General information for g7294.t75
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Catalase.
Parent gene
- The parent gene g7294 is located on chr_2: 22742132..22746850 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7294 | g7294.t75 | TSS | g7294.t75 | 22738599 | 22738599 |
| chr_2 | g7294 | g7294.t75 | isoform | g7294.t75 | 22738616 | 22743186 |
| chr_2 | g7294 | g7294.t75 | exon | g7294.t75.exon1 | 22738616 | 22738668 |
| chr_2 | g7294 | g7294.t75 | exon | g7294.t75.exon2 | 22738732 | 22738820 |
| chr_2 | g7294 | g7294.t75 | cds | g7294.t75.CDS1 | 22738773 | 22738820 |
| chr_2 | g7294 | g7294.t75 | exon | g7294.t75.exon3 | 22741499 | 22741756 |
| chr_2 | g7294 | g7294.t75 | cds | g7294.t75.CDS2 | 22741499 | 22741756 |
| chr_2 | g7294 | g7294.t75 | exon | g7294.t75.exon4 | 22741922 | 22742042 |
| chr_2 | g7294 | g7294.t75 | cds | g7294.t75.CDS3 | 22741922 | 22742042 |
| chr_2 | g7294 | g7294.t75 | exon | g7294.t75.exon5 | 22742132 | 22743186 |
| chr_2 | g7294 | g7294.t75 | cds | g7294.t75.CDS4 | 22742132 | 22743186 |
| chr_2 | g7294 | g7294.t75 | TTS | g7294.t75 | 22743323 | 22743323 |
Sequences
>g7294.t75 Gene=g7294 Length=1576
TTTTCGTACAATTAACAACAAAGAGTGGAATAACATTTTTTCAGCTGATAATTTGTGTGT
GATTTGAAGTGAACAAAAGTGAAAAATAACAAAAATGTCGGCTTCTCAAAATCAACTTAG
TGACTTTAAAAAATCACTTAAGAATGGCCCAGCTGTTGCTACTGTTGGAAATGGTGCACC
AATCGGTGTTAAGACAGCAACACAAACTGTTGGACCACGTGGCCCAGCTCTCTTGCAAGA
TGCAAATTACATCGATGAGATGAGCCACTTTGATCGTGAAAGAGTTCCAGAACGTGTTGT
CCATGCCAAAGGTGCTGGTGCTTTTGGATATTTTGAAGTTACTCATGATATTACAAAATA
CTGTGCTGCAAAAGTCTTTGAAAAAGTTGGAAAACGCACTGTGGTGAAAGTGGATCAGCT
GATACTGTTCGTGATCCTCGTGGTTTTGCTGTTAAATTCTACACTGATGAAGGCATTTGG
GATTTGGTTGGCAATAACACACCGATTTTCTTCATTCGTAAGTGATCCAATCTTGTTCCC
AAGTTTCATTCACACACAAAAGAGAAATCCACAAACACACTTGAAAGACCCCAACATGTT
CTGGGACTTCCTTACTCTTCGTCCAGAATCAACTCATCAAGTTATGTTTTTGTTTGCTGA
TCGTGGCATTCCAGACGGTTTTCGTCATATGAATGGTTATGGTTCACATACATTTAAGAC
TGTTAATGACAAGGGTGAATCATTCTGGGTTAAATTCCATTACAAGACTGCACAAGGTGT
CAAAAATTTGGATATCAAGAAAGCTGAGGAATTGGCAGGAACAAACCCAGATTATGCATT
GCAAGATCTTTTTGATGCAATTGGACGTGGTGATTTCCCACAATGGAACTTCTTCATTCA
AGTTATGACAAATGAGCAAGCAGAGCAATACAAATGGAATCCATTTGATGTCACTAAAGT
TTGGTCACACAAAGATTTCCCATTGATTCCAGTTGGTCGAATGGTTTTGGATAGAAATCC
AAACAATTACTTTGCTGAAGTTGAACAAATTGCATTTTGTCCATCAAATATGGTGCCTGG
TATTGAACCATCACCAGATAAGATGTTGCAAGGTCGTCTTTTCTCATATGTCGACACTCA
TCGTCATCGTTTGGGTGCAAATTATCAAATGTTACCAGTTAACTGTCCATACAGAGTCAG
TATCAAGAACTATCAACGCGATGGTCCAATGTGCTTCGACAGTCAGGGTAATGCACCAAA
TTATTATCCAAACTCATTCGGTGGACCAGAACCAATTAAACGTGCTGTTGATTTGCAACC
ACCATACAAAGTTTCTGGCGAAGTTTTCCGTTATGATAGTGCTGATGAAGACAATTACAG
TCAAGCAACTCTTTTCTGGAATAATGTTTTGGATGAACCTGCAAGAAACCGCATGGTTGA
AAATATTGCTGGACATCTTGTTAATGCTGCAGAATTTATTCAAGAACGCGGAGTCAATAT
GTTCTCAAATGTATCTTCTGATTTCGGTCAAAAATTGAGAGAAGCACTCAATCTTAAGAA
ACAAGGCAAATTGTAA
>g7294.t75 Gene=g7294 Length=493
MSASQNQLSDFKKSLKNGPAVATVGNGAPIGVKTATQTVGPRGPALLQDANYIDEMSHFD
RERVPERVVHAKGAGAFGYFEVTHDITKYCAAKVFEKVGKRTVVKVDQLILFVILVVLLL
NSTLMKAFGIWLAITHRFSSFVSDPILFPSFIHTQKRNPQTHLKDPNMFWDFLTLRPEST
HQVMFLFADRGIPDGFRHMNGYGSHTFKTVNDKGESFWVKFHYKTAQGVKNLDIKKAEEL
AGTNPDYALQDLFDAIGRGDFPQWNFFIQVMTNEQAEQYKWNPFDVTKVWSHKDFPLIPV
GRMVLDRNPNNYFAEVEQIAFCPSNMVPGIEPSPDKMLQGRLFSYVDTHRHRLGANYQML
PVNCPYRVSIKNYQRDGPMCFDSQGNAPNYYPNSFGGPEPIKRAVDLQPPYKVSGEVFRY
DSADEDNYSQATLFWNNVLDEPARNRMVENIAGHLVNAAEFIQERGVNMFSNVSSDFGQK
LREALNLKKQGKL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g7294.t75 | Gene3D | G3DSA:1.10.8.1230 | - | 2 | 63 | 3.5E-22 |
| 13 | g7294.t75 | Gene3D | G3DSA:2.40.180.20 | - | 64 | 106 | 7.1E-16 |
| 15 | g7294.t75 | Gene3D | G3DSA:2.40.180.10 | Catalase HpII | 125 | 490 | 3.6E-165 |
| 5 | g7294.t75 | PANTHER | PTHR11465:SF9 | CATALASE | 20 | 106 | 5.9E-196 |
| 7 | g7294.t75 | PANTHER | PTHR11465 | CATALASE | 20 | 106 | 5.9E-196 |
| 4 | g7294.t75 | PANTHER | PTHR11465:SF9 | CATALASE | 141 | 489 | 5.9E-196 |
| 6 | g7294.t75 | PANTHER | PTHR11465 | CATALASE | 141 | 489 | 5.9E-196 |
| 20 | g7294.t75 | PIRSF | PIRSF038928 | Catalase_clade1-3 | 10 | 108 | 2.8E-30 |
| 19 | g7294.t75 | PIRSF | PIRSF038928 | Catalase_clade1-3 | 129 | 491 | 1.3E-143 |
| 10 | g7294.t75 | PRINTS | PR00067 | Catalase signature | 36 | 59 | 5.8E-38 |
| 8 | g7294.t75 | PRINTS | PR00067 | Catalase signature | 296 | 323 | 5.8E-38 |
| 9 | g7294.t75 | PRINTS | PR00067 | Catalase signature | 328 | 354 | 5.8E-38 |
| 3 | g7294.t75 | Pfam | PF00199 | Catalase | 24 | 104 | 1.2E-30 |
| 2 | g7294.t75 | Pfam | PF00199 | Catalase | 141 | 396 | 2.3E-124 |
| 1 | g7294.t75 | Pfam | PF06628 | Catalase-related immune-responsive | 423 | 485 | 1.5E-18 |
| 16 | g7294.t75 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 108 | - |
| 18 | g7294.t75 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 109 | 134 | - |
| 17 | g7294.t75 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 135 | 493 | - |
| 24 | g7294.t75 | ProSitePatterns | PS00438 | Catalase proximal active site signature. | 59 | 75 | - |
| 23 | g7294.t75 | ProSitePatterns | PS00437 | Catalase proximal heme-ligand signature. | 341 | 349 | - |
| 25 | g7294.t75 | ProSiteProfiles | PS51402 | catalase family profile. | 19 | 491 | 64.69 |
| 22 | g7294.t75 | SMART | SM01060 | Catalase_2 | 23 | 399 | 2.0E-210 |
| 11 | g7294.t75 | SUPERFAMILY | SSF56634 | Heme-dependent catalase-like | 15 | 104 | 1.31E-32 |
| 12 | g7294.t75 | SUPERFAMILY | SSF56634 | Heme-dependent catalase-like | 141 | 487 | 9.55E-140 |
| 21 | g7294.t75 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 109 | 131 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006979 | response to oxidative stress | BP |
| GO:0020037 | heme binding | MF |
| GO:0004096 | catalase activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed