General information for g7315.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aminoacylase-1A.
Parent gene
- The parent gene g7315 is located on chr_2: 22872140..22873482 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7315 | g7315.t1 | TTS | g7315.t1 | 22872081 | 22872081 |
| chr_2 | g7315 | g7315.t1 | isoform | g7315.t1 | 22872140 | 22873482 |
| chr_2 | g7315 | g7315.t1 | exon | g7315.t1.exon1 | 22872140 | 22872347 |
| chr_2 | g7315 | g7315.t1 | cds | g7315.t1.CDS1 | 22872140 | 22872347 |
| chr_2 | g7315 | g7315.t1 | exon | g7315.t1.exon2 | 22872399 | 22873311 |
| chr_2 | g7315 | g7315.t1 | cds | g7315.t1.CDS2 | 22872399 | 22873311 |
| chr_2 | g7315 | g7315.t1 | exon | g7315.t1.exon3 | 22873395 | 22873482 |
| chr_2 | g7315 | g7315.t1 | cds | g7315.t1.CDS3 | 22873395 | 22873482 |
| chr_2 | g7315 | g7315.t1 | TSS | g7315.t1 | 22873516 | 22873516 |
Sequences
>g7315.t1 Gene=g7315 Length=1209
ATGAAAAACCTTTGGGAAAATGATGAAGAAATTAAAATATTTCGAGAATATTTAAGAATC
AAAACTGTCCACCCGAATATAAACTATGCACCGTGCGTTGAATTTTTAAAGCGACAAGCC
GATGAAATTGGCCTTGAATTTCATGTCGTTTATCCATCTTCAGAAATGAAACCGCTTTGC
ATAATTTCCTACCATGGCACCAATTCAAAATTGAAATCAATAATGTTAAGTTCTCATATG
GATGTCGTGCCAGTTGATCGCGAATGTTGGTCATATGATCCATTCGGAGCAGAAATGGAT
GATGATGGAAACATTTTTGCAAGAGGTTCGCAAGATACTAAAGCTATTGGAACTCAATAT
CTCGCTGCTTTACGTTATTTTGTTCGCAATAAAATTCAGTTTAAAAGAACAATTCATGTA
ACTTTTACACCCGAAGAGGAAGTTGGAAGTATTGGTGGAATGAAGGAGTTTATTGAAACA
GAAGCATTTAAAAATCTAAATGTTGGTTTTGCACTTGATGAGGGTGCACCATTATGGAAT
GAATTTTTTACGGCATTTTATGGTGAAAGATCCACTTGGCAGGTTGAATTTATTATAAAA
GGCGAGGCAGGACATGGAAGCATCATGATAGAAGACACAGCAGCAGTAAAATTACAACGA
TTGCTTACAAAACTCACTGAATATCGTCAATCTGAATATGCACGGTTGAGTAGTCGTCTC
GATCTTCAAATGATAGGTCGCATAACGTCATCAAATGTAACAATAATAAATGGTGGTCAC
CAAGCAAATGTTATTCCATCCGAATTTAAAATAATGGTTGATTTTCGTGTGTCAAATGAT
ATTGATCATGAAGAGTTTGTAAAAATGTTTGAAGGTTGGTGTGAGGAAGTAGGTCGTGAC
ATCAGCTATAGATTAGAACTTCGCGAAGATAAAATTGATTTGACAGATATTAGTGAAAAA
AATAAATATTGGACAACATTTAAAAATAGTCTTGATGAACTTGGATTAAAATTAATACCG
ATAATTTGCCCTGCGATGACAGATGCTCGTTTCTTAAGAAAAGTTAAAATTCCTGCGATT
GGTTTTAGTCCGATGAATTTTACTCCGATTTTGGCACACGCTCACAATGAGTTCCTTAAT
GCTGATATTTATCTCAAAGGAATTGAAATTTATAAAAAACTTATCGCTAATTTGGCAAAT
ATGGATTGA
>g7315.t1 Gene=g7315 Length=402
MKNLWENDEEIKIFREYLRIKTVHPNINYAPCVEFLKRQADEIGLEFHVVYPSSEMKPLC
IISYHGTNSKLKSIMLSSHMDVVPVDRECWSYDPFGAEMDDDGNIFARGSQDTKAIGTQY
LAALRYFVRNKIQFKRTIHVTFTPEEEVGSIGGMKEFIETEAFKNLNVGFALDEGAPLWN
EFFTAFYGERSTWQVEFIIKGEAGHGSIMIEDTAAVKLQRLLTKLTEYRQSEYARLSSRL
DLQMIGRITSSNVTIINGGHQANVIPSEFKIMVDFRVSNDIDHEEFVKMFEGWCEEVGRD
ISYRLELREDKIDLTDISEKNKYWTTFKNSLDELGLKLIPIICPAMTDARFLRKVKIPAI
GFSPMNFTPILAHAHNEFLNADIYLKGIEIYKKLIANLANMD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g7315.t1 | Gene3D | G3DSA:3.40.630.10 | Zn peptidases | 3 | 194 | 9.5E-52 |
| 8 | g7315.t1 | Gene3D | G3DSA:3.30.70.360 | - | 195 | 306 | 8.6E-19 |
| 10 | g7315.t1 | Gene3D | G3DSA:3.30.70.1640 | - | 321 | 401 | 1.5E-32 |
| 3 | g7315.t1 | PANTHER | PTHR45892 | AMINOACYLASE-1 | 5 | 401 | 1.1E-139 |
| 4 | g7315.t1 | PANTHER | PTHR45892:SF1 | AMINOACYLASE-1 | 5 | 401 | 1.1E-139 |
| 12 | g7315.t1 | PIRSF | PIRSF036696 | ACY-1 | 1 | 402 | 5.7E-160 |
| 2 | g7315.t1 | Pfam | PF01546 | Peptidase family M20/M25/M40 | 75 | 397 | 1.2E-34 |
| 1 | g7315.t1 | Pfam | PF07687 | Peptidase dimerisation domain | 187 | 299 | 1.4E-13 |
| 7 | g7315.t1 | ProSitePatterns | PS00758 | ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. | 74 | 83 | - |
| 5 | g7315.t1 | SUPERFAMILY | SSF53187 | Zn-dependent exopeptidases | 8 | 400 | 5.74E-56 |
| 6 | g7315.t1 | SUPERFAMILY | SSF55031 | Bacterial exopeptidase dimerisation domain | 193 | 307 | 2.39E-14 |
| 11 | g7315.t1 | TIGRFAM | TIGR01880 | Ac-peptdase-euk: N-acyl-L-amino-acid amidohydrolase | 4 | 400 | 3.4E-146 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0006520 | cellular amino acid metabolic process | BP |
| GO:0004046 | aminoacylase activity | MF |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
- This transcript has been annotated with K01293 (Gly-Xaa carboxypeptidase)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed