Gene loci information

Transcript annotation

  • This transcript has been annotated as Collagen alpha-1(II) chain.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7037 g7037.t1 TTS g7037.t1 20761061 20761061
chr_2 g7037 g7037.t1 isoform g7037.t1 20761106 20766730
chr_2 g7037 g7037.t1 exon g7037.t1.exon1 20761106 20761916
chr_2 g7037 g7037.t1 cds g7037.t1.CDS1 20761106 20761916
chr_2 g7037 g7037.t1 exon g7037.t1.exon2 20761979 20761987
chr_2 g7037 g7037.t1 cds g7037.t1.CDS2 20761979 20761987
chr_2 g7037 g7037.t1 exon g7037.t1.exon3 20762044 20762098
chr_2 g7037 g7037.t1 cds g7037.t1.CDS3 20762044 20762098
chr_2 g7037 g7037.t1 exon g7037.t1.exon4 20762158 20762185
chr_2 g7037 g7037.t1 cds g7037.t1.CDS4 20762158 20762185
chr_2 g7037 g7037.t1 exon g7037.t1.exon5 20762241 20762285
chr_2 g7037 g7037.t1 cds g7037.t1.CDS5 20762241 20762285
chr_2 g7037 g7037.t1 exon g7037.t1.exon6 20762346 20762417
chr_2 g7037 g7037.t1 cds g7037.t1.CDS6 20762346 20762417
chr_2 g7037 g7037.t1 exon g7037.t1.exon7 20762474 20762535
chr_2 g7037 g7037.t1 cds g7037.t1.CDS7 20762474 20762535
chr_2 g7037 g7037.t1 exon g7037.t1.exon8 20762606 20762633
chr_2 g7037 g7037.t1 cds g7037.t1.CDS8 20762606 20762633
chr_2 g7037 g7037.t1 exon g7037.t1.exon9 20762697 20762731
chr_2 g7037 g7037.t1 cds g7037.t1.CDS9 20762697 20762731
chr_2 g7037 g7037.t1 exon g7037.t1.exon10 20762796 20762813
chr_2 g7037 g7037.t1 cds g7037.t1.CDS10 20762796 20762813
chr_2 g7037 g7037.t1 exon g7037.t1.exon11 20762883 20762928
chr_2 g7037 g7037.t1 cds g7037.t1.CDS11 20762883 20762928
chr_2 g7037 g7037.t1 exon g7037.t1.exon12 20762985 20762992
chr_2 g7037 g7037.t1 cds g7037.t1.CDS12 20762985 20762992
chr_2 g7037 g7037.t1 exon g7037.t1.exon13 20763056 20763073
chr_2 g7037 g7037.t1 cds g7037.t1.CDS13 20763056 20763073
chr_2 g7037 g7037.t1 exon g7037.t1.exon14 20763142 20763168
chr_2 g7037 g7037.t1 cds g7037.t1.CDS14 20763142 20763168
chr_2 g7037 g7037.t1 exon g7037.t1.exon15 20763234 20763278
chr_2 g7037 g7037.t1 cds g7037.t1.CDS15 20763234 20763278
chr_2 g7037 g7037.t1 exon g7037.t1.exon16 20763452 20763479
chr_2 g7037 g7037.t1 cds g7037.t1.CDS16 20763452 20763479
chr_2 g7037 g7037.t1 exon g7037.t1.exon17 20763703 20763791
