General information for g698.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Tyrosine-protein kinase CSK.
Parent gene
- The parent gene g698 is located on chr_3: 5409462..5410346 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g698 | g698.t5 | isoform | g698.t5 | 5407021 | 5408788 |
| chr_3 | g698 | g698.t5 | exon | g698.t5.exon1 | 5407021 | 5408086 |
| chr_3 | g698 | g698.t5 | TTS | g698.t5 | 5407032 | 5407032 |
| chr_3 | g698 | g698.t5 | cds | g698.t5.CDS1 | 5407971 | 5408086 |
| chr_3 | g698 | g698.t5 | exon | g698.t5.exon2 | 5408152 | 5408279 |
| chr_3 | g698 | g698.t5 | cds | g698.t5.CDS2 | 5408152 | 5408279 |
| chr_3 | g698 | g698.t5 | exon | g698.t5.exon3 | 5408495 | 5408560 |
| chr_3 | g698 | g698.t5 | cds | g698.t5.CDS3 | 5408495 | 5408560 |
| chr_3 | g698 | g698.t5 | exon | g698.t5.exon4 | 5408627 | 5408788 |
| chr_3 | g698 | g698.t5 | cds | g698.t5.CDS4 | 5408627 | 5408709 |
| chr_3 | g698 | g698.t5 | TSS | g698.t5 | 5408806 | 5408806 |
Sequences
>g698.t5 Gene=g698 Length=1422
AACATTAGAGCACGAGAATCTTGTGAAATTCATTGGAATAGTCTTCAATAAACAACATCT
TTATCTTGTCACTGAATATATGAGTAAAGGATCATTAGTCGATTATTTAAGATCACGAGG
TCGTCAACACATTACCAGAAAGGATCAAATCAATTTTGCAAGTGACACATGTTCTGGTAT
GGAATATTTAGAAGCAAAGAAAGTTGTGCATCGTGACTTAGCTGCAAGAAATGTACTTAT
TTCCGAAGAGTGTGTGGCAAAAGTGGCTGATTTTGGTTTAGCGCGTGAGGAGTGTATGAA
CAGCAATGATATAGGAAAACTTCCAATCAAATGGTCAGCACCAGAAGCTCTTAAAACAAT
TTTCAAACAAGTCAGACATTTGGAGTTTTGGAATTCTATTATGGGAAATTTATTCTTTCG
GACGTGTTCCTTATCCTCGTATTCCACTTGCAGATGTTACAAAACATGTTGAGGCCGGTT
ATAAAATGGAAGCACCTGAAGGTTGTCCCACAGAAATCTACGATATGATGAAAGAATGCT
GGGACCTTAATCCAAAAAATCGTCCAACATTTAGAGACCTTGCGATAAGATTAAAACATT
TAAAAACGATAACTACATAAAATTACACTAATTAGATGTGTATTATACATAATTATTTAA
CCTTAGTGTCGAAGTGAGAGTCAACTCTTACTTTTGAAAAAAGAGAAACGAGATTCAATT
CCTTTTTTATTTGTTTTTTGAGTAAGTAAATCTCATAAATGTAATTTTTTGATTTTAAAA
TTAATTTATTTTGTTATTATAAAAAGTGCAATGAAAACTATCTATCTAAAATTGAAAAAA
AAAATAATTAGTGTGAGAGATCAAAAATGAAATATTAGTGAACAAGATATAAAAAATTTT
TCTTGTTATTTAGACATTTTTTTGATCAAAAAAGAGAGAATAGATGAAAAATTCTTTTTA
TACTTATGAAACTGGCGATGAATTGAAAATAGAAAAAAAATATCGTCAGTAAAACTTACA
TGGATCACGGTGTCTCCTTAATCAACTACAATATATATTTTTTATTAAATCTGATTTTTT
GACAAATTTGTTGAGTGTAACAGGACATACATAATATTCATTTTATCTACATACATAAAA
AGTGAAAGGAAAAACAAAAAAAAAAGATTTAACAAACTATCATCATCGTCAAAAATTGTT
CGTTTTTGTAGGGAAAATTTTATTGCCACACCAAAAAGTCACCTATACTTGACTATCTAC
ATAATATACTAATCAATAAGTATAGTTCTATTAATCGGTATAAAAGCGAAAAAAAGAGAA
ATTGAAAATTGCAAATTCACATTCATTCATTTGTAAAATAAAAAAGCAAAAACAATAAAT
TAAAATAAAACTGTAAGTTAATTAACATTTTATTGATGCACT
>g698.t5 Gene=g698 Length=130
MSKGSLVDYLRSRGRQHITRKDQINFASDTCSGMEYLEAKKVVHRDLAARNVLISEECVA
KVADFGLAREECMNSNDIGKLPIKWSAPEALKTIFKQVRHLEFWNSIMGNLFFRTCSLSS
YSTCRCYKTC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g698.t5 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 1 | 100 | 4.4E-25 |
| 2 | g698.t5 | PANTHER | PTHR24418:SF399 | MEGAKARYOCYTE-ASSOCIATED TYROSINE-PROTEIN KINASE | 1 | 93 | 7.4E-32 |
| 3 | g698.t5 | PANTHER | PTHR24418 | TYROSINE-PROTEIN KINASE | 1 | 93 | 7.4E-32 |
| 4 | g698.t5 | PRINTS | PR00109 | Tyrosine kinase catalytic domain signature | 36 | 54 | 6.0E-10 |
| 5 | g698.t5 | PRINTS | PR00109 | Tyrosine kinase catalytic domain signature | 81 | 91 | 6.0E-10 |
| 1 | g698.t5 | Pfam | PF07714 | Protein tyrosine and serine/threonine kinase | 1 | 93 | 2.2E-30 |
| 8 | g698.t5 | ProSitePatterns | PS00109 | Tyrosine protein kinases specific active-site signature. | 42 | 54 | - |
| 10 | g698.t5 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 130 | 17.065 |
| 9 | g698.t5 | SMART | SM00219 | tyrkin_6 | 1 | 129 | 6.4E-7 |
| 6 | g698.t5 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 1 | 93 | 1.64E-24 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004713 | protein tyrosine kinase activity | MF |
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
