General information for g7223.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as F-actin-capping protein subunit alpha.
Parent gene
- The parent gene g7223 is located on chr_2: 22196001..22196697 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7223 | g7223.t1 | TTS | g7223.t1 | 22194481 | 22194481 |
| chr_2 | g7223 | g7223.t1 | isoform | g7223.t1 | 22195311 | 22196697 |
| chr_2 | g7223 | g7223.t1 | exon | g7223.t1.exon1 | 22195311 | 22195586 |
| chr_2 | g7223 | g7223.t1 | cds | g7223.t1.CDS1 | 22195311 | 22195586 |
| chr_2 | g7223 | g7223.t1 | exon | g7223.t1.exon2 | 22195640 | 22195992 |
| chr_2 | g7223 | g7223.t1 | cds | g7223.t1.CDS2 | 22195640 | 22195992 |
| chr_2 | g7223 | g7223.t1 | exon | g7223.t1.exon3 | 22196383 | 22196550 |
| chr_2 | g7223 | g7223.t1 | cds | g7223.t1.CDS3 | 22196383 | 22196550 |
| chr_2 | g7223 | g7223.t1 | exon | g7223.t1.exon4 | 22196616 | 22196697 |
| chr_2 | g7223 | g7223.t1 | cds | g7223.t1.CDS4 | 22196616 | 22196697 |
| chr_2 | g7223 | g7223.t1 | TSS | g7223.t1 | 22196755 | 22196755 |
Sequences
>g7223.t1 Gene=g7223 Length=879
ATGTCTAATTTGGAAGAACCTGAGATTTCAGACAATGAAAAGATACGTATAGTAAGCGAC
TTCCTTCTTCACGCACCACCAGGAGAATTTAATGAAGTATTCAACGATGTGAGAGTTTTG
CTTAAAAATGACAATTTGTTAAAAGAAAAGGCAGGTCCTGCGTTTGCACAATATAATAAG
GATCAATTAACGCCAGTTCGTATAGACAGCACTGATTCATATGCATTAATTACAGAATAT
AATGACTTGGGTGCTGGAAGATTTTATGATCCACGCACAAAACAATCATTCAGATATGAT
CATTTAAGAAAGGAAGCGTCTGATTTTCAAAATTTCGAACCAGATCCAATAGCTGAGCCT
TGGAGAGCGGCTCTTGACGTAGAAGCAATTCAATACACTGGTAATCACTATCGTCATGGT
ATGTGTTCAGTTTTTGGTCGTAATGATCCATCAACAAATCAAATTACACTGTCTCTGTGT
ATTGAGGACCATCAATTTCAACCCCAAAATTTTTGGAATGGGAGATGGCGTTCACAATGG
AACTTTACTTTTTCTAATTCTGGAAGTGGTGCGGCTGAGATTAAAGGTGTACTCAAAGTT
CAAGTTCATTACTACGAAGATGGTAATGTTCAATTAGTATCATCGAAAGAATGTCGTGAA
TCTGTAATTGTTACGAATGAAATTCAAACTGCAAAAGAAATCATTAAAGTAGTTGAAGAC
AGTGAACAAGACTATCAAATGGCGATATCAGAGAATTATCAAACAATGTCTGACACGACA
TTCAAAGCTCTTCGCCGCCAATTGCCTGTGACACGCACGAAAATCGATTGGGCCAAAATT
GTATCTTATTCTATTGGTAAGGAGCTAAAAACGCAATAA
>g7223.t1 Gene=g7223 Length=292
MSNLEEPEISDNEKIRIVSDFLLHAPPGEFNEVFNDVRVLLKNDNLLKEKAGPAFAQYNK
DQLTPVRIDSTDSYALITEYNDLGAGRFYDPRTKQSFRYDHLRKEASDFQNFEPDPIAEP
WRAALDVEAIQYTGNHYRHGMCSVFGRNDPSTNQITLSLCIEDHQFQPQNFWNGRWRSQW
NFTFSNSGSGAAEIKGVLKVQVHYYEDGNVQLVSSKECRESVIVTNEIQTAKEIIKVVED
SEQDYQMAISENYQTMSDTTFKALRRQLPVTRTKIDWAKIVSYSIGKELKTQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g7223.t1 | Gene3D | G3DSA:1.20.1290.20 | - | 1 | 113 | 4.3E-44 |
| 10 | g7223.t1 | Gene3D | G3DSA:2.40.160.80 | - | 115 | 264 | 1.5E-54 |
| 2 | g7223.t1 | PANTHER | PTHR10653 | F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA | 3 | 290 | 1.6E-122 |
| 3 | g7223.t1 | PANTHER | PTHR10653:SF5 | F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1 | 3 | 290 | 1.6E-122 |
| 4 | g7223.t1 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 166 | 180 | 1.2E-23 |
| 5 | g7223.t1 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 201 | 214 | 1.2E-23 |
| 6 | g7223.t1 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 258 | 277 | 1.2E-23 |
| 1 | g7223.t1 | Pfam | PF01267 | F-actin capping protein alpha subunit | 18 | 290 | 7.5E-99 |
| 9 | g7223.t1 | ProSitePatterns | PS00748 | F-actin capping protein alpha subunit signature 1. | 202 | 210 | - |
| 8 | g7223.t1 | ProSitePatterns | PS00749 | F-actin capping protein alpha subunit signature 2. | 262 | 272 | - |
| 7 | g7223.t1 | SUPERFAMILY | SSF90096 | Subunits of heterodimeric actin filament capping protein Capz | 9 | 287 | 1.31E-103 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051016 | barbed-end actin filament capping | BP |
| GO:0008290 | F-actin capping protein complex | CC |
KEGG
Orthology
- This transcript has been annotated with K10364 (capping protein (actin filament) muscle Z-line, alpha)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