chr_2 g7037 g7037.t1 cds g7037.t1.CDS17 20763703 20763791
chr_2 g7037 g7037.t1 exon g7037.t1.exon18 20763928 20763963
chr_2 g7037 g7037.t1 cds g7037.t1.CDS18 20763928 20763963
chr_2 g7037 g7037.t1 exon g7037.t1.exon19 20764032 20764058
chr_2 g7037 g7037.t1 cds g7037.t1.CDS19 20764032 20764058
chr_2 g7037 g7037.t1 exon g7037.t1.exon20 20764117 20764134
chr_2 g7037 g7037.t1 cds g7037.t1.CDS20 20764117 20764134
chr_2 g7037 g7037.t1 exon g7037.t1.exon21 20764218 20764245
chr_2 g7037 g7037.t1 cds g7037.t1.CDS21 20764218 20764245
chr_2 g7037 g7037.t1 exon g7037.t1.exon22 20764410 20764476
chr_2 g7037 g7037.t1 cds g7037.t1.CDS22 20764410 20764476
chr_2 g7037 g7037.t1 exon g7037.t1.exon23 20764532 20764571
chr_2 g7037 g7037.t1 cds g7037.t1.CDS23 20764532 20764571
chr_2 g7037 g7037.t1 exon g7037.t1.exon24 20764641 20764659
chr_2 g7037 g7037.t1 cds g7037.t1.CDS24 20764641 20764659
chr_2 g7037 g7037.t1 exon g7037.t1.exon25 20764722 20764739
chr_2 g7037 g7037.t1 cds g7037.t1.CDS25 20764722 20764739
chr_2 g7037 g7037.t1 exon g7037.t1.exon26 20765269 20765302
chr_2 g7037 g7037.t1 cds g7037.t1.CDS26 20765269 20765302
chr_2 g7037 g7037.t1 exon g7037.t1.exon27 20765374 20765447
chr_2 g7037 g7037.t1 cds g7037.t1.CDS27 20765374 20765447
chr_2 g7037 g7037.t1 exon g7037.t1.exon28 20765522 20765565
chr_2 g7037 g7037.t1 cds g7037.t1.CDS28 20765522 20765565
chr_2 g7037 g7037.t1 exon g7037.t1.exon29 20765691 20765754
chr_2 g7037 g7037.t1 cds g7037.t1.CDS29 20765691 20765754
chr_2 g7037 g7037.t1 exon g7037.t1.exon30 20765821 20765838
chr_2 g7037 g7037.t1 cds g7037.t1.CDS30 20765821 20765838
chr_2 g7037 g7037.t1 exon g7037.t1.exon31 20765901 20765917
chr_2 g7037 g7037.t1 cds g7037.t1.CDS31 20765901 20765917
chr_2 g7037 g7037.t1 exon g7037.t1.exon32 20766139 20766179
chr_2 g7037 g7037.t1 cds g7037.t1.CDS32 20766139 20766179
chr_2 g7037 g7037.t1 exon g7037.t1.exon33 20766246 20766258
chr_2 g7037 g7037.t1 cds g7037.t1.CDS33 20766246 20766258
chr_2 g7037 g7037.t1 exon g7037.t1.exon34 20766321 20766340
chr_2 g7037 g7037.t1 cds g7037.t1.CDS34 20766321 20766340
chr_2 g7037 g7037.t1 exon g7037.t1.exon35 20766726 20766730
chr_2 g7037 g7037.t1 cds g7037.t1.CDS35 20766726 20766730
chr_2 g7037 g7037.t1 TSS g7037.t1 NA NA

