Gene loci information

Transcript annotation

  • This transcript has been annotated as Major facilitator superfamily domain-containing protein 8.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7372 g7372.t1 TTS g7372.t1 23431653 23431653
chr_2 g7372 g7372.t1 isoform g7372.t1 23431836 23434028
chr_2 g7372 g7372.t1 exon g7372.t1.exon1 23431836 23432058
chr_2 g7372 g7372.t1 cds g7372.t1.CDS1 23431836 23432058
chr_2 g7372 g7372.t1 exon g7372.t1.exon2 23432119 23432190
chr_2 g7372 g7372.t1 cds g7372.t1.CDS2 23432119 23432190
chr_2 g7372 g7372.t1 exon g7372.t1.exon3 23432251 23432344
chr_2 g7372 g7372.t1 cds g7372.t1.CDS3 23432251 23432344
chr_2 g7372 g7372.t1 exon g7372.t1.exon4 23432425 23433105
chr_2 g7372 g7372.t1 cds g7372.t1.CDS4 23432425 23433105
chr_2 g7372 g7372.t1 exon g7372.t1.exon5 23433178 23433445
chr_2 g7372 g7372.t1 cds g7372.t1.CDS5 23433178 23433445
chr_2 g7372 g7372.t1 exon g7372.t1.exon6 23433840 23434028
chr_2 g7372 g7372.t1 cds g7372.t1.CDS6 23433840 23434028
chr_2 g7372 g7372.t1 TSS g7372.t1 23434811 23434811

Sequences

>g7372.t1 Gene=g7372 Length=1527
ATGGAAAGTTCTAGTGAAAATAAAAAGAAGGAATCTATAGCTAATGGAAATGGCACAATT
AAGCCTCTTGAAACTTCAGAGGAAGAAAAAGAGAGATATAAATCATTGTACATAATTTAT
TTCACACTTTTCCTTCAATCTTTGGGTCTTGCGGTTTGCATGACTGGAATTTGGCCTTAT
GTCAGTAAACTTGATCCAGGAACAACAAAGGAATTTTATTCGTTAATAGTAGCAGCTAAT
CCACTAGGTCAATTCATATTCTCTCCTTTGATTGGACTTTGGCAGAATAAGTCTGCATCA
ATTCGTTGGCCAATTATAACATCATTAATTATCTTCATAATTTCAAACGCTTTCTATTCA
TCACTTGATATGCTAGTTGGCTATGGAGTCAAATATTGGATGCTAATAATTCGATTTTTT
ACTGGCGTTGCTTCGGCAAATATTGCTGTCGGTAGAGGCTATATATCAGCTGCAACAAAA
GTAGAAGAGAGAACACATGTTCTATCAATGGCGTCGCTCTCACAAGTCGGCGGTTTCATT
GCTGGTCCTTTATTGCAAGCTGTTTTTACTGCAATTGGTGAAGGATATGTTTTGTCTTCT
GGTTATCATATTTCCATGTACACTGTGCCCGGTTTGATTAACACAATTCTCGGTGCTATA
AATATATTTTTCTTTCTCCCTCACATTTTTGTTGATCATAATATCGCGGTTCGTGAACAA
ATGGCATTACAAGGAAAAGAATCAGCCAAAGAAACATATAAGTCTGTTAAAATTGATTAC
TTAGTGACTTGTGCATTGATCTTCTCTTACTTTATTGTTTGTGTTAATCTTGTTTTACTC
GAGAGTCTCGGAACGCCTTTGACAATGGATCAATTTGGATTCTCTCGAAAAGATACGCTT
AAGTGGAACGGAATCCTTGTGGGAATTGGGGCTTTTGTGTCGTGTGTAATATTTTGTTTG
TTGCCTCGTCTTTCAAAGATCTTAAAAGAAATTGATATACTCATATGGGGAGGTATGTTC
ATAGCGGTTATTGGAAAAATTATCTATATTCCATATCGTGGTGACCCGCCACCAATTGCT
GATGAAAACTTCAATTCAACAATATTTTTAAATAATGACAATTCAACTGAAATATTGGGT
TGTCCAGTGAAGACTCAGAGTTGGTGTGCAACTACTTCACATGCCCTTGGTATACCTGAA
TTTGTTATTGGATACTTTTTTGGTGTTATAGGTTATCCCGTTGGTGTCACTTTAATTCAA
ACGCTTTTTTCGAAAATTCTCGGAGCAAGACCACAAGGCACATGGATGGGAATAATGTTA
GCAGCAGGTAGTATGAGTCGAATTGTGGGTCCTATTGTTATCGTTGCATCTTACACTGAA
TTTGGATTGGGATACACATTTGCATGGATAACAATCTTTATGTGCATTCCTATGATTCTT
CTCTATTCTTTACGTAATCGTCTCATTACTGATACTCCAAAGGCAGACAACATTAATATG
ACTGATGTAAAGTCTCAAACTGCGTAG

