General information for g737.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphatidylinositide phosphatase SAC2.
Parent gene
- The parent gene g737 is located on chr_3: 5612786..5613404 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g737 | g737.t1 | TSS | g737.t1 | 5609133 | 5609133 |
| chr_3 | g737 | g737.t1 | isoform | g737.t1 | 5609222 | 5612890 |
| chr_3 | g737 | g737.t1 | exon | g737.t1.exon1 | 5609222 | 5609318 |
| chr_3 | g737 | g737.t1 | cds | g737.t1.CDS1 | 5609222 | 5609318 |
| chr_3 | g737 | g737.t1 | exon | g737.t1.exon2 | 5609417 | 5610343 |
| chr_3 | g737 | g737.t1 | cds | g737.t1.CDS2 | 5609417 | 5610343 |
| chr_3 | g737 | g737.t1 | exon | g737.t1.exon3 | 5610447 | 5611038 |
| chr_3 | g737 | g737.t1 | cds | g737.t1.CDS3 | 5610447 | 5611038 |
| chr_3 | g737 | g737.t1 | exon | g737.t1.exon4 | 5611105 | 5611332 |
| chr_3 | g737 | g737.t1 | cds | g737.t1.CDS4 | 5611105 | 5611332 |
| chr_3 | g737 | g737.t1 | exon | g737.t1.exon5 | 5611397 | 5612723 |
| chr_3 | g737 | g737.t1 | cds | g737.t1.CDS5 | 5611397 | 5612723 |
| chr_3 | g737 | g737.t1 | exon | g737.t1.exon6 | 5612786 | 5612890 |
| chr_3 | g737 | g737.t1 | cds | g737.t1.CDS6 | 5612786 | 5612890 |
| chr_3 | g737 | g737.t1 | TTS | g737.t1 | 5613636 | 5613636 |
Sequences
>g737.t1 Gene=g737 Length=3276
ATGGAAGTGTTTGAGACTGAAAAGAACTACATCTTCATAAAAGATGGAAAATCTCTTTGG
TGGAACAGAACAACTGGTGAATTTCAAGAGAAATCTGCTTTCGATTTCGCTGAAGTGTTT
GACATTGAGTGTATAGGAATTACATATGGAATAATTGGTGAAGTTAAATATACTGGTGTT
TATGATTCACATTTAATTATTATAAAAGATGTACAAGCAGTTGGTTCTTTAGATCAAAAG
AATCTCGTTTATAAAATTAAAAGTGTTTGTATTCTAAGTCAAGATTATCCAACATGCCAA
CTAATTCCATGTCCAAAACATGCAACAACAATGCCACCAAGTCGACCACCTACATCTTCT
CTATCTTCTACTGTAGGAGTAACAACAAGCCCACAATCTAAGACGAAAATTTTTGATGCC
TCTTCTAATTTGATGAATAAAACATGGGGTGTAATGAAAAGCGCTGGAAGCACAATCAAA
AGTACTACACAGCAGGCAGCCAGTATTGCAACAACACAAGTTAAATCTAAAGTTGGTATT
AAAGAATCGTATAAGAAACTTGAAAAAAGAATCAGTGAAGAAATACACAAAATTTTCGAT
GACACAGACTCGTTTTATTATAGTCCCGATAGTGACATTACAAATAATTTACAACGCAAG
GAGTCAATGACATTCGATGACAGATTTTTTTGGAACAAACACATGTTAACATCAATTTTG
AAATTAGAAGATAAGATATGGACAGTTCCAATCATTCAAGGGTTCGTACAAATAGAGCAA
TGTGTTATTGAAAACGAATGTTTTACGCTAGCGCTTGTTTCACGGCGCTCACGATTTCGT
GCTGGTACACGTTATAAACGAAGAGGTATTGATGAAGACGGTAATGTTGCAAATTATGTT
GAAACTGAGCAAATACTTTCATTACGACAACATCAAATTTCATTTACTGGTATAAGAGGT
TCAGTACCCTTATTTTGGTCACAACCTGGATACAAATATCGACCAGCACCAATTATTAAT
AGAGATGATGAGGAAACACAAAAAGCTTTTGCAAAACATTTCGATAAAGAGCTTGAAATT
TACAATAACATTTGCATCGTGAGCCTCGTTGAGCAAACTGGAAAAGAGAAAATTATTGGT
GATAAATATGCGGAACACATTATTCGTTATAATAGCGAGAAACTTATGTATGTGACTTTT
GATTTTCATGAATATTGTCGAGGAATGCGATTTGAAAATGTATCAGCATTGATTGAAGCC
TTAGCAACAGAACTTCATGATTTTGGATTTCATTGGCGTGATAATAATGGTCCAATAAAA
AATCAAAGTGGAATATTTCGAGTCAATTGTATGGATTGTTTGGATAGAACTAATGTAGTT
CAAACTGCAATGGCTAAAGCAATTTTGGAGTCTCAATTGGTGAAACTTGGTCTTGCTCCA
CCATATTCTCAACTTCCTATTGAATTGAAATCAATTTTCATGACCTTATGGGCTAATAAT
GGCGATGTTATTTCAAGACAATATGCTGGAACGAATGCACTTAAAGGCGATTACACAAGA
ACGGGTGAAAGAAAAATCTCTGGCATGGTCAAAGATGGAATGAATTCAGCTAATCGTTAT
TATCTACAACACTTCGTCGATACATTTCGACAAGGCGTTATCGATCTTTTGCTTGGGAAT
CTTGAAGACATCAGTGAAATTTCATTTGATGATCCATTTGAACAAATTACACAAATTGCA
CAAACCGCTTTAATACCCGAATCGCGTGCACCTAAAAATTTCTATTATCATGGTGCTATG
GGAAACGACTTAAAATTCATAGAAGATTCTGTCCTTTTTGCTAGTTACTATTTGGCGCGT
TTTAAAGATACATATAGACAGGCAACAATTGATTTGATGATGGGAAATAATGTTTCAGCA
GAATCTCTGAGTGCTCTTGGTGGACAACAAATCACTGATGAAACAGATGCTGCTGAAAAT
GCAGAACATGCACGATTACTCGTTGAAGATTGCAAGAGAATGTTATTAGGTGGTGAATTA
GTCATAGGTTCATGGGGATTAATTGATGCCGATCCATCTACTGGAGATATAAATGAAACT
GAAGTTGATACCATATTATTGCTTACCAGTACAGAATTTTATGTTGCTGACTATGACAGT
CAATTAGACAAAATTGTTAAATTTGAAAACGTATCGCTTAATAACATCACTTTGATAGAA
TTTGGAATGTTTCAACAACAACAGATTTTTAAAGGACCATCAACTGCACATTTATGCATT
CGTATAAATTATACGATTGATAATGTTGATGGATATTTTCACATGTTCCGTTCACCAAAT
ATTAGATTCTTCAATAATACTGCAGTTGTTATAGAAAAACATGAAGAACTTTTAGAATCA
ATGACAGCAATAGTGGAATTTTTCAGAATTGCTTTACAAAATCTTGGTAGAAATGATGTT
CAATTTCATTGTGGTGGTGCTTTGCAAAGGAGGAAGAGTAGAAATATGCTTCAGCCTCCA
GGCATTCCTCGTAATTTGAGTGAGTCACAACTTGTTCAAATAGGATCGAAAGCACTGAGT
AATGTTGCTGGACAATTTTCAAAATTAGGTCAAACTTTTAATTCTTCAAAAAGTAAAAAT
AAGCAAAATGCAAATCCACCAATTGCTTATAATGCATCAAATGCTGCTAGTTCTTTCTAT
GTTGGTCGCGAAGCTAAAGAAGAAGATTCTGACGACGATAATGATTGCTCGATTTATGAA
CCAGATGCAATTGAGACCGAACAAAACCCAATATTTAACGAAAATGCATTCCTTCCTAGT
GTCGGTATTGTCATGTCAAATCCATCAAATGATGATGAAGAATCACCTGAAATGCTTCAA
ACTAAGAATCCCAGTAAAAATCAATCAGATATGCAAGCAATTTCAATATGCAGTGTAACT
GATCACATTCATGTTCCTTCTGCTATGCAGCCGCTTTCTCCAATGATGAGCCCAATGAAG
CATGCACCTGAAATTATAATTGATAGTGCTATACCGAGAGGAAAAAATGAAATGACATTG
AACCTAAGTGGATCTCAAAGTGAAAATGCAATAAAACAATTAAAAACTTTAACAAGTCCT
TTAAGCATGTTTGCAAAAGGTGTTCAAAGTAGCTTGGGCTTGTCTTCAAAGTCACAAACA
CAATTAAGTGAAATTCTTACAAGTGACATCAACACAAAGAAGTTAGAAGAGAAATTTGCT
GAAAGTAAATGCAAATCAAAATTGATAGCATTATAA
>g737.t1 Gene=g737 Length=1091
MEVFETEKNYIFIKDGKSLWWNRTTGEFQEKSAFDFAEVFDIECIGITYGIIGEVKYTGV
YDSHLIIIKDVQAVGSLDQKNLVYKIKSVCILSQDYPTCQLIPCPKHATTMPPSRPPTSS
LSSTVGVTTSPQSKTKIFDASSNLMNKTWGVMKSAGSTIKSTTQQAASIATTQVKSKVGI
KESYKKLEKRISEEIHKIFDDTDSFYYSPDSDITNNLQRKESMTFDDRFFWNKHMLTSIL
KLEDKIWTVPIIQGFVQIEQCVIENECFTLALVSRRSRFRAGTRYKRRGIDEDGNVANYV
ETEQILSLRQHQISFTGIRGSVPLFWSQPGYKYRPAPIINRDDEETQKAFAKHFDKELEI
YNNICIVSLVEQTGKEKIIGDKYAEHIIRYNSEKLMYVTFDFHEYCRGMRFENVSALIEA
LATELHDFGFHWRDNNGPIKNQSGIFRVNCMDCLDRTNVVQTAMAKAILESQLVKLGLAP
PYSQLPIELKSIFMTLWANNGDVISRQYAGTNALKGDYTRTGERKISGMVKDGMNSANRY
YLQHFVDTFRQGVIDLLLGNLEDISEISFDDPFEQITQIAQTALIPESRAPKNFYYHGAM
GNDLKFIEDSVLFASYYLARFKDTYRQATIDLMMGNNVSAESLSALGGQQITDETDAAEN
AEHARLLVEDCKRMLLGGELVIGSWGLIDADPSTGDINETEVDTILLLTSTEFYVADYDS
QLDKIVKFENVSLNNITLIEFGMFQQQQIFKGPSTAHLCIRINYTIDNVDGYFHMFRSPN
IRFFNNTAVVIEKHEELLESMTAIVEFFRIALQNLGRNDVQFHCGGALQRRKSRNMLQPP
GIPRNLSESQLVQIGSKALSNVAGQFSKLGQTFNSSKSKNKQNANPPIAYNASNAASSFY
VGREAKEEDSDDDNDCSIYEPDAIETEQNPIFNENAFLPSVGIVMSNPSNDDEESPEMLQ
TKNPSKNQSDMQAISICSVTDHIHVPSAMQPLSPMMSPMKHAPEIIIDSAIPRGKNEMTL
NLSGSQSENAIKQLKTLTSPLSMFAKGVQSSLGLSSKSQTQLSEILTSDINTKKLEEKFA
ESKCKSKLIAL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g737.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 949 | 969 | - |
| 3 | g737.t1 | PANTHER | PTHR45662:SF8 | PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC2 | 10 | 566 | 7.0E-290 |
| 5 | g737.t1 | PANTHER | PTHR45662 | PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 | 10 | 566 | 7.0E-290 |
| 4 | g737.t1 | PANTHER | PTHR45662:SF8 | PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC2 | 615 | 937 | 7.0E-290 |
| 6 | g737.t1 | PANTHER | PTHR45662 | PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 | 615 | 937 | 7.0E-290 |
| 2 | g737.t1 | Pfam | PF02383 | SacI homology domain | 49 | 407 | 7.6E-86 |
| 1 | g737.t1 | Pfam | PF12456 | Inositol phosphatase | 657 | 765 | 2.1E-22 |
| 8 | g737.t1 | ProSiteProfiles | PS50275 | Sac phosphatase domain profile. | 196 | 510 | 76.439 |
| 9 | g737.t1 | ProSiteProfiles | PS51791 | hSac2 domain profile. | 657 | 813 | 10.7 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0042578 | phosphoric ester hydrolase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K21798 (phosphatidylinositol 4-phosphatase [EC:3.1.3.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
