Gene loci information

Transcript annotation

  • This transcript has been annotated as Myotubularin-related protein 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7773 g7773.t68 isoform g7773.t68 25895913 25898302
chr_2 g7773 g7773.t68 exon g7773.t68.exon1 25895913 25896305
chr_2 g7773 g7773.t68 cds g7773.t68.CDS1 25896286 25896305
chr_2 g7773 g7773.t68 exon g7773.t68.exon2 25896381 25897004
chr_2 g7773 g7773.t68 cds g7773.t68.CDS2 25896381 25897004
chr_2 g7773 g7773.t68 exon g7773.t68.exon3 25897061 25897664
chr_2 g7773 g7773.t68 cds g7773.t68.CDS3 25897061 25897664
chr_2 g7773 g7773.t68 exon g7773.t68.exon4 25897723 25898178
chr_2 g7773 g7773.t68 cds g7773.t68.CDS4 25897723 25898178
chr_2 g7773 g7773.t68 exon g7773.t68.exon5 25898246 25898302
chr_2 g7773 g7773.t68 cds g7773.t68.CDS5 25898246 25898302
chr_2 g7773 g7773.t68 TSS g7773.t68 NA NA
chr_2 g7773 g7773.t68 TTS g7773.t68 NA NA

Sequences

>g7773.t68 Gene=g7773 Length=2134
ATGGACAGTTATACAAAAAAATCAGGATCTACTGATTCATTAAATAATGACACAGTTCTC
CCAAAAGAACTTCCATTTCAATTGCTATCGGGTGAAACATTTCAAGAGAAAAATGAAGTG
TCCTATATTTGTCCATATTTTGGTCCAATTCGAGGAATTCTTTACATAACAAATTATCGT
CTGTATTTTAAATCATCAATTGACAAAGATCCAGTACAACAAAATTTAGATGTAAATTTG
GGCGTTGTATCGAGAATTGAGAAAGTTGGTGGTGCTAGCTCTCGTGGTGAAAACTCATAT
GGTATTGATATTTTATGCAAGGATATGAGAAATTTGAGATTTGCACACAAACAAGAAAAT
CATTCTCGTCGCACAGTTTTTGGAAAACTGCAGAATTTTGCATTCCCTTTAGCAAATAAT
GAAAAGCTCTTTGCGTTCAACTATTCAGAAAAATTTCCTGAGGATGGATGGAATGTTTAT
GAGCCTATTGCTGAATTTCGTCGCATGGGATTAGGAGCAAATTCAAATATTGAATGGCGT
GTAACAAAAGTTAATCAAGCATATGAATTATGTGACAGTTATCCAGCTGTATTAGCAGTT
CCTCGCAGTATTTCTGATGAAGATTTAAAAGCTGTTGCAAACTTCCGTTCAAGAAATCGT
TTGCCAGTATTATCATGGATTCATCCACAATCATTAGCAACTATAACAAGATGCTCACAA
CCTCTGTGTGGAGTAAGTGGAAAAAAGTCATCAGAAGATGAAGGTTATATAAATGCAATA
ATGGAAGCAAATCCCTTATCACATAAACTCATTATCATGGATGCTCGTCCTTCAGCGAAT
GCGGTTGTGAATAAAGCAAAAGGAGGCGGTTATGAATCAGAGAATGACTATCAAAATGTT
GAATTGATTTTCTTAGATATTCACAATATTCATGTAATGCGTGAAAGTTTAAGAAAACTC
AAAGAAATTTGCTTTCCTGCAACTGATGATCAAAAATGGCTTTCATCTGTTGATAATACA
ATGTGGCTTAAGCATATCAAATGTGTACTTGCTGGTGCCATTCGAATTGTTGATCGTATT
GAAAATACTAAAAATTCTGTAGTGGTTCATTGTTCTGATGGATGGGATAGAACTGCACAA
TTGACTGCTTTAGCAATGATTATGTTGGATCCATATTATAGGACAATAAAAGGTTTTGAA
GTGCTAATAGAAAAAGAATGGCTTAGTTTTGGACATAAATTCCAACAACGTATTGGACAT
GGTGACATCAATCATTCAGATGCAGATCGTTCACCAGTTTTTGTTCAATTTATTGACTGT
GTGTGGCAAATTACAAGACAACTGCCAAACTCTTTTGAGTTTAATGAAAATTTCCTCATT
ACAATTCTTGATCATCTATATTCATGTCGATTCGGTACATTTTTATGTAACACAGAACGT
GAGCGGGTAAATGAGGTGAAGAAATATACAGTTTCATTATGGTCATACATAAATGCATCA
CTTGAACTCTACAGAAATCCACTTTATGGTGGATTCGGTAATTCTCCGACTCTACAAACA
GTTTTAAAACCTGTTGCAAGTATGAGACATATAAGATTATGGAAAGGTTATTATTGTCGT
TGGAATCCAACAATGAAAACGCAAGAACCAATTTATCAGCGAACAAGAGAACTCCTTGCA
TTGCAAGATCAATTAAGAAAACAAATTGACGAAATTCTCGAATGTCGCACTGATGGCAAT
CