General information for g7223.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as F-actin-capping protein subunit alpha.
Parent gene
- The parent gene g7223 is located on chr_2: 22196001..22196697 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7223 | g7223.t4 | TTS | g7223.t4 | 22194481 | 22194481 |
| chr_2 | g7223 | g7223.t4 | isoform | g7223.t4 | 22194503 | 22196697 |
| chr_2 | g7223 | g7223.t4 | exon | g7223.t4.exon1 | 22194503 | 22195586 |
| chr_2 | g7223 | g7223.t4 | cds | g7223.t4.CDS1 | 22195311 | 22195586 |
| chr_2 | g7223 | g7223.t4 | exon | g7223.t4.exon2 | 22195640 | 22195992 |
| chr_2 | g7223 | g7223.t4 | cds | g7223.t4.CDS2 | 22195640 | 22195822 |
| chr_2 | g7223 | g7223.t4 | exon | g7223.t4.exon3 | 22196383 | 22196550 |
| chr_2 | g7223 | g7223.t4 | exon | g7223.t4.exon4 | 22196612 | 22196697 |
| chr_2 | g7223 | g7223.t4 | TSS | g7223.t4 | 22196755 | 22196755 |
Sequences
>g7223.t4 Gene=g7223 Length=1691
ATGTCTAATTTGGAAGAACCTGAGATTTCAGACAATGAAAAGATACGTATAGTAAGCGAC
TTCCTTCTTCACGCACCACCAGGTAAGAGAATTTAATGAAGTATTCAACGATGTGAGAGT
TTTGCTTAAAAATGACAATTTGTTAAAAGAAAAGGCAGGTCCTGCGTTTGCACAATATAA
TAAGGATCAATTAACGCCAGTTCGTATAGACAGCACTGATTCATATGCATTAATTACAGA
ATATAATGACTTGGGTGCTGGAAGATTTTATGATCCACGCACAAAACAATCATTCAGATA
TGATCATTTAAGAAAGGAAGCGTCTGATTTTCAAAATTTCGAACCAGATCCAATAGCTGA
GCCTTGGAGAGCGGCTCTTGACGTAGAAGCAATTCAATACACTGGTAATCACTATCGTCA
TGGTATGTGTTCAGTTTTTGGTCGTAATGATCCATCAACAAATCAAATTACACTGTCTCT
GTGTATTGAGGACCATCAATTTCAACCCCAAAATTTTTGGAATGGGAGATGGCGTTCACA
ATGGAACTTTACTTTTTCTAATTCTGGAAGTGGTGCGGCTGAGATTAAAGGTGTACTCAA
AGTTCAAGTTCATTACTACGAAGATGGTAATGTTCAATTAGTATCATCGAAAGAATGTCG
TGAATCTGTAATTGTTACGAATGAAATTCAAACTGCAAAAGAAATCATTAAAGTAGTTGA
AGACAGTGAACAAGACTATCAAATGGCGATATCAGAGAATTATCAAACAATGTCTGACAC
GACATTCAAAGCTCTTCGCCGCCAATTGCCTGTGACACGCACGAAAATCGATTGGGCCAA
AATTGTATCTTATTCTATTGGTAAGGAGCTAAAAACGCAATAATAATGAATTCCATATGT
GCTCGTCGTCATATGTTTGCTATATGTTTATTATTATTCCTCAATTATTTTTATGATTCT
AAATAATTTTTTCGAACCATACTTTTTCGAATGCTCTTTTTGTTCAAAAAAAGTTTTATC
GAAGAAGTTTATTTTAATTATTTCATACATGTATCTAATCTAATTATAGTAATTGTATTA
TCAGTCTGGGAAATTTTATTCTCTATATTATTATTCACAAATTTTATACAAGAAAAAAGT
TACATTGCCTTTTAAAAAATAATTCTTATACGAGCATACTTTTTTCATATTCTTTGTGTC
AATTCTAGATCAAATGATATTTCTACTACAATTAAATTCGATTTTAATTTCTTGATAATT
ATGAGCTTTTAATTTTTCTAAACCTTTTCCTGGCTCGTTTTCTTAATTCCTAAATACATC
AACCAAACACAATGAAAATTTTGTTTGATTCTTCCTCATCCTTATTTAATTTTGACAAGC
TAAAAAATCATTAAATCAATGAAAAAATAAACTGCGAGCATCTGAGCATATTCTGCATTT
GCAAAAAATCATTAAAATGAAAATAAATTTAGATAAAAAATTCGATAATTGAAGAGCAAA
AGTTGAAAATTAAGTATTAAGCAAACTCTTCTTTTACCAACACTTCGATTACGAACATCA
AAACGAAAAAAGAATTAAAATAAGTGAAACTGTTTTTTAAATGATGAATAAGAACTTGCA
TTATTATAAATAAAAAAAATCTTTGCAAAGACATTAATCACAAAAATAAACTAAAATAAT
GAAAATAAAAT
>g7223.t4 Gene=g7223 Length=152
MCSVFGRNDPSTNQITLSLCIEDHQFQPQNFWNGRWRSQWNFTFSNSGSGAAEIKGVLKV
QVHYYEDGNVQLVSSKECRESVIVTNEIQTAKEIIKVVEDSEQDYQMAISENYQTMSDTT
FKALRRQLPVTRTKIDWAKIVSYSIGKELKTQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g7223.t4 | Gene3D | G3DSA:2.40.160.80 | - | 1 | 124 | 4.7E-47 |
| 2 | g7223.t4 | PANTHER | PTHR10653 | F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA | 1 | 150 | 6.9E-64 |
| 3 | g7223.t4 | PANTHER | PTHR10653:SF2 | F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2 | 1 | 150 | 6.9E-64 |
| 5 | g7223.t4 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 26 | 40 | 2.8E-24 |
| 4 | g7223.t4 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 61 | 74 | 2.8E-24 |
| 6 | g7223.t4 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 118 | 137 | 2.8E-24 |
| 1 | g7223.t4 | Pfam | PF01267 | F-actin capping protein alpha subunit | 2 | 150 | 3.1E-55 |
| 9 | g7223.t4 | ProSitePatterns | PS00748 | F-actin capping protein alpha subunit signature 1. | 62 | 70 | - |
| 8 | g7223.t4 | ProSitePatterns | PS00749 | F-actin capping protein alpha subunit signature 2. | 122 | 132 | - |
| 7 | g7223.t4 | SUPERFAMILY | SSF90096 | Subunits of heterodimeric actin filament capping protein Capz | 11 | 147 | 1.31E-56 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051016 | barbed-end actin filament capping | BP |
| GO:0008290 | F-actin capping protein complex | CC |
KEGG
Orthology
- This transcript has been annotated with K10364 (capping protein (actin filament) muscle Z-line, alpha)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
