Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Kynurenine formamidase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7274 g7274.t4 TSS g7274.t4 22575804 22575804
chr_2 g7274 g7274.t4 isoform g7274.t4 22575879 22576956
chr_2 g7274 g7274.t4 exon g7274.t4.exon1 22575879 22575984
chr_2 g7274 g7274.t4 cds g7274.t4.CDS1 22575879 22575984
chr_2 g7274 g7274.t4 exon g7274.t4.exon2 22576043 22576767
chr_2 g7274 g7274.t4 cds g7274.t4.CDS2 22576043 22576767
chr_2 g7274 g7274.t4 exon g7274.t4.exon3 22576871 22576956
chr_2 g7274 g7274.t4 cds g7274.t4.CDS3 22576871 22576912
chr_2 g7274 g7274.t4 TTS g7274.t4 22576951 22576951

Sequences

>g7274.t4 Gene=g7274 Length=917
ATGACATCACGTGATCTTGAAAAAGAATACGATCCAACTCAATGGTCGCAAAGAATTAAA
GACCCAAAAGAATTACTTGCCAGTCATATCGAATATGGAAACACGGTGTCTGATGCAAAT
CGCTATGCTCTCAACTGTCTTTTAAATACACCATACGGTGAATCTTTTCGTCAGAAGCTT
GACATTTATGGAGTTCATTTGCCATTTGAAGCTCCAATTGTAGTCTATGTGCATGGTGGT
TTTTGGCAGCGCAGTAACAAACATACTGCTGCTTATGCAGTTAAACCATTCGTTGAGAAT
CAAGCCAAGGTTATTGTTATTGATTTTGACTTGTGTCCTGATGTATCATTAACGGAGGTC
ATTAAGCAATTTAAAAAGGCAGTCGAGAGAGTTTTCACTTATGCAGGTGAACACAACCCT
AAGAGTATTTCGTTTATTGGTCATGATTCTGGAGCTCATTTGATAACGTATTTATTAAGT
GAAGAAATGATTTCTAGTATTGGCACTGATAAATTTAAATTACTTAAGAATATTTATTTG
ATTTCGGGTATTTATGATGTGAGTGACTTACGTCATACTGAACTACATAATCACGGAAAC
TTGCTATCAATTACTGATGAGAATGTTGATGAATTAAGTCCAATTAAAGCAAGTTATGCT
CATTTAGGCAAATATGATATTACTTTTGATGCTTATGTGGGTGGTGATGAATCGCCAACT
TTCCAAAAACAATCACGTGAATTTGTCGCACATTTGAAGATGGAGAAATTGCAAGCAAAT
TTCCATAAAATTGATGGATTGGACCATTACGATATTGTGGAAAAATTATCAAACACAATG
CACAATTATTATGAAGAAATTCACGTTTATTAAAAATGTTCAATAAAAAATTTACAGTAT
TATCTTATAAACTAAAA

>g7274.t4 Gene=g7274 Length=290
MTSRDLEKEYDPTQWSQRIKDPKELLASHIEYGNTVSDANRYALNCLLNTPYGESFRQKL
DIYGVHLPFEAPIVVYVHGGFWQRSNKHTAAYAVKPFVENQAKVIVIDFDLCPDVSLTEV
IKQFKKAVERVFTYAGEHNPKSISFIGHDSGAHLITYLLSEEMISSIGTDKFKLLKNIYL
ISGIYDVSDLRHTELHNHGNLLSITDENVDELSPIKASYAHLGKYDITFDAYVGGDESPT
FQKQSREFVAHLKMEKLQANFHKIDGLDHYDIVEKLSNTMHNYYEEIHVY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g7274.t4 Gene3D G3DSA:3.40.50.1820 - 1 288 0.0e+00
2 g7274.t4 PANTHER PTHR48081:SF8 AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C 8 278 0.0e+00
3 g7274.t4 PANTHER PTHR48081 AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C 8 278 0.0e+00
1 g7274.t4 Pfam PF07859 alpha/beta hydrolase fold 74 193 2.1e-05
4 g7274.t4 SUPERFAMILY SSF53474 alpha/beta-Hydrolases 45 276 0.0e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016787 hydrolase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed