Gene loci information

Transcript annotation

  • This transcript has been annotated as Nucleolar GTP-binding protein 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7074 g7074.t11 TTS g7074.t11 21004088 21004088
chr_2 g7074 g7074.t11 isoform g7074.t11 21004411 21006098
chr_2 g7074 g7074.t11 exon g7074.t11.exon1 21004411 21006098
chr_2 g7074 g7074.t11 cds g7074.t11.CDS1 21004411 21006048
chr_2 g7074 g7074.t11 TSS g7074.t11 21006346 21006346

Sequences

>g7074.t11 Gene=g7074 Length=1688
CAACAGTCGTTCATAAGCACTACAAAATATCAAGAATTCGTGCATTCTATATGAGAAAAG
TGAAATATACACAACAAAATTTTCATGATCGTTTGTCACAAATAATTCAAGATTTTCCAA
AACTGGATGATATCCATCCATTTTATGCAGATTTGATAAATGTTCTCTTTGAAAAAGATC
ATTATAAACTTGCTCTTGGTCAATTAAATATGGCTCGTCATTTAATTGATAATGTTGCAA
AAGAATATGTTCGTTTATTAAAGTATGGTGATTCACTATATCGTTGTAAACAATTGAAAA
AGGCTGCATTAGGTAGAATGGCAACAATCATCAAACGTCAGAAAGACAATTTAGCTTATC
TTGAAACAGTTCGTCAACATCTTTCGCGTTTGCCTACAATTGATCCTTATACAAGAACAA
TAATTTTAACAGGATTTCCTAATGTTGGTAAATCAAGTTTCATGAATAAAATCACACGTG
CGGAAGTCGAAGTTCAACCATATGCTTTCACAACAAAAAGTCTTTTTGTTGGACATACAG
ACTATAAATATTTACGTTGGCAAGTAATTGATACACCAGGACTTTTGGATCGTTCATTAG
AAGATCGAAATGTCATTGAAATGCAAGCTATCACTGCACTAGCTCATCTTCGTGCATGTG
TTTTATATATAATGGATATTTCAGAAAACTGTGGTCATACACTTGAAGAGCAAGTGCATC
TTTATGAATCAATTAAACCGCTTTTTGCAAATAAACCACTTATGATTGTCATCAATAAAG
TTGATATTATCAAATTAGACGAATTAGATGAGGCACGCCGCAATGTATTGGCAAATATTC
TCAATGACGAAAATGTTCCAGTTATTCAAATGAGCACAGTTAGTGAAGAAGGTGTGATGG
AAGCAAAAACTGAAGCATGTGAGCGCTTGTTAGGCTTTCGCGTTGATCACAAAATGAAAA
CCAAGAAAGTTGAAAACATTCTTAATCGTCTGCATGTCGCAATGCCAGAAAAGCGTGATA
CAAAAGAAAGACCAGCATTTATTCCTGAGAGTGTGATGCAAAAACGCGAAATTGATGCTG
CAATAAGACAAAAGAGAAAACTAGAGAAGGATATTGAGGAAGAAGAAGGTGATGATTACA
TCTTAGATTTAAAGAAACATTATGTGACAATACCAGAAGAAGAACGTTACGATATCATAC
CCGAGTTTTTGGATGGACACAACATTGCAGATTATATCGATCCAGATATTTTTGAGAAAC
TTGAAGAGCTTGAACGTGAAGAAGGCATGCGTTTGGAAAATGGATTTTATGATCCACCGA
AGCTCAATATTGATGAAACTCTTCAAGAAATTCGTGATATGGCTAGGCAAATTCGCACAA
AAAGATTTATCCTTCGAGACAATAAAAAATTGGCACCGAAAGCTGATAAGCCTAAGATTC
CTCGACACAAATTACCTCACATTCGTGAACGTAAAGTTGAAAATTTGAAGAACACTATGG
AAGAACTCGGTGTTGATATGAGTGGAAAAGATGATGCAAACTTTGTTAAGAGTCAAATGA
GCTTACGTCGTGGAATTGCACCTGCAATAGGTGGCAGTATTCAAAAGAAGAAGGACAAAG
AATCATCAGCAATTGTCAAATCAACCGGTCAACCACTCAAACGAAAAGCACCTAAACATG
AACTTGGA

>g7074.t11 Gene=g7074 Length=546
MRKVKYTQQNFHDRLSQIIQDFPKLDDIHPFYADLINVLFEKDHYKLALGQLNMARHLID
NVAKEYVRLLKYGDSLYRCKQLKKAALGRMATIIKRQKDNLAYLETVRQHLSRLPTIDPY
TRTIILTGFPNVGKSSFMNKITRAEVEVQPYAFTTKSLFVGHTDYKYLRWQVIDTPGLLD
RSLEDRNVIEMQAITALAHLRACVLYIMDISENCGHTLEEQVHLYESIKPLFANKPLMIV
INKVDIIKLDELDEARRNVLANILNDENVPVIQMSTVSEEGVMEAKTEACERLLGFRVDH
KMKTKKVENILNRLHVAMPEKRDTKERPAFIPESVMQKREIDAAIRQKRKLEKDIEEEEG
DDYILDLKKHYVTIPEEERYDIIPEFLDGHNIADYIDPDIFEKLEELEREEGMRLENGFY
DPPKLNIDETLQEIRDMARQIRTKRFILRDNKKLAPKADKPKIPRHKLPHIRERKVENLK
NTMEELGVDMSGKDDANFVKSQMSLRRGIAPAIGGSIQKKKDKESSAIVKSTGQPLKRKA
PKHELG

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g7074.t11 CDD cd01897 NOG 122 294 7.99594E-100
12 g7074.t11 Coils Coil Coil 334 361 -
11 g7074.t11 Gene3D G3DSA:1.20.120.1190 - 1 114 4.5E-47
10 g7074.t11 Gene3D G3DSA:3.40.50.300 - 115 317 1.2E-57
14 g7074.t11 MobiDBLite mobidb-lite consensus disorder prediction 510 546 -
4 g7074.t11 PANTHER PTHR45759 NUCLEOLAR GTP-BINDING PROTEIN 1 1 504 2.1E-219
5 g7074.t11 PANTHER PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 1 504 2.1E-219
8 g7074.t11 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 124 144 1.1E-9
7 g7074.t11 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 145 163 1.1E-9
6 g7074.t11 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 172 187 1.1E-9
1 g7074.t11 Pfam PF17835 NOG1 N-terminal helical domain 1 118 4.8E-37
3 g7074.t11 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 189 245 5.9E-27
2 g7074.t11 Pfam PF08155 NOGCT (NUC087) domain 349 400 1.4E-20
16 g7074.t11 ProSiteProfiles PS51710 OBG-type guanine nucleotide-binding (G) domain profile. 122 294 40.691
9 g7074.t11 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 2 287 2.1E-41
15 g7074.t11 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 121 284 2.1E-12

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005525 GTP binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values