General information for g7274.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Kynurenine formamidase.
Parent gene
- The parent gene g7274 is located on chr_2: 22576057..22576956 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7274 | g7274.t3 | TSS | g7274.t3 | 22575804 | 22575804 |
| chr_2 | g7274 | g7274.t3 | isoform | g7274.t3 | 22575879 | 22576818 |
| chr_2 | g7274 | g7274.t3 | exon | g7274.t3.exon1 | 22575879 | 22575975 |
| chr_2 | g7274 | g7274.t3 | cds | g7274.t3.CDS1 | 22575879 | 22575975 |
| chr_2 | g7274 | g7274.t3 | exon | g7274.t3.exon2 | 22576043 | 22576818 |
| chr_2 | g7274 | g7274.t3 | cds | g7274.t3.CDS2 | 22576043 | 22576818 |
| chr_2 | g7274 | g7274.t3 | TTS | g7274.t3 | 22576951 | 22576951 |
Sequences
>g7274.t3 Gene=g7274 Length=873
ATGACATCACGTGATCTTGAAAAAGAATACGATCCAACTCAATGGTCGCAAAGAATTAAA
GACCCAAAAGAATTACTTGCCAGTCATATCGAATATGTGTCTGATGCAAATCGCTATGCT
CTCAACTGTCTTTTAAATACACCATACGGTGAATCTTTTCGTCAGAAGCTTGACATTTAT
GGAGTTCATTTGCCATTTGAAGCTCCAATTGTAGTCTATGTGCATGGTGGTTTTTGGCAG
CGCAGTAACAAACATACTGCTGCTTATGCAGTTAAACCATTCGTTGAGAATCAAGCCAAG
GTTATTGTTATTGATTTTGACTTGTGTCCTGATGTATCATTAACGGAGGTCATTAAGCAA
TTTAAAAAGGCAGTCGAGAGAGTTTTCACTTATGCAGGTGAACACAACCCTAAGAGTATT
TCGTTTATTGGTCATGATTCTGGAGCTCATTTGATAACGTATTTATTAAGTGAAGAAATG
ATTTCTAGTATTGGCACTGATAAATTTAAATTACTTAAGAATATTTATTTGATTTCGGGT
ATTTATGATGTGAGTGACTTACGTCATACTGAACTACATAATCACGGAAACTTGCTATCA
ATTACTGATGAGAATGTTGATGAATTAAGTCCAATTAAAGCAAGTTATGCTCATTTAGGC
AAATATGATATTACTTTTGATGCTTATGTGGGTGGTGATGAATCGCCAACTTTCCAAAAA
CAATCACGTGAATTTGTCGCACATTTGAAGATGGAGAAATTGCAAGCAAATTTCCATAAA
ATTGATGGATTGGACCATTACGATATTGTGGAAAAATTATCAGAAATTAACTATGATGTT
ACTCAAACAATTATAAGTAATTTAAACAATTAA
>g7274.t3 Gene=g7274 Length=290
MTSRDLEKEYDPTQWSQRIKDPKELLASHIEYVSDANRYALNCLLNTPYGESFRQKLDIY
GVHLPFEAPIVVYVHGGFWQRSNKHTAAYAVKPFVENQAKVIVIDFDLCPDVSLTEVIKQ
FKKAVERVFTYAGEHNPKSISFIGHDSGAHLITYLLSEEMISSIGTDKFKLLKNIYLISG
IYDVSDLRHTELHNHGNLLSITDENVDELSPIKASYAHLGKYDITFDAYVGGDESPTFQK
QSREFVAHLKMEKLQANFHKIDGLDHYDIVEKLSEINYDVTQTIISNLNN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g7274.t3 | Gene3D | G3DSA:3.40.50.1820 | - | 1 | 289 | 0.0e+00 |
| 2 | g7274.t3 | PANTHER | PTHR48081:SF8 | AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C | 8 | 273 | 0.0e+00 |
| 3 | g7274.t3 | PANTHER | PTHR48081 | AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C | 8 | 273 | 0.0e+00 |
| 1 | g7274.t3 | Pfam | PF07859 | alpha/beta hydrolase fold | 71 | 190 | 2.1e-05 |
| 4 | g7274.t3 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 38 | 278 | 0.0e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
