General information for g7773.t67
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Myotubularin-related protein 2.
Parent gene
- The parent gene g7773 is located on chr_2: 25897307..25898302 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7773 | g7773.t67 | isoform | g7773.t67 | 25895913 | 25897307 |
| chr_2 | g7773 | g7773.t67 | exon | g7773.t67.exon1 | 25895913 | 25897004 |
| chr_2 | g7773 | g7773.t67 | cds | g7773.t67.CDS1 | 25896343 | 25897004 |
| chr_2 | g7773 | g7773.t67 | exon | g7773.t67.exon2 | 25897061 | 25897307 |
| chr_2 | g7773 | g7773.t67 | cds | g7773.t67.CDS2 | 25897061 | 25897241 |
| chr_2 | g7773 | g7773.t67 | TSS | g7773.t67 | NA | NA |
| chr_2 | g7773 | g7773.t67 | TTS | g7773.t67 | NA | NA |
Sequences
>g7773.t67 Gene=g7773 Length=1339
TATGAATCAGAGAATGACTATCAAAATGTTGAATTGATTTTCTTAGATATTCACAATATT
CATGTAATGCGTGAAAGTTTAAGAAAACTCAAAGAAATTTGCTTTCCTGCAACTGATGAT
CAAAAATGGCTTTCATCTGTTGATAATACAATGTGGCTTAAGCATATCAAATGTGTACTT
GCTGGTGCCATTCGAATTGTTGATCGTATTGAAAATACTAAAAATTCTGTAGTGGTTCAT
TGTTCTGATGGATGGGATAGAACTGCACAATTGACTGCTTTAGCAATGATTATGTTGGAT
CCATATTATAGGACAATAAAAGGTTTTGAAGTGCTAATAGAAAAAGAATGGCTTAGTTTT
GGACATAAATTCCAACAACGTATTGGACATGGTGACATCAATCATTCAGATGCAGATCGT
TCACCAGTTTTTGTTCAATTTATTGACTGTGTGTGGCAAATTACAAGACAACTGCCAAAC
TCTTTTGAGTTTAATGAAAATTTCCTCATTACAATTCTTGATCATCTATATTCATGTCGA
TTCGGTACATTTTTATGTAACACAGAACGTGAGCGGGTAAATGAGGTGAAGAAATATACA
GTTTCATTATGGTCATACATAAATGCATCACTTGAACTCTACAGAAATCCACTTTATGGT
GGATTCGGTAATTCTCCGACTCTACAAACAGTTTTAAAACCTGTTGCAAGTATGAGACAT
ATAAGATTATGGAAAGGTTATTATTGTCGTTGGAATCCAACAATGAAAACGCAAGAACCA
ATTTATCAGCGAACAAGAGAACTCCTTGCATTGCAAGATCAATTAAGAAAACAAATTGAC
GAAATTCTCGAATGTCGCACTGATGGCAATCGTACGACTTTATCAAGGCTAGCCTCTCCG
TTACATTAAAGTTTTATTATTATTCGTTATAATGCATTTATCACAGTATCGACAAACTTT
ATTTAAAAAATTAGATAGAATTCATTTATTGTCAAATTTACACATATTTAAGCACCATTC
ATTCATTAATATTTTATCAAATCAATCAACTTTTTTGACTTTACATTATTTTACATGTAG
AGATTTATTGAATGAATTTGTTCCTTGCAAGTCTTAAACTTAATCCTGTTGTATCTGGAA
GTATAGAAGTGAACGCAATTGCTCCGCCAATAATCATAATTACACCAAATATACTAATAA
AATGCATAATAGAAATATTTTTAAAATAGAAATAAGAGACAATTAAGAGAATTTGTATGG
AACATTCAATAATATTGGTCATTGCAATAAAGAAAGGTTTAACTCGCGTATTAACGCTAT
CGACTAAGAAAATATCAGA
>g7773.t67 Gene=g7773 Length=280
MRESLRKLKEICFPATDDQKWLSSVDNTMWLKHIKCVLAGAIRIVDRIENTKNSVVVHCS
DGWDRTAQLTALAMIMLDPYYRTIKGFEVLIEKEWLSFGHKFQQRIGHGDINHSDADRSP
VFVQFIDCVWQITRQLPNSFEFNENFLITILDHLYSCRFGTFLCNTERERVNEVKKYTVS
LWSYINASLELYRNPLYGGFGNSPTLQTVLKPVASMRHIRLWKGYYCRWNPTMKTQEPIY
QRTRELLALQDQLRKQIDEILECRTDGNRTTLSRLASPLH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7773.t67 | Gene3D | G3DSA:3.90.190.10 | Protein tyrosine phosphatase superfamily | 12 | 144 | 9.9E-6 |
| 2 | g7773.t67 | PANTHER | PTHR10807:SF42 | MYOTUBULARIN-RELATED PROTEIN 2 | 1 | 278 | 2.1E-132 |
| 3 | g7773.t67 | PANTHER | PTHR10807 | MYOTUBULARIN-RELATED | 1 | 278 | 2.1E-132 |
| 1 | g7773.t67 | Pfam | PF06602 | Myotubularin-like phosphatase domain | 1 | 170 | 6.9E-86 |
| 6 | g7773.t67 | ProSitePatterns | PS00383 | Tyrosine specific protein phosphatases active site. | 57 | 67 | - |
| 8 | g7773.t67 | ProSiteProfiles | PS51339 | Myotubularin phosphatase domain. | 1 | 226 | 82.057 |
| 5 | g7773.t67 | SMART | SM00404 | ptp_7 | 16 | 155 | 1.3E-4 |
| 4 | g7773.t67 | SUPERFAMILY | SSF52799 | (Phosphotyrosine protein) phosphatases II | 1 | 231 | 6.29E-93 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016311 | dephosphorylation | BP |
| GO:0004725 | protein tyrosine phosphatase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
