Gene loci information

Transcript annotation

  • This transcript has been annotated as Sodium/hydrogen exchanger 7.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7512 g7512.t7 isoform g7512.t7 24142892 24145835
chr_2 g7512 g7512.t7 exon g7512.t7.exon1 24142892 24143763
chr_2 g7512 g7512.t7 cds g7512.t7.CDS1 24143278 24143763
chr_2 g7512 g7512.t7 exon g7512.t7.exon2 24143823 24143994
chr_2 g7512 g7512.t7 cds g7512.t7.CDS2 24143823 24143994
chr_2 g7512 g7512.t7 exon g7512.t7.exon3 24144053 24144363
chr_2 g7512 g7512.t7 cds g7512.t7.CDS3 24144053 24144363
chr_2 g7512 g7512.t7 exon g7512.t7.exon4 24144518 24144550
chr_2 g7512 g7512.t7 cds g7512.t7.CDS4 24144518 24144550
chr_2 g7512 g7512.t7 exon g7512.t7.exon5 24144756 24144874
chr_2 g7512 g7512.t7 cds g7512.t7.CDS5 24144756 24144874
chr_2 g7512 g7512.t7 exon g7512.t7.exon6 24144932 24145139
chr_2 g7512 g7512.t7 cds g7512.t7.CDS6 24144932 24145139
chr_2 g7512 g7512.t7 exon g7512.t7.exon7 24145797 24145835
chr_2 g7512 g7512.t7 cds g7512.t7.CDS7 24145797 24145835
chr_2 g7512 g7512.t7 TTS g7512.t7 24146047 24146047
chr_2 g7512 g7512.t7 TSS g7512.t7 NA NA

Sequences

>g7512.t7 Gene=g7512 Length=1754
TCATTGTAGGAGCGATAATTCGTTTTGCTGGAAACAGTTCACCAACAACACATTTACGTG
TTGAAGCTGATAAGTCAACAAAATACAATGACACTCTACCACCTGATGCTTTGTGGTTAA
AATTTCCAGGAAATTTAAATATTTCTGGCCCAACACAAAATCAAACTTATGCATACTCAT
TTCGTGGTCAACTTTATGGCAATTTAAATGAAATCGATTTGAAAGCAACTTTCGATCCAG
AAATTTTTTTCAACATTATTCTACCGCCAATTATTTTCTATGCTGGTTATAGCTTGAAGC
GAAAATATTTCTTTAGAAATTTGGGAACAATTCTAACTTTTGCTATAATTGGAACAACTC
TTTCGGCATTGCTGATTGGTGCACTTATGTATTGCTTTGTACAACTGATTTCAATTCGCG
AAAGCTTTACCTTCTTAGACACACTTTATTTTGGTGCACTCATAAGTCCAACCGATCCGC
TCACAATTTTGGCAATATTTAGTGAGAAAAATGTTGATGTTAATCTATACGCTCTGGTTT
TTGGTGAGAGCGTGCTCAATGATGCCGTTGCAATAGTTTTGAGTGGAGCTATTCAAAATT
ATGGCGAGCATTATTCAAAAACAGGAGATTTTGAGACACATGCGTTTATACATGCTCTTA
AAGACTTCTTTTTTATATTTTTCTTCTCACTGGTTGTCGGCACTTCAATGGGCTGTCTCA
CATCGCTTATGACAAAGTTTACAAAAATTAGAGAATTCCCGCTACTTGAATCTGCATTAT
TTGTGCTCATGTCGTACAGTACTTTCCTCATTGCTGAGGTTTTTGAATTGACTGGAGTTG
TAGCTGTGCTATTTTGTGGAATTTGTCAAGCACATTATACATTCAATAATTTATCAGAAG
AGTCAAGGACAAGAACAAAGCAGTTGTTTGAGCTTTTGAACTTTTTAGCAGAAAATTTTA
TCTTTTCATATATTGGTGTGTCGATGTTTTCATTTCCTCGACATCATTTTGATGCTCTTT
TCATCATTGGTGGATTTTTATGTGCAATGATTGGTAGAGCAGTAAATGTTTATCCTTTAG
CATGGGTAATTAACTTGGGACGAAAGCCTAAAATGCCTTGGAACTTTCAACATATGTTGT
TCTTTGCTGGTCTTCGTGGTGCAATGTCTTTTGCTCTTGCGATTCGCAACACTGTCTCAG
AAGCACGTCAAACTATGCTCACATGTACATCATTAATTGTAATTGTGTCAGTACTTTTTC
AAGGTGGTGCAGCAAATTTCGTCCTACAATTTCTAAAAATTCCAATTGGAGTTGAAGATG
AAACAGAGCAGCTAACTTATCAGTCTGTCAAAAGTGTGTACTGCTCAATGGATAACAATA
CTGTTGCGGATTTGGAAAGTCCTGATCCCCATTCACCAAGTGGTAGTGATCAACCTCAAA
CAAGTACATCAACTAGAAAGAATGAAAAAGCATTGTTGGCTAGAATATGGGGAAATTTCG
ATTCAAGATATATGAAGCCATTTTTAACAAATTCACGTCCAACACTGTTAGAAACATTAC
CAGAATTTTTGACACCACTTGCACGAGTGCTTACTACAACCGAACAATTAAATCAAAGTG
GTCGTACTAGGAAACTCGATTCAGATTCAGATTTATGCATAGATGAAACAAATGGCGGTG
GTGGTGGAAGTACGAGAAGAAATTCAATAAGTCGAGTTCTACCACGAAGTCCTCATTCAT
CAGCTATTATTTGA

>g7512.t7 Gene=g7512 Length=455
MYCFVQLISIRESFTFLDTLYFGALISPTDPLTILAIFSEKNVDVNLYALVFGESVLNDA
VAIVLSGAIQNYGEHYSKTGDFETHAFIHALKDFFFIFFFSLVVGTSMGCLTSLMTKFTK
IREFPLLESALFVLMSYSTFLIAEVFELTGVVAVLFCGICQAHYTFNNLSEESRTRTKQL
FELLNFLAENFIFSYIGVSMFSFPRHHFDALFIIGGFLCAMIGRAVNVYPLAWVINLGRK
PKMPWNFQHMLFFAGLRGAMSFALAIRNTVSEARQTMLTCTSLIVIVSVLFQGGAANFVL
QFLKIPIGVEDETEQLTYQSVKSVYCSMDNNTVADLESPDPHSPSGSDQPQTSTSTRKNE
KALLARIWGNFDSRYMKPFLTNSRPTLLETLPEFLTPLARVLTTTEQLNQSGRTRKLDSD
SDLCIDETNGGGGGSTRRNSISRVLPRSPHSSAII

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g7512.t7 MobiDBLite mobidb-lite consensus disorder prediction 336 359 -
11 g7512.t7 MobiDBLite mobidb-lite consensus disorder prediction 408 455 -
10 g7512.t7 MobiDBLite mobidb-lite consensus disorder prediction 432 455 -
2 g7512.t7 PANTHER PTHR10110 SODIUM/HYDROGEN EXCHANGER 10 427 1.8E-139
3 g7512.t7 PANTHER PTHR10110:SF94 SODIUM/HYDROGEN EXCHANGER 6 10 427 1.8E-139
1 g7512.t7 Pfam PF00999 Sodium/hydrogen exchanger family 14 300 5.4E-55
20 g7512.t7 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 19 -
22 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 20 38 -
15 g7512.t7 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 39 44 -
24 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 45 69 -
19 g7512.t7 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 70 93 -
23 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 94 116 -
12 g7512.t7 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 117 136 -
25 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 137 164 -
16 g7512.t7 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 165 183 -
27 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 184 203 -
14 g7512.t7 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 204 209 -
28 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 210 235 -
18 g7512.t7 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 236 246 -
21 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 247 266 -
13 g7512.t7 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 267 277 -
26 g7512.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 278 300 -
17 g7512.t7 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 301 455 -
6 g7512.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 94 116 -
5 g7512.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 138 160 -
4 g7512.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 181 203 -
8 g7512.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 213 235 -
7 g7512.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 277 299 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0055085 transmembrane transport BP
GO:0016021 integral component of membrane CC
GO:0015299 solute:proton antiporter activity MF
GO:0006812 cation transport BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values