Sequences

>g7037.t1 Gene=g7037 Length=2007
ATGATAGGAGAACCTGGAGAAAAAGGACCACCTGGAGAACCTGGAGCAGTTGGATCTGTT
GGGCCTGTTGGATTGCCTGGTCCTCAGGGCTTACAAGGATTTCCTGGACAACCTGGACCA
ATGGGATTGCCTGGTGTAAAAGGCGAACGCGGACTTATGGGAATTAAAGGAGAACAAGGT
AGTCAAGGTGAAAAAGGAATTACTGGTGAAGTTGGTCCTCCTGGTCCTATTGGATTAACT
GGCCAAAAAGGTGCCAGAGGAGATATTGGAGCAAGAGGAGAAGCTGGAATTATGGGTCCA
CCAGGACGACCAGGCGAAAATGGTGCTCCAGGTCAACCTGGGCAGCCTGGAATTCAAGGA
TTGCCAGGATTGCCGGGAATAAAAGGTGCTGTTGGAGAACAAGGAAGAATTGGAAATCCT
GGTCCAATGGGAAATCAAGGCCCACCCGGAACGCCGGGTGAAAAAGGAGACCCAGGAAGT
GATGGATCTCCAGGGCCGCAAGGAAATCAAGGGCCACAAGGACCTGCTGGAGATAGAGGA
ATGCCAGGTTTGCCGGGACCTGTCGGAGCTATGGGAGCAAAAGGAGCTAGAGGTGCACAA
GGAGAAAAGGGAGAAGCTGGAAAAGATGGAAAAGAAGGTCAACAAGGAGAAAGAGGAGCC
CAAGGAGAGCCTGGCCCAGTTGGCATGCCAGGTCCAGCAGGTGTTCCTGGTATTCAAGGA
CGAGTTGGTGATAAAGGACCAGTGGGAGCTCCTGGAAACACTGGACCCCCAGGTCCTCCG
GGATTGCCAGGTCCAACGGGACCAATCGGACCTGCAGGTGCTGCTGGAGAAAGAGGAACG
AAGGGTGAACAAGGTCAACAAGGGGTTGATGGTCCAATCGGTCCAAGAGGAAAACCAGGT
CCACCTGGAATTGAAGGAATAAAAGGTGAACGTGGAGAAGCAGGCGCCAAAGGAGCAAAA
GGTCACAGAGGATTAGTTGGTTTGCAGGGAATGACTGGAGCACCTGGATTAATTGGAGAA
AAAGGAAATCAAGGAAATATTGGACCTCAAGGACCACCTGGAGAAATGGGTCCTCGAGGT
CCTGCTGGAAGAGATGGAAGCCCAGGTCCACAAGGGTTACCAGGAAATATAGGCCCTAGA
GGTCCACAAGGAGAACCCGGAAAACCAGGATTAAGAGGTGATGTTGGTCCTCCAGGACCA
CCTGGACCACAAGCTGAATCAATTGGTTATGATGCAGCAGCATTAGCAGCTCTTTTAGGT
CATGGTGCGAATAATCAAAAGGGGCCAGATCCTAATGATGATCCTCTCAAACAATTATCA
GATGAAGAAAAACGTGCTATTGTTTTAAAGGCATATGAAAATCTCAAAGTTCGCTTTGAA
AAGTTCAAAAAACCAAATGGAGAGAAACTTTATCCTGCAAAAACTTGTCGTGATTTGGCA
GTTGCTTATCCTGAATATGAAAGCGGAAATTACTGGATTGATCCAAATGATGGTGATGCA
CGCGATGCTATTTTAGTATACTGTGATCTCAAAAAACGTGCAACATGTGTTATACCATCG
CCACTGAAATCTGATGAAATCAGTTATACTGGAAAAGAACCTGAAATTTGGTTGAGTGAG
CTTGAAAAGGGAATGAAGATCAATTATAAAGCAGATAGCAATCAAATGGGATTCTTGCAA
TTACTTTCAACACATGCCACTCAAAATATCACTTTCCATTGTAAAAATACTGTTGCATTC
TTTGATCGTCAAAAGAATAATCATCGAAAAGGTTTGAAACTCATGACTTGGAATGATAAT
GAATTGACACCAAAAGGACCACAAAGATTACGGTATGATGTCTCGGAAGACGGATGTCAA
GAGCGAACTAATTCATGGTCACAAACTGTCATTAGTTATACAACTGAAAAGCCTTTGAGA
CTTCCACTCATGGACATTGCTGTTCGTGATTTTGGTGAATCTGATCAAAAGTTTTGGATT
GAAATTAGTCCTGTTTGCTTCTATTAA

>g7037.t1 Gene=g7037 Length=668
MIGEPGEKGPPGEPGAVGSVGPVGLPGPQGLQGFPGQPGPMGLPGVKGERGLMGIKGEQG
SQGEKGITGEVGPPGPIGLTGQKGARGDIGARGEAGIMGPPGRPGENGAPGQPGQPGIQG
LPGLPGIKGAVGEQGRIGNPGPMGNQGPPGTPGEKGDPGSDGSPGPQGNQGPQGPAGDRG
MPGLPGPVGAMGAKGARGAQGEKGEAGKDGKEGQQGERGAQGEPGPVGMPGPAGVPGIQG
RVGDKGPVGAPGNTGPPGPPGLPGPTGPIGPAGAAGERGTKGEQGQQGVDGPIGPRGKPG
PPGIEGIKGERGEAGAKGAKGHRGLVGLQGMTGAPGLIGEKGNQGNIGPQGPPGEMGPRG
PAGRDGSPGPQGLPGNIGPRGPQGEPGKPGLRGDVGPPGPPGPQAESIGYDAAALAALLG
HGANNQKGPDPNDDPLKQLSDEEKRAIVLKAYENLKVRFEKFKKPNGEKLYPAKTCRDLA
VAYPEYESGNYWIDPNDGDARDAILVYCDLKKRATCVIPSPLKSDEISYTGKEPEIWLSE
LEKGMKINYKADSNQMGFLQLLSTHATQNITFHCKNTVAFFDRQKNNHRKGLKLMTWNDN
ELTPKGPQRLRYDVSEDGCQERTNSWSQTVISYTTEKPLRLPLMDIAVRDFGESDQKFWI
EISPVCFY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
18 g7037.t1 Gene3D G3DSA:2.60.120.1000 - 450 668 1.1E-73
15 g7037.t1 MobiDBLite mobidb-lite consensus disorder prediction 1 36 -
17 g7037.t1 MobiDBLite mobidb-lite consensus disorder prediction 56 113 -
13 g7037.t1 MobiDBLite mobidb-lite consensus disorder prediction 131 306 -
16 g7037.t1 MobiDBLite mobidb-lite consensus disorder prediction 201 216 -
14 g7037.t1 MobiDBLite mobidb-lite consensus disorder prediction 252 267 -
8 g7037.t1 PANTHER PTHR24023:SF569 COLLAGEN ALPHA-1(I) CHAIN 2 201 2.8E-127
11 g7037.t1 PANTHER PTHR24023 COLLAGEN ALPHA 2 201 2.8E-127
7 g7037.t1 PANTHER PTHR24023:SF569 COLLAGEN ALPHA-1(I) CHAIN 129 354 2.8E-127
10 g7037.t1 PANTHER PTHR24023 COLLAGEN ALPHA 129 354 2.8E-127
6 g7037.t1 PANTHER PTHR24023:SF569 COLLAGEN ALPHA-1(I) CHAIN 349 662 2.8E-127
9 g7037.t1 PANTHER PTHR24023 COLLAGEN ALPHA 349 662 2.8E-127
3 g7037.t1 Pfam PF01391 Collagen triple helix repeat (20 copies) 3 58 9.4E-10
1 g7037.t1 Pfam PF01391 Collagen triple helix repeat (20 copies) 255 312 1.0E-6
2 g7037.t1 Pfam PF01391 Collagen triple helix repeat (20 copies) 291 349 2.0E-9
4 g7037.t1 Pfam PF01391 Collagen triple helix repeat (20 copies) 348 404 5.8E-9
5 g7037.t1 Pfam PF01410 Fibrillar collagen C-terminal domain 448 667 4.4E-72
19 g7037.t1 ProSiteProfiles PS51461 Fibrillar collagen C-terminal non-collagenous (NC1) domain profile. 442 668 74.484
12 g7037.t1 SMART SM00038 COLFI_2 445 668 1.7E-76

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005201 extracellular matrix structural constituent MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values