1240
AAATGTACTTATTTCCGAAGAGTGTGTGGCAAAAGTGGCTGATTTTGGTTTAGCGCGTGA
GGAGTGTATGAACAGCAATGATATAGGAAAACTTCCAATCAAATGGTCAGCACCAGAAGC
TCTTAAAAGTGGCCAATTTTCAAACAAGTCAGACATTTGGAGTTTTGGAATTCTATTATG
GGAAATTTATTCTTTCGGACGTGTTCCTTATCCTCGTATTCCACTTGCAGATGTTACAAA
ACATGTTGAGGCCGGTTATAAAATGGAAGCACCTGAAGGTTGTCCCACAGAAATCTACGA
TATGATGAAAGAATGCTGGGACCTTAATCCAAAAAATCGTCCAACATTTAGAGACCTTGC
GATAAGATTAAAACATTTAAAAACGATAACTACATAAAATTACACTAATTAGATGTGTAT
TATACATAATTATTTAACCTTAGTGTCGAAGTGAGAGTCAACTCTTACTTTTGAAAAAAG
AGAAACGAGATTCAATTCCTTTTTTATTTGTTTTTTGAGTAAGTAAATCTCATAAATGTA
ATTTTTTGATTTTAAAATTAATTTATTTTGTTATTATAAAAAGTGCAATGAAAACTATCT
ATCTAAAATTGAAAAAAAAAATAATTAGTGTGAGAGATCAAAAATGAAATATTAGTGAAC
AAGATATAAAAAATTTTTCTTGTTATTTAGACATTTTTTTGATCAAAAAAGAGAGAATAG
ATGAAAAATTCTTTTTATACTTATGAAACTGGCGATGAATTGAAAATAGAAAAAAAATAT
CGTCAGTAAAACTTACATGGATCACGGTGTCTCCTTAATCAACTACAATATATATTTTTT
ATTAAATCTGATTTTTTGACAAATTTGTTGAGTGTAACAGGACATACATAATATTCATTT
TATCTACATACATAAAAAGTGAAAGGAAAAACAAAAAAAAAAGATTTAACAAACTATCAT
CATCGTCAAAAATTGTTCGTTTTTGTAGGGAAAATTTTATTGCCACACCAAAAAGTCACC
TATACTTGACTATCTACATAATATACTAATCAATAAGTATAGTTCTATTAATCGGTATAA
AAGCGAAAAAAAGAGAAATTGAAAATTGCAAATTCACATTCATTCATTTGTAAAATAAAA
AAGCAAAAACAATAAATTAAAATAAAACTGTAAGTTAATTAACATTTTATTGATGCACTT
CATGTGTCTGTACTTATTATCCAAAAGAAATTTTTTTTAT

>g698.t4 Gene=g698 Length=109
MNSNDIGKLPIKWSAPEALKSGQFSNKSDIWSFGILLWEIYSFGRVPYPRIPLADVTKHV
EAGYKMEAPEGCPTEIYDMMKECWDLNPKNRPTFRDLAIRLKHLKTITT

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g698.t4 Gene3D G3DSA:1.10.510.10 Transferase(Phosphotransferase) domain 1 1 108 0.000
2 g698.t4 PANTHER PTHR24418:SF399 MEGAKARYOCYTE-ASSOCIATED TYROSINE-PROTEIN KINASE 4 103 0.000
3 g698.t4 PANTHER PTHR24418 TYROSINE-PROTEIN KINASE 4 103 0.000
6 g698.t4 PRINTS PR00109 Tyrosine kinase catalytic domain signature 9 19 0.000
5 g698.t4 PRINTS PR00109 Tyrosine kinase catalytic domain signature 28 50 0.000
4 g698.t4 PRINTS PR00109 Tyrosine kinase catalytic domain signature 72 94 0.000
1 g698.t4 Pfam PF07714 Protein tyrosine and serine/threonine kinase 4 98 0.000
10 g698.t4 ProSiteProfiles PS50011 Protein kinase domain profile. 1 106 14.167
8 g698.t4 SMART SM00219 tyrkin_6 1 101 0.000
7 g698.t4 SUPERFAMILY SSF56112 Protein kinase-like (PK-like) 9 103 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004713 protein tyrosine kinase activity MF
GO:0005524 ATP binding MF
GO:0004672 protein kinase activity MF
GO:0006468 protein phosphorylation BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values