General information for g7197.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glutathione S-transferase C-terminal domain-containing protein-like protein.
Parent gene
- The parent gene g7197 is located on chr_2: 22052328..22053499 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7197 | g7197.t1 | TTS | g7197.t1 | 22048930 | 22048930 |
| chr_2 | g7197 | g7197.t1 | isoform | g7197.t1 | 22049269 | 22052741 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon1 | 22049269 | 22049577 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS1 | 22049269 | 22049577 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon2 | 22049639 | 22049790 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS2 | 22049639 | 22049790 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon3 | 22049846 | 22049929 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS3 | 22049846 | 22049929 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon4 | 22050029 | 22050248 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS4 | 22050029 | 22050248 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon5 | 22050471 | 22050815 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS5 | 22050471 | 22050815 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon6 | 22050896 | 22052215 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS6 | 22050896 | 22052215 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon7 | 22052328 | 22052619 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS7 | 22052328 | 22052619 |
| chr_2 | g7197 | g7197.t1 | exon | g7197.t1.exon8 | 22052686 | 22052741 |
| chr_2 | g7197 | g7197.t1 | cds | g7197.t1.CDS8 | 22052686 | 22052741 |
| chr_2 | g7197 | g7197.t1 | TSS | g7197.t1 | 22052855 | 22052855 |
Sequences
>g7197.t1 Gene=g7197 Length=2778
ATGATTGAGCATTTTTCGAAAAAGCGTATGATTTTTGGAATTTTCGTGTTAATTTCTTTG
ACTATTGTTGTGCTACTAATAGAATCTGAGTGGGATCTGATTACACCAAAGCCTCAATCT
TTTGTAGTTGAAAACAATTCAACGTGTTATCTGCGAGAGGAATATCAAATTGTAAAACAT
TGCGAACCGTGCAGTCAGTTTGAGATTAAAGTAGCTCAAACAAATAAGCAAGGAGTTTGT
TTTCATACTCACAACAAAGAAGTACTCAAGTGCCAATCAGGAGAAATTGTCATAAAGTCT
TGTGATAAAGTTGCATTTCTTGAGAGAAAAAATTATTACATTTTTATGATGAATCAATTA
ATTCTGGGCTGTAAAAAACGATCAAATAAATCTTGTGAGTTAACTATCGAGTCATTCATC
ATATTAACGTTATGGAAACTTTTGAAAGGAGAAGAAAAAATTGACATTCAAATATATGAG
GAATATGAAGCAATCAACACAACAACAATAAGCGTGAATTGTAATGAATTAGGCAAAAAT
ATCGAATTTGTTCCAGTAATAGCAGTGAATGAGAAGATTAAATTGCCAATGCTCAAAATC
GACAATGATAATTTTAAAATAATAGGACTCTGTTCAATTCTAAGAGCGATTTGTAGAATT
ATACAAACGTCAAAAGAAGAAGACAAATTAGCGACACAACTTTTGGGTTATAAAGAAAAC
TGTCTCATGGCAACTTCAGAAGTCAGCTTATGGGTTAATTTCTGTGAACGTGAAATGATT
TCTTGTGCTGAAAAATTATTTCAGAAGAAAAATGTCCAAGAAAAAATTGAATTTCCAATA
GAAATACTTAAACTTGAATTAGAGTTCAACAATCCTGTAAGGAGTCATAATGTTTTTCAA
ATAGTTCGTAAAACAAAAAATAATAAGTCTCTTCAAAGTCATTGCGCATTGAATATAGAT
TTGGAGCATAAATATTGTCATGGAAATGAAGCAAATTTATCAGACTGTATTCTCTATGTG
ATTTTCAAATTGATTTTTATGACAGTGGAGGATAATGTTTTTGAAAATAATATACCGCTT
GTTATGTCATGGTTTCATAATATAGAAAATGAAATGAAATATTTGAAGGAGATTATTACT
AATCTATTGATCACGAACATAAAAATGAAAGTACAGTTCAAGAAAGAACTTCCGATTGTT
GAACCTAATGGTAAATACTTTAGTCTCTTCAAACGACAATTACGTGGACAAAAGGCTAAA
ATAAAAGCTCAGAAAAAAATTGTTGACCAAAAAGAAATCGATATGATATTGTCAAAACTA
AAATCAATAGATATAAAGAGCGAGCCCGGCAATGTACATGAACAAAGTTCTTTGAGCGAT
TCATTCATTGAAGAATTGCTTACACGTGGTGAACTTCCTCCCGATAGATTTGAGCGAAAA
AAATTTCAATTAAAAAGTTTAACAGTTGAAGTTTTAAAAATAGCAAAAGATAAAGACGTG
ATTGTCGATTTCTGTTCTGGCACTGGTCATCTTGGTTTATTAATTGCAAAGCTATTGCCA
AATTGCAACATTATTATTTTGGAAAATAAAGAAGAATCAATCAAGAGGGCAAAGCAAAAG
GCTAAAAGTTTAGGCTTGTCGAATGTATCATTCTATCAATGCAATTTGGAGTACTTCTAT
GAGCAATTTACGATTGGTGTAGGATTGCATGCATGCGGCATTGCAACAGACTTATGGATG
AATAAGTGTTATAAAACGGGTGCAAGCTTCGTCTGCAGTCCATGCTGTTATGGAAAGATT
CAAGATTTAGGAAATCTTAATTTACCTCAAAGTAAAATTTTTAAACAAATTCTAAGTACA
CATGAATTTATCAGCATTTCTCATTGTTCGGATCAATCTCATGATGAAAAAAATGTTAAA
CACATAAATTTAGAAAAAGCCCAACAAGGATTTTGGTGTATGGACATAATAGATACAGAT
CGATCTTTAAGAGCTAAAGAATTAGGCTATAAAAAGTACAATGATTCAACGCCAATACCT
ATTCAGACACGTCAATCACGAGTTATGCATTTTGAGGACAAGAATAAAGCCTTCAGGCAA
GTTGTCAACAAGGATCAATTAGCAAAATTAAAAGAGCAACGTCTTCCACCAATTGAACAT
GTTCAAATGATAAATGGTGTTAGAAGAAGAATTTATCAAAATATGCCACTCCGAAAAAAT
CTCGAAATGAAAAATGCTAAGAGAATGAAAATTACTGCTGTTCATTACGATGGGGACACA
ACTAGACTTGAAGGAACCGGTCACCAAAGTTACAAAGGTAACGGAAAAGTGATATTGGAT
AAAAATGAGTACATGCATTGGAAACAAGCGGATTGGGTTCCTGATCATGGCATGGAGAGA
TTTTTCCATATGGATTCTACAGGCACTCTTACTGTAAAAGATCATGGATTGTTTTTGATT
TACGCGCAAGTATATTACAGCGACAATCACGATTTAAATGGCTATGAAATTGTTCATAAC
AATCATGTAAAATATCAGTGCACAACAATGACACATGGTTCTCATGGCGAACCCAAAACA
AACAGTTGCTACACCAGTGGCCTCATTCATTTGAGAAATGGTGATAAAATTCGTTTGCGT
GATGTCGGTAATCATCGATATGTATTGATGCAGCCAAATAAAAGCTTTTTCGGTTTAATT
AAAATCAATCTATTGCCATCAGTTGCATCAGATAGCAGTAGCAGTACAGATATCGAACAA
TACGAATCAATTAAATAA
>g7197.t1 Gene=g7197 Length=925
MIEHFSKKRMIFGIFVLISLTIVVLLIESEWDLITPKPQSFVVENNSTCYLREEYQIVKH
CEPCSQFEIKVAQTNKQGVCFHTHNKEVLKCQSGEIVIKSCDKVAFLERKNYYIFMMNQL
ILGCKKRSNKSCELTIESFIILTLWKLLKGEEKIDIQIYEEYEAINTTTISVNCNELGKN
IEFVPVIAVNEKIKLPMLKIDNDNFKIIGLCSILRAICRIIQTSKEEDKLATQLLGYKEN
CLMATSEVSLWVNFCEREMISCAEKLFQKKNVQEKIEFPIEILKLELEFNNPVRSHNVFQ
IVRKTKNNKSLQSHCALNIDLEHKYCHGNEANLSDCILYVIFKLIFMTVEDNVFENNIPL
VMSWFHNIENEMKYLKEIITNLLITNIKMKVQFKKELPIVEPNGKYFSLFKRQLRGQKAK
IKAQKKIVDQKEIDMILSKLKSIDIKSEPGNVHEQSSLSDSFIEELLTRGELPPDRFERK
KFQLKSLTVEVLKIAKDKDVIVDFCSGTGHLGLLIAKLLPNCNIIILENKEESIKRAKQK
AKSLGLSNVSFYQCNLEYFYEQFTIGVGLHACGIATDLWMNKCYKTGASFVCSPCCYGKI
QDLGNLNLPQSKIFKQILSTHEFISISHCSDQSHDEKNVKHINLEKAQQGFWCMDIIDTD
RSLRAKELGYKKYNDSTPIPIQTRQSRVMHFEDKNKAFRQVVNKDQLAKLKEQRLPPIEH
VQMINGVRRRIYQNMPLRKNLEMKNAKRMKITAVHYDGDTTRLEGTGHQSYKGNGKVILD
KNEYMHWKQADWVPDHGMERFFHMDSTGTLTVKDHGLFLIYAQVYYSDNHDLNGYEIVHN
NHVKYQCTTMTHGSHGEPKTNSCYTSGLIHLRNGDKIRLRDVGNHRYVLMQPNKSFFGLI
KINLLPSVASDSSSSTDIEQYESIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g7197.t1 | CDD | cd02440 | AdoMet_MTases | 501 | 559 | 2.03298E-4 |
| 10 | g7197.t1 | Coils | Coil | Coil | 527 | 547 | - |
| 9 | g7197.t1 | Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 | 470 | 648 | 9.2E-14 |
| 8 | g7197.t1 | Gene3D | G3DSA:2.60.120.40 | - | 769 | 906 | 6.3E-32 |
| 4 | g7197.t1 | PANTHER | PTHR13369:SF0 | GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN | 192 | 671 | 8.0E-93 |
| 5 | g7197.t1 | PANTHER | PTHR13369 | UNCHARACTERIZED | 192 | 671 | 8.0E-93 |
| 3 | g7197.t1 | Pfam | PF05439 | Jumping translocation breakpoint protein (JTB) | 39 | 123 | 1.4E-23 |
| 2 | g7197.t1 | Pfam | PF13847 | Methyltransferase domain | 498 | 629 | 1.0E-11 |
| 1 | g7197.t1 | Pfam | PF00229 | TNF(Tumour Necrosis Factor) family | 807 | 902 | 1.9E-8 |
| 11 | g7197.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 11 | - |
| 13 | g7197.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 31 | - |
| 12 | g7197.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 32 | 925 | - |
| 16 | g7197.t1 | ProSiteProfiles | PS50049 | TNF family profile. | 753 | 902 | 13.74 |
| 7 | g7197.t1 | SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases | 474 | 560 | 3.62E-16 |
| 6 | g7197.t1 | SUPERFAMILY | SSF49842 | TNF-like | 786 | 904 | 4.83E-22 |
| 15 | g7197.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 34 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005164 | tumor necrosis factor receptor binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0006955 | immune response | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
