Gene loci information

Transcript annotation

  • This transcript has been annotated as Nucleolar GTP-binding protein 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7074 g7074.t1 TTS g7074.t1 21004088 21004088
chr_2 g7074 g7074.t1 isoform g7074.t1 21004180 21006270
chr_2 g7074 g7074.t1 exon g7074.t1.exon1 21004180 21004335
chr_2 g7074 g7074.t1 cds g7074.t1.CDS1 21004180 21004335
chr_2 g7074 g7074.t1 exon g7074.t1.exon2 21004396 21006141
chr_2 g7074 g7074.t1 cds g7074.t1.CDS2 21004396 21006141
chr_2 g7074 g7074.t1 exon g7074.t1.exon3 21006223 21006270
chr_2 g7074 g7074.t1 cds g7074.t1.CDS3 21006223 21006270
chr_2 g7074 g7074.t1 TSS g7074.t1 21006346 21006346

Sequences

>g7074.t1 Gene=g7074 Length=1950
ATGAGTTTGTATAACTTCAAGAAGATAATGGTGGTACCACCAGCAACATCCTTTATCGAT
ATTATGCTGTCGAGAACCCAGCGAAAGACACCAACAGTCGTTCATAAGCACTACAAAATA
TCAAGAATTCGTGCATTCTATATGAGAAAAGTGAAATATACACAACAAAATTTTCATGAT
CGTTTGTCACAAATAATTCAAGATTTTCCAAAACTGGATGATATCCATCCATTTTATGCA
GATTTGATAAATGTTCTCTTTGAAAAAGATCATTATAAACTTGCTCTTGGTCAATTAAAT
ATGGCTCGTCATTTAATTGATAATGTTGCAAAAGAATATGTTCGTTTATTAAAGTATGGT
GATTCACTATATCGTTGTAAACAATTGAAAAAGGCTGCATTAGGTAGAATGGCAACAATC
ATCAAACGTCAGAAAGACAATTTAGCTTATCTTGAAACAGTTCGTCAACATCTTTCGCGT
TTGCCTACAATTGATCCTTATACAAGAACAATAATTTTAACAGGATTTCCTAATGTTGGT
AAATCAAGTTTCATGAATAAAATCACACGTGCGGAAGTCGAAGTTCAACCATATGCTTTC
ACAACAAAAAGTCTTTTTGTTGGACATACAGACTATAAATATTTACGTTGGCAAGTAATT
GATACACCAGGACTTTTGGATCGTTCATTAGAAGATCGAAATGTCATTGAAATGCAAGCT
ATCACTGCACTAGCTCATCTTCGTGCATGTGTTTTATATATAATGGATATTTCAGAAAAC
TGTGGTCATACACTTGAAGAGCAAGTGCATCTTTATGAATCAATTAAACCGCTTTTTGCA
AATAAACCACTTATGATTGTCATCAATAAAGTTGATATTATCAAATTAGACGAATTAGAT
GAGGCACGCCGCAATGTATTGGCAAATATTCTCAATGACGAAAATGTTCCAGTTATTCAA
ATGAGCACAGTTAGTGAAGAAGGTGTGATGGAAGCAAAAACTGAAGCATGTGAGCGCTTG
TTAGGCTTTCGCGTTGATCACAAAATGAAAACCAAGAAAGTTGAAAACATTCTTAATCGT
CTGCATGTCGCAATGCCAGAAAAGCGTGATACAAAAGAAAGACCAGCATTTATTCCTGAG
AGTGTGATGCAAAAACGCGAAATTGATGCTGCAATAAGACAAAAGAGAAAACTAGAGAAG
GATATTGAGGAAGAAGAAGGTGATGATTACATCTTAGATTTAAAGAAACATTATGTGACA
ATACCAGAAGAAGAACGTTACGATATCATACCCGAGTTTTTGGATGGACACAACATTGCA
GATTATATCGATCCAGATATTTTTGAGAAACTTGAAGAGCTTGAACGTGAAGAAGGCATG
CGTTTGGAAAATGGATTTTATGATCCACCGAAGCTCAATATTGATGAAACTCTTCAAGAA
ATTCGTGATATGGCTAGGCAAATTCGCACAAAAAGATTTATCCTTCGAGACAATAAAAAA
TTGGCACCGAAAGCTGATAAGCCTAAGATTCCTCGACACAAATTACCTCACATTCGTGAA
CGTAAAGTTGAAAATTTGAAGAACACTATGGAAGAACTCGGTGTTGATATGAGTGGAAAA
GATGATGCAAACTTTGTTAAGAGTCAAATGAGCTTACGTCGTGGAATTGCACCTGCAATA
GGTGGCAGTATTCAAAAGAAGAAGGACAAAGAATCATCAGCAATTGTCAAATCAACCGGT
CAACCACTCAAACGAAAAGCACCTAAACATGAACTTGGACTCTCAAATGTAATTACAAAA
AAGAAGGCACAAGTAATGGCCAAACACGATATTGCAAAAAAGCTGAAGAAAATGTGTTTG
AAGGGAGAAGCAGATCGTTTTATTGGAGACTTAAAACCCAAACATTTATTCTCTGGAAAG
CGTGGATCAGGCAAAACAGATCGTCGATAA

>g7074.t1 Gene=g7074 Length=649
MSLYNFKKIMVVPPATSFIDIMLSRTQRKTPTVVHKHYKISRIRAFYMRKVKYTQQNFHD
RLSQIIQDFPKLDDIHPFYADLINVLFEKDHYKLALGQLNMARHLIDNVAKEYVRLLKYG
DSLYRCKQLKKAALGRMATIIKRQKDNLAYLETVRQHLSRLPTIDPYTRTIILTGFPNVG
KSSFMNKITRAEVEVQPYAFTTKSLFVGHTDYKYLRWQVIDTPGLLDRSLEDRNVIEMQA
ITALAHLRACVLYIMDISENCGHTLEEQVHLYESIKPLFANKPLMIVINKVDIIKLDELD
EARRNVLANILNDENVPVIQMSTVSEEGVMEAKTEACERLLGFRVDHKMKTKKVENILNR
LHVAMPEKRDTKERPAFIPESVMQKREIDAAIRQKRKLEKDIEEEEGDDYILDLKKHYVT
IPEEERYDIIPEFLDGHNIADYIDPDIFEKLEELEREEGMRLENGFYDPPKLNIDETLQE
IRDMARQIRTKRFILRDNKKLAPKADKPKIPRHKLPHIRERKVENLKNTMEELGVDMSGK
DDANFVKSQMSLRRGIAPAIGGSIQKKKDKESSAIVKSTGQPLKRKAPKHELGLSNVITK
KKAQVMAKHDIAKKLKKMCLKGEADRFIGDLKPKHLFSGKRGSGKTDRR

Protein features from InterProScan

Transcript Database ID Name Start End E.value
14 g7074.t1 CDD cd01897 NOG 169 341 6.58076E-99
12 g7074.t1 Coils Coil Coil 381 408 -
11 g7074.t1 Gene3D G3DSA:1.20.120.1190 - 4 161 6.1E-63
10 g7074.t1 Gene3D G3DSA:3.40.50.300 - 162 363 1.7E-57
4 g7074.t1 PANTHER PTHR45759 NUCLEOLAR GTP-BINDING PROTEIN 1 1 649 1.2E-260
5 g7074.t1 PANTHER PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 1 649 1.2E-260
13 g7074.t1 PIRSF PIRSF038919 NOG1 1 649 2.4E-292
8 g7074.t1 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 171 191 1.7E-9
6 g7074.t1 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 192 210 1.7E-9
7 g7074.t1 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 219 234 1.7E-9
1 g7074.t1 Pfam PF17835 NOG1 N-terminal helical domain 6 165 1.5E-52
3 g7074.t1 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 236 292 7.5E-27
2 g7074.t1 Pfam PF08155 NOGCT (NUC087) domain 396 447 1.8E-20
16 g7074.t1 ProSiteProfiles PS51710 OBG-type guanine nucleotide-binding (G) domain profile. 169 341 40.691
9 g7074.t1 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 48 334 1.59E-41
15 g7074.t1 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 168 331 3.0E-12

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005525 GTP binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values