General information for g7052.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Uridine phosphorylase 1.
Parent gene
- The parent gene g7052 is located on chr_2: 20868468..20871007 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7052 | g7052.t1 | TTS | g7052.t1 | 20867324 | 20867324 |
| chr_2 | g7052 | g7052.t1 | isoform | g7052.t1 | 20867448 | 20869739 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon1 | 20867448 | 20867743 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS1 | 20867448 | 20867743 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon2 | 20867803 | 20867944 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS2 | 20867803 | 20867944 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon3 | 20868001 | 20868080 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS3 | 20868001 | 20868080 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon4 | 20868464 | 20868547 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS4 | 20868464 | 20868547 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon5 | 20868646 | 20868691 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS5 | 20868646 | 20868691 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon6 | 20869164 | 20869301 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS6 | 20869164 | 20869301 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon7 | 20869378 | 20869501 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS7 | 20869378 | 20869501 |
| chr_2 | g7052 | g7052.t1 | exon | g7052.t1.exon8 | 20869555 | 20869739 |
| chr_2 | g7052 | g7052.t1 | cds | g7052.t1.CDS8 | 20869555 | 20869739 |
| chr_2 | g7052 | g7052.t1 | TSS | g7052.t1 | NA | NA |
Sequences
>g7052.t1 Gene=g7052 Length=1095
ATGTCAGTCATTCAATCGATCGATATGGATGATATCTATAAAGAGTTGAAAAACAATACA
ATTAAAATTGATGCAAATGGAAATGATATTTCATCTGAAGAAGATTCTGGTTCAGCAACA
AGTGATTCAATTGAAGAGAATGAAAATGAAAGCATAGAGCAATTAAAATTGCGAAGTCTT
ACACGATATAATGATGGAAGTGTTAAATTAAGAAATCCATATATTGAGCAATTGGAATCA
GATTATCTCTATCATTTATCATTGGGAAGTGCTTCACATGACTTGCATGAAATGTTTGGT
GATGTTAAATTTGTCTGTATGGGAGGAACATCTTCTAGAATGAAAGACTTTGCATATTAT
GTGATGAAAGAAATTGGTCATAAACTTCCAGCAGGCACACAATTACAAGACATAAGTGAG
CTTTCTGGCCGTTATTCAATGTATAAGGTTGGCCCGGTTCTTTCGGTGTCTCATGGCATG
GGAACTCCGTCGATTGGGATTTTACTTCATGAGATTATAAAGCTGATGTACCACGCAAAA
TGTAAAGATCCAACTTTCTTCAGAATCGGAACATGTGGTGGGATTGGTATTGATGGAGGT
ACTGTAGTCGTTTCTAATGAAGGAGTTGATGGCTGCTTAAGAAATACCTACGAAGTTGCG
GTTCTTGGAAAAAATATATCTCGCCCAGCAAAACTTGATCAGAAATTAGCTCGTGAACTG
ATGTCACTAGCAGATCTTGAGCGCGATGGATATGAAACAGTTTGCGGCAAAACAATGTGT
GCCAATGACTTCTATGAAGGACAAGGACGTCTGGATGGAGCATTTTGTGATTTTACAGAA
AAAGATAAAATGAATTTTTTGCACAAATGTAAAGACTTTGGTGTTGTAAACATTGAAATG
GAAGCGACAATTTTTGGTGCATTGACATATCATGCAGGAATCAAAGCTGCAATCGTTTGT
GTCGCACTGCTAAACCGTTTAAAAGGAGATCAAGTAAGTACACCAAAAGATATAATGTTG
GAATGGCAAAAACGACCTCAAGTGCTTGTTTCACGATATATCAAAAAGAAATTACGTTTA
AGTCATGGACATTAG
>g7052.t1 Gene=g7052 Length=364
MSVIQSIDMDDIYKELKNNTIKIDANGNDISSEEDSGSATSDSIEENENESIEQLKLRSL
TRYNDGSVKLRNPYIEQLESDYLYHLSLGSASHDLHEMFGDVKFVCMGGTSSRMKDFAYY
VMKEIGHKLPAGTQLQDISELSGRYSMYKVGPVLSVSHGMGTPSIGILLHEIIKLMYHAK
CKDPTFFRIGTCGGIGIDGGTVVVSNEGVDGCLRNTYEVAVLGKNISRPAKLDQKLAREL
MSLADLERDGYETVCGKTMCANDFYEGQGRLDGAFCDFTEKDKMNFLHKCKDFGVVNIEM
EATIFGALTYHAGIKAAIVCVALLNRLKGDQVSTPKDIMLEWQKRPQVLVSRYIKKKLRL
SHGH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g7052.t1 | CDD | cd17763 | UP_hUPP-like | 80 | 356 | 0.0 |
| 7 | g7052.t1 | Gene3D | G3DSA:3.40.50.1580 | - | 56 | 361 | 5.1E-111 |
| 5 | g7052.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 27 | 45 | - |
| 6 | g7052.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 27 | 50 | - |
| 2 | g7052.t1 | PANTHER | PTHR43691:SF3 | FI09636P-RELATED | 61 | 358 | 7.7E-124 |
| 3 | g7052.t1 | PANTHER | PTHR43691 | URIDINE PHOSPHORYLASE | 61 | 358 | 7.7E-124 |
| 1 | g7052.t1 | Pfam | PF01048 | Phosphorylase superfamily | 104 | 354 | 7.4E-26 |
| 4 | g7052.t1 | SUPERFAMILY | SSF53167 | Purine and uridine phosphorylases | 84 | 355 | 3.12E-44 |
| 8 | g7052.t1 | TIGRFAM | TIGR01719 | euk_UDPppase: uridine phosphorylase | 72 | 358 | 2.2E-126 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004850 | uridine phosphorylase activity | MF |
| GO:0009116 | nucleoside metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0005737 | cytoplasm | CC |
| GO:0009166 | nucleotide catabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K00757 (uridine phosphorylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed