General information for g7007.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aspartyl/asparaginyl beta-hydroxylase.
Parent gene
- The parent gene g7007 is located on chr_2: 20588347..20592436 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7007 | g7007.t3 | TSS | g7007.t3 | 20583292 | 20583292 |
| chr_2 | g7007 | g7007.t3 | isoform | g7007.t3 | 20583403 | 20589043 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon1 | 20583403 | 20583460 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS1 | 20583403 | 20583460 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon2 | 20583963 | 20584157 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS2 | 20583963 | 20584157 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon3 | 20584215 | 20584669 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS3 | 20584215 | 20584669 |
| chr_2 | g7007 | g7007.t3 | TTS | g7007.t3 | 20584574 | 20584574 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon4 | 20584993 | 20585164 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS4 | 20584993 | 20585164 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon5 | 20585317 | 20585394 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS5 | 20585317 | 20585394 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon6 | 20585764 | 20585892 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS6 | 20585764 | 20585892 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon7 | 20586036 | 20586479 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS7 | 20586036 | 20586479 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon8 | 20586546 | 20586707 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS8 | 20586546 | 20586707 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon9 | 20586862 | 20586935 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS9 | 20586862 | 20586935 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon10 | 20587701 | 20587999 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS10 | 20587701 | 20587999 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon11 | 20588050 | 20588284 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS11 | 20588050 | 20588284 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon12 | 20588345 | 20588918 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS12 | 20588345 | 20588918 |
| chr_2 | g7007 | g7007.t3 | exon | g7007.t3.exon13 | 20588985 | 20589043 |
| chr_2 | g7007 | g7007.t3 | cds | g7007.t3.CDS13 | 20588985 | 20589043 |
Sequences
>g7007.t3 Gene=g7007 Length=2934
ATGTCGGGAGACGTACAAACACGACAAAGGCGAAAGGAGAAGAAAAAACCAAAACGCGAG
GAAGAAATTTCAACAGTTCCTGGAGTTGACACATCAAAATTCAATGAAGCCGAAAAAAAG
ACTGTGCAAATGCACATTCAAGAAAGTGATCATGGTGCAGGCATTTGCGCAAAGATCATT
TTTTTCTCTTTAATGGCAATTTTATTGGGACTTGTGACTCTTATTGTTCTTGAAAATCGC
GGCGGATCTGATGTTGATACACCATTATCAGAATCTCGGTTCTCTGAATATTTAACAGGA
TGGGTAGATGAGAATAGAGAAATAGATGATCATCATGTTGAACCGCATTTTGATATACAT
GATGATGATCCCGACGAAGAGACAACACATGTTTATCAGAAACCGGTTGTACCTGATGAT
GAACCGTTTCCAGAAGAAAGAGATAATTCAAATCCAGATGATGATCATGAAGAATTGAAT
GAAAATTTAAATAATGAATCTGAAAATGATGAAGATGATGTCATATCAGAAAATCAAAAT
GAAATAGATCAACAAGACGAAGAACAAGATGAAGATAACAATGAAAATGAAGTAAATGAT
