Gene loci information

Transcript annotation

  • This transcript has been annotated as Proteasome subunit beta type-4.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7764 g7764.t1 TSS g7764.t1 25865022 25865022
chr_2 g7764 g7764.t1 isoform g7764.t1 25865112 25866081
chr_2 g7764 g7764.t1 exon g7764.t1.exon1 25865112 25865245
chr_2 g7764 g7764.t1 cds g7764.t1.CDS1 25865112 25865245
chr_2 g7764 g7764.t1 exon g7764.t1.exon2 25865436 25866081
chr_2 g7764 g7764.t1 cds g7764.t1.CDS2 25865436 25866081
chr_2 g7764 g7764.t1 TTS g7764.t1 25866145 25866145

Sequences

>g7764.t1 Gene=g7764 Length=780
ATGATGTCGAATAATGGAGTTAATTTCGCACCGTTTTGGCATAATGGACCAGCACCAGGT
AGTTTTTATAACTTCCCTCAAAATAATATCAAATCAAATTCGGCAATTGATGAATATGGA
TTTCAAAGAAATGGAGGCCCAATAACAACTGGAACTTCAATAGTCGGTGTTAAATACGAT
AAAGGTGTTATAATTGCTGGAGATAAGCTTGTAAGCTACGGAAATTTAGCTCGCTACCAT
AATGTTGATCGTGTATTTAAGATAAATGAAAACATAATTTTGGGGATGAGTGGCGATTAC
GCGGATTTTCAATTTATTAAACAGTACATTGATGAAATAATTCTCTCTGATTTTTCGGCT
GATGATAGAATTGTATTAAAACCAAAAGATTTATATACATGGTTAACAAGAGTTTTGTAC
AATCGTCGTTCACGTTTTAATCCTTTGTGGCTTGATATGGTTGTCGGAGGAATGCAAGGT
GAAGAACCCTTTTTGGGCCATATTAACATTCGTGGAAGATCATATACAAACGACGTCATT
TCAACCGGCTATGGTACTCATCTTGCTCTTCCTTTACTTCGCGAATATTCGGAAAAAGGA
CCATTAAATGAAGAGACTGCTCAGCAGCTTATTCAAAAATCGATGGAAGTATTGTTCTAC
CGTGATTGTCGTGGTTATCCAAAATATTCTCAAGCAAACATCAATGCAAATGGTGTAACT
GTAAGTGATCATGAAGTTAAACAAAATTGGGATTTGGCTCTGAGCATTAAGGGATATTAA

>g7764.t1 Gene=g7764 Length=259
MMSNNGVNFAPFWHNGPAPGSFYNFPQNNIKSNSAIDEYGFQRNGGPITTGTSIVGVKYD
KGVIIAGDKLVSYGNLARYHNVDRVFKINENIILGMSGDYADFQFIKQYIDEIILSDFSA
DDRIVLKPKDLYTWLTRVLYNRRSRFNPLWLDMVVGGMQGEEPFLGHINIRGRSYTNDVI
STGYGTHLALPLLREYSEKGPLNEETAQQLIQKSMEVLFYRDCRGYPKYSQANINANGVT
VSDHEVKQNWDLALSIKGY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g7764.t1 CDD cd03760 proteasome_beta_type_4 50 243 2.51808E-102
5 g7764.t1 Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate 45 259 1.4E-54
2 g7764.t1 PANTHER PTHR11599:SF5 PROTEASOME SUBUNIT BETA TYPE-4 35 246 6.0E-60
3 g7764.t1 PANTHER PTHR11599 PROTEASOME SUBUNIT ALPHA/BETA 35 246 6.0E-60
6 g7764.t1 PIRSF PIRSF001213 MCP 7 259 1.5E-91
1 g7764.t1 Pfam PF00227 Proteasome subunit 49 225 1.7E-28
8 g7764.t1 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 55 102 -
9 g7764.t1 ProSiteProfiles PS51476 Proteasome beta-type subunit profile. 51 234 32.067
4 g7764.t1 SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) 47 251 4.48E-48

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0051603 proteolysis involved in cellular protein catabolic process BP
GO:0004298 threonine-type endopeptidase activity MF
GO:0005839 proteasome core complex CC

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values