General information for g7223.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as F-actin-capping protein subunit alpha.
Parent gene
- The parent gene g7223 is located on chr_2: 22196001..22196697 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7223 | g7223.t5 | TTS | g7223.t5 | 22194938 | 22194938 |
| chr_2 | g7223 | g7223.t5 | isoform | g7223.t5 | 22194967 | 22196697 |
| chr_2 | g7223 | g7223.t5 | exon | g7223.t5.exon1 | 22194967 | 22195586 |
| chr_2 | g7223 | g7223.t5 | cds | g7223.t5.CDS1 | 22195311 | 22195586 |
| chr_2 | g7223 | g7223.t5 | exon | g7223.t5.exon2 | 22195640 | 22195992 |
| chr_2 | g7223 | g7223.t5 | cds | g7223.t5.CDS2 | 22195640 | 22195992 |
| chr_2 | g7223 | g7223.t5 | exon | g7223.t5.exon3 | 22196383 | 22196697 |
| chr_2 | g7223 | g7223.t5 | cds | g7223.t5.CDS3 | 22196383 | 22196569 |
| chr_2 | g7223 | g7223.t5 | TSS | g7223.t5 | 22196755 | 22196755 |
Sequences
>g7223.t5 Gene=g7223 Length=1288
ATGTCTAATTTGGAAGAACCTGAGATTTCAGACAATGAAAAGATACGTATAGTAAGCGAC
TTCCTTCTTCACGCACCACCAGGTAAGTAAAAATGTTTTATTTACACTAAATAAATTAGA
AATTTAATATGAAAAATCATTTTGTAGGAGAATTTAATGAAGTATTCAACGATGTGAGAG
TTTTGCTTAAAAATGACAATTTGTTAAAAGAAAAGGCAGGTCCTGCGTTTGCACAATATA
ATAAGGATCAATTAACGCCAGTTCGTATAGACAGCACTGATTCATATGCATTAATTACAG
AATATAATGACTTGGGTGCTGGAAGATTTTATGATCCACGCACAAAACAATCATTCAGAT
ATGATCATTTAAGAAAGGAAGCGTCTGATTTTCAAAATTTCGAACCAGATCCAATAGCTG
AGCCTTGGAGAGCGGCTCTTGACGTAGAAGCAATTCAATACACTGGTAATCACTATCGTC
ATGGTATGTGTTCAGTTTTTGGTCGTAATGATCCATCAACAAATCAAATTACACTGTCTC
TGTGTATTGAGGACCATCAATTTCAACCCCAAAATTTTTGGAATGGGAGATGGCGTTCAC
AATGGAACTTTACTTTTTCTAATTCTGGAAGTGGTGCGGCTGAGATTAAAGGTGTACTCA
AAGTTCAAGTTCATTACTACGAAGATGGTAATGTTCAATTAGTATCATCGAAAGAATGTC
GTGAATCTGTAATTGTTACGAATGAAATTCAAACTGCAAAAGAAATCATTAAAGTAGTTG
AAGACAGTGAACAAGACTATCAAATGGCGATATCAGAGAATTATCAAACAATGTCTGACA
CGACATTCAAAGCTCTTCGCCGCCAATTGCCTGTGACACGCACGAAAATCGATTGGGCCA
AAATTGTATCTTATTCTATTGGTAAGGAGCTAAAAACGCAATAATAATGAATTCCATATG
TGCTCGTCGTCATATGTTTGCTATATGTTTATTATTATTCCTCAATTATTTTTATGATTC
TAAATAATTTTTTCGAACCATACTTTTTCGAATGCTCTTTTTGTTCAAAAAAAGTTTTAT
CGAAGAAGTTTATTTTAATTATTTCATACATGTATCTAATCTAATTATAGTAATTGTATT
ATCAGTCTGGGAAATTTTATTCTCTATATTATTATTCACAAATTTTATACAAGAAAAAAG
TTACATTGCCTTTTAAAAAATAATTCTTATACGAGCATACTTTTTTCATATTCTTTGTGT
CAATTCTAGATCAAATGATATTTCTACT
>g7223.t5 Gene=g7223 Length=271
MKNHFVGEFNEVFNDVRVLLKNDNLLKEKAGPAFAQYNKDQLTPVRIDSTDSYALITEYN
DLGAGRFYDPRTKQSFRYDHLRKEASDFQNFEPDPIAEPWRAALDVEAIQYTGNHYRHGM
CSVFGRNDPSTNQITLSLCIEDHQFQPQNFWNGRWRSQWNFTFSNSGSGAAEIKGVLKVQ
VHYYEDGNVQLVSSKECRESVIVTNEIQTAKEIIKVVEDSEQDYQMAISENYQTMSDTTF
KALRRQLPVTRTKIDWAKIVSYSIGKELKTQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g7223.t5 | Gene3D | G3DSA:1.20.1290.20 | - | 4 | 92 | 1.4E-32 |
| 10 | g7223.t5 | Gene3D | G3DSA:2.40.160.80 | - | 94 | 243 | 1.2E-54 |
| 2 | g7223.t5 | PANTHER | PTHR10653 | F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA | 7 | 269 | 3.1E-112 |
| 3 | g7223.t5 | PANTHER | PTHR10653:SF5 | F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1 | 7 | 269 | 3.1E-112 |
| 5 | g7223.t5 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 145 | 159 | 1.0E-23 |
| 4 | g7223.t5 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 180 | 193 | 1.0E-23 |
| 6 | g7223.t5 | PRINTS | PR00191 | F-actin capping protein alpha subunit signature | 237 | 256 | 1.0E-23 |
| 1 | g7223.t5 | Pfam | PF01267 | F-actin capping protein alpha subunit | 7 | 269 | 2.2E-93 |
| 9 | g7223.t5 | ProSitePatterns | PS00748 | F-actin capping protein alpha subunit signature 1. | 181 | 189 | - |
| 8 | g7223.t5 | ProSitePatterns | PS00749 | F-actin capping protein alpha subunit signature 2. | 241 | 251 | - |
| 7 | g7223.t5 | SUPERFAMILY | SSF90096 | Subunits of heterodimeric actin filament capping protein Capz | 7 | 266 | 1.7E-94 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051016 | barbed-end actin filament capping | BP |
| GO:0008290 | F-actin capping protein complex | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