GAACCATTAAGACAAGAAGAAGAAGAAAATAACGAGAACGAAGCAGCTGATGATGATGAA
AATGAAGTGCCAAATATGTTTGATGACAGTGCACCATTTGATGAGGAGGATGATGATGAT
GAAGACAATTTAAATAGTCAAGAAATTTTTGAAAAAGTAATCGATAATGATGCTGGAGAA
GACTTATTATTGCAAAAATTGGCAGAAGAAAGTGAAAATGCTCAACAGCAGCAATCACAA
GAAAATGATGGAGAAGAAAAAGAAGAAGAATCATCATCACTTATGGTAAAGCTTTTCGTC
GGTCTCCTCTTGGCCATAGTTGCTCATCAAATAATAATTAAGAAGATTTCAGCAACTAAT
AGGATCGATTCAGAATTAAATAGTAATGAAGATTTGCTCAGTAAAAGACGTTTCACTATG
CTCTCAGAATCTGAAGAAAAACTTGTTATTGATGAAAATAATGGTGATAATGAAGAAATA
ATTGAAGTCATGATGATCTCAAGACCCACATTAGTTGGTGAAAATGAAGAATATTCTGAG
GAAGAATTTTCAGAAGAAATCGAAGAGGAAGAGGAAGAGTACAGTGAGGATGAAATAATT
GAAGAATTTACCACTCAAATTCATACACCGCAGACGTTCGAAGATTTCCAAAACATGTAC
AGACCACAACCTGAACGTGTTGAAGAGACAAAAAGAAAAGTAACTTTCAACGAGCCACAA
CCAATAGTTGAAAAAGAAGTTGAAGCCGAAATGGAAGAAAAAATTTTTAAATTACCAACT
ACATCAGCTGTAAAAGAATGTGCAATCGATCAAAAAGATACAAAAGAAAAATTATTGTTA
TCGTCGGATGAATATGAACAAACCGAACATTTAGACATGGAAGAAGAACTTCTTGAAGAT
GAAGAAATTGAGGAAGAAGAAGATCCATCTGGCGAAGATTTATTAGATGAAGAAGAGGAG
CTTGATTATGACGATAGTGAAGAAGACTTGTCAGAAATCGATGACACTGAATTGTTGAAA
CGTCTCGAAGCAAAATATGGTAAAATTGATAACAAGCAATCTGCTGATGATGAGGATGAT
GCTTCCTGGACAAAACTTCCAGAATCAGGTGATAGTGGTGCTCAGAGCTATATGGAGGAG
TTTCTGAAGCAACAAGCACTTGAAGAGAATCCGGAAGTAAAAGATCTCTATGAGAAAGCA
AAGTCATTAGATGCTACAGCAGAAAGAGAAAAGAGCAATAAAATATTATTGGAGGCTATT
GAAAAATATAAAGAACTTATCAATGTTTATGGTGACAAAGTGAATGATACAATATTCAAA
GAAATTGCTGAAAAATGTATCGAGCGAATGAGATTCATGGGAAAACTTAAGCAAACTGTC
GACATTCATTATAAATTAATACATCGATTTGTTGAAAATCCGTCTTACAGGAATCAACTG
GCCGTAACCTACTTATTGGGCAATCGTCTTTCAGCAGCTAAACTTGTACTGCATGAAACG
CTCTCTGAGTGGCGAAACAATGGATTTGCATTAGTTCATTATGGCTATGTATTAAAAAAT
CTCGATCAAGACTACGAAAATGCAATTTTATATTTACGCGAAGGAATAGAAACTAACGAT
CCTGGTACACAAGATGGTAGATTTTATTACAATCTAGGTGATGCTCTCCAAAGACTTGGT
AGACAGGAAGAGGCTTTAGAAGTTTATCGAAAAGGTGCATCAATAGGATTATTTCTATCT
GAATACCAAAGATCTCTCTACAATATAGACAGACTGAAATCAAAGCCATTTTGGACAAAA
GTTGAAACTACTTATAAAGATAATTTAGTAGAAATTCAGAAATATTGGCAAATTATAAGA
GATGAAGGACTGAAATTATTATCAAATGATGGTATATTTATAAATGAACAAGAAAATCTC
AAAGACACCGGAGATTGGAAGCAATTTGAATTATTTGCACGTGGTGCAGCTACGAAATAT
TGTCACATGGCCCCAATCACATGTAAAATAATTAATGGTTTTAAAGCAGCTTCCAGTTGT
AAGAGAGGTCAAGTTAAATTCAGTGTGCTTCATCCAAATACTCATATACATAGTCATTGT
GGCCCAACAAACTGTCGTATAAGAGCGCATTTAGGACTTCAAGTTCCTGAAAAAACGTTC
ATAAGAGTGGCTAATGAAACTCGTTCGTGGAAAGATGGTGAATGGTTGATTTTCGATGAT
TCTTTCGAACATGAAGTTTGGCATAACGGAACGAGCATTCGACTTGTTCTTATTGTTGAT
ATGTATCATCCTGATTTGACTGAAGATGAAAAACGAAGCTTAAGCCCTATTTAA
>g7007.t3 Gene=g7007 Length=977
MSGDVQTRQRRKEKKKPKREEEISTVPGVDTSKFNEAEKKTVQMHIQESDHGAGICAKII
FFSLMAILLGLVTLIVLENRGGSDVDTPLSESRFSEYLTGWVDENREIDDHHVEPHFDIH
DDDPDEETTHVYQKPVVPDDEPFPEERDNSNPDDDHEELNENLNNESENDEDDVISENQN
EIDQQDEEQDEDNNENEVNDEPLRQEEEENNENEAADDDENEVPNMFDDSAPFDEEDDDD
EDNLNSQEIFEKVIDNDAGEDLLLQKLAEESENAQQQQSQENDGEEKEEESSSLMVKLFV
GLLLAIVAHQIIIKKISATNRIDSELNSNEDLLSKRRFTMLSESEEKLVIDENNGDNEEI
IEVMMISRPTLVGENEEYSEEEFSEEIEEEEEEYSEDEIIEEFTTQIHTPQTFEDFQNMY
RPQPERVEETKRKVTFNEPQPIVEKEVEAEMEEKIFKLPTTSAVKECAIDQKDTKEKLLL
SSDEYEQTEHLDMEEELLEDEEIEEEEDPSGEDLLDEEEELDYDDSEEDLSEIDDTELLK
RLEAKYGKIDNKQSADDEDDASWTKLPESGDSGAQSYMEEFLKQQALEENPEVKDLYEKA
KSLDATAEREKSNKILLEAIEKYKELINVYGDKVNDTIFKEIAEKCIERMRFMGKLKQTV
DIHYKLIHRFVENPSYRNQLAVTYLLGNRLSAAKLVLHETLSEWRNNGFALVHYGYVLKN
LDQDYENAILYLREGIETNDPGTQDGRFYYNLGDALQRLGRQEEALEVYRKGASIGLFLS
EYQRSLYNIDRLKSKPFWTKVETTYKDNLVEIQKYWQIIRDEGLKLLSNDGIFINEQENL
KDTGDWKQFELFARGAATKYCHMAPITCKIINGFKAASSCKRGQVKFSVLHPNTHIHSHC
GPTNCRIRAHLGLQVPEKTFIRVANETRSWKDGEWLIFDDSFEHEVWHNGTSIRLVLIVD
MYHPDLTEDEKRSLSPI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g7007.t3 | Coils | Coil | Coil | 153 | 195 | - |
| 14 | g7007.t3 | Coils | Coil | Coil | 267 | 288 | - |
| 13 | g7007.t3 | Coils | Coil | Coil | 380 | 400 | - |
| 12 | g7007.t3 | Coils | Coil | Coil | 593 | 613 | - |
| 9 | g7007.t3 | Gene3D | G3DSA:1.25.40.10 | - | 572 | 777 | 3.3E-13 |
| 10 | g7007.t3 | Gene3D | G3DSA:2.60.120.330 | - | 785 | 976 | 2.3E-64 |
| 27 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 26 | - |
| 29 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 29 | - |
| 25 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 135 | 224 | - |
| 28 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 135 | 158 | - |
| 30 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 159 | 224 | - |
| 24 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 270 | 290 | - |
| 26 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 480 | 536 | - |
| 21 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 488 | 533 | - |
| 22 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 551 | 571 | - |
| 23 | g7007.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 551 | 565 | - |
| 4 | g7007.t3 | PANTHER | PTHR12366 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 1 | 322 | 3.4E-193 |
| 6 | g7007.t3 | PANTHER | PTHR12366:SF29 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 1 | 322 | 3.4E-193 |
| 3 | g7007.t3 | PANTHER | PTHR12366 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 374 | 977 | 3.4E-193 |
| 5 | g7007.t3 | PANTHER | PTHR12366:SF29 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 374 | 977 | 3.4E-193 |
| 2 | g7007.t3 | Pfam | PF13181 | Tetratricopeptide repeat | 747 | 774 | 1.7E-4 |
| 1 | g7007.t3 | Pfam | PF05118 | Aspartyl/Asparaginyl beta-hydroxylase | 814 | 964 | 8.7E-51 |
| 17 | g7007.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 58 | - |
| 18 | g7007.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 59 | 77 | - |
| 15 | g7007.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 78 | 293 | - |
| 19 | g7007.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 294 | 313 | - |
| 16 | g7007.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 314 | 977 | - |
| 31 | g7007.t3 | ProSiteProfiles | PS50293 | TPR repeat region circular profile. | 674 | 779 | 10.002 |
| 7 | g7007.t3 | SUPERFAMILY | SSF48452 | TPR-like | 653 | 776 | 2.13E-11 |
| 8 | g7007.t3 | SUPERFAMILY | SSF51197 | Clavaminate synthase-like | 843 | 965 | 1.51E-16 |
| 20 | g7007.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 54 | 76 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0018193 | peptidyl-amino acid modification | BP |
| GO:0005515 | protein binding | MF |
| GO:0042264 | peptidyl-aspartic acid hydroxylation | BP |
| GO:0004597 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K00476 (aspartate beta-hydroxylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
