General information for g7274.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Kynurenine formamidase.
Parent gene
- The parent gene g7274 is located on chr_2: 22576057..22576956 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7274 | g7274.t2 | TSS | g7274.t2 | 22575804 | 22575804 |
| chr_2 | g7274 | g7274.t2 | isoform | g7274.t2 | 22575879 | 22576818 |
| chr_2 | g7274 | g7274.t2 | exon | g7274.t2.exon1 | 22575879 | 22575988 |
| chr_2 | g7274 | g7274.t2 | cds | g7274.t2.CDS1 | 22575973 | 22575988 |
| chr_2 | g7274 | g7274.t2 | exon | g7274.t2.exon2 | 22576043 | 22576818 |
| chr_2 | g7274 | g7274.t2 | cds | g7274.t2.CDS2 | 22576043 | 22576818 |
| chr_2 | g7274 | g7274.t2 | TTS | g7274.t2 | 22576951 | 22576951 |
Sequences
>g7274.t2 Gene=g7274 Length=886
ATGACATCACGTGATCTTGAAAAAGAATACGATCCAACTCAATGGTCGCAAAGAATTAAA
GACCCAAAAGAATTACTTGCCAGTCATATCGAATATGGAAACACGGGTCATGTCTGATGC
AAATCGCTATGCTCTCAACTGTCTTTTAAATACACCATACGGTGAATCTTTTCGTCAGAA
GCTTGACATTTATGGAGTTCATTTGCCATTTGAAGCTCCAATTGTAGTCTATGTGCATGG
TGGTTTTTGGCAGCGCAGTAACAAACATACTGCTGCTTATGCAGTTAAACCATTCGTTGA
GAATCAAGCCAAGGTTATTGTTATTGATTTTGACTTGTGTCCTGATGTATCATTAACGGA
GGTCATTAAGCAATTTAAAAAGGCAGTCGAGAGAGTTTTCACTTATGCAGGTGAACACAA
CCCTAAGAGTATTTCGTTTATTGGTCATGATTCTGGAGCTCATTTGATAACGTATTTATT
AAGTGAAGAAATGATTTCTAGTATTGGCACTGATAAATTTAAATTACTTAAGAATATTTA
TTTGATTTCGGGTATTTATGATGTGAGTGACTTACGTCATACTGAACTACATAATCACGG
AAACTTGCTATCAATTACTGATGAGAATGTTGATGAATTAAGTCCAATTAAAGCAAGTTA
TGCTCATTTAGGCAAATATGATATTACTTTTGATGCTTATGTGGGTGGTGATGAATCGCC
AACTTTCCAAAAACAATCACGTGAATTTGTCGCACATTTGAAGATGGAGAAATTGCAAGC
AAATTTCCATAAAATTGATGGATTGGACCATTACGATATTGTGGAAAAATTATCAGAAAT
TAACTATGATGTTACTCAAACAATTATAAGTAATTTAAACAATTAA
>g7274.t2 Gene=g7274 Length=263
METRVMSDANRYALNCLLNTPYGESFRQKLDIYGVHLPFEAPIVVYVHGGFWQRSNKHTA
AYAVKPFVENQAKVIVIDFDLCPDVSLTEVIKQFKKAVERVFTYAGEHNPKSISFIGHDS
GAHLITYLLSEEMISSIGTDKFKLLKNIYLISGIYDVSDLRHTELHNHGNLLSITDENVD
ELSPIKASYAHLGKYDITFDAYVGGDESPTFQKQSREFVAHLKMEKLQANFHKIDGLDHY
DIVEKLSEINYDVTQTIISNLNN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g7274.t2 | Gene3D | G3DSA:3.40.50.1820 | - | 2 | 262 | 0.0e+00 |
| 2 | g7274.t2 | PANTHER | PTHR23024 | ARYLACETAMIDE DEACETYLASE | 26 | 239 | 0.0e+00 |
| 3 | g7274.t2 | PANTHER | PTHR23024:SF554 | KYNURENINE FORMAMIDASE | 26 | 239 | 0.0e+00 |
| 1 | g7274.t2 | Pfam | PF07859 | alpha/beta hydrolase fold | 44 | 164 | 1.6e-05 |
| 4 | g7274.t2 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 16 | 251 | 0.0e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