>g7372.t1 Gene=g7372 Length=508
MESSSENKKKESIANGNGTIKPLETSEEEKERYKSLYIIYFTLFLQSLGLAVCMTGIWPY
VSKLDPGTTKEFYSLIVAANPLGQFIFSPLIGLWQNKSASIRWPIITSLIIFIISNAFYS
SLDMLVGYGVKYWMLIIRFFTGVASANIAVGRGYISAATKVEERTHVLSMASLSQVGGFI
AGPLLQAVFTAIGEGYVLSSGYHISMYTVPGLINTILGAINIFFFLPHIFVDHNIAVREQ
MALQGKESAKETYKSVKIDYLVTCALIFSYFIVCVNLVLLESLGTPLTMDQFGFSRKDTL
KWNGILVGIGAFVSCVIFCLLPRLSKILKEIDILIWGGMFIAVIGKIIYIPYRGDPPPIA
DENFNSTIFLNNDNSTEILGCPVKTQSWCATTSHALGIPEFVIGYFFGVIGYPVGVTLIQ
TLFSKILGARPQGTWMGIMLAAGSMSRIVGPIVIVASYTEFGLGYTFAWITIFMCIPMIL
LYSLRNRLITDTPKADNINMTDVKSQTA

Protein features from InterProScan

Transcript Database ID Name Start End E.value
42 g7372.t1 CDD cd17326 MFS_MFSD8 36 489 8.67479E-93
2 g7372.t1 PANTHER PTHR23510:SF3 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8 24 489 2.8E-121
3 g7372.t1 PANTHER PTHR23510 INNER MEMBRANE TRANSPORT PROTEIN YAJR 24 489 2.8E-121
1 g7372.t1 Pfam PF07690 Major Facilitator Superfamily 40 349 6.0E-24
21 g7372.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 1 36 -
37 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 37 60 -
24 g7372.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 61 71 -
31 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 72 94 -
19 g7372.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 95 100 -
41 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 101 120 -
28 g7372.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 121 131 -
38 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 132 155 -
18 g7372.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 156 166 -
36 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 167 192 -
29 g7372.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 193 211 -
33 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 212 231 -
23 g7372.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 232 259 -
39 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 260 280 -
27 g7372.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 281 299 -
35 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 300 321 -
22 g7372.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 322 332 -
40 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 333 352 -
26 g7372.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 353 401 -
30 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 402 423 -
20 g7372.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 424 434 -
34 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 435 458 -
25 g7372.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 459 463 -
32 g7372.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 464 484 -
17 g7372.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 485 508 -
16 g7372.t1 SUPERFAMILY SSF103473 MFS general substrate transporter 28 488 2.49E-33
4 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 40 62 -
5 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 72 94 -
15 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 101 119 -
9 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 134 156 -
13 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 176 198 -
8 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 208 230 -
10 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 260 282 -
11 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 302 321 -
12 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 333 352 -
14 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 401 423 -
7 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 435 457 -
6 g7372.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 462 484 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0055085 transmembrane transport BP
GO:0022857 transmembrane transporter activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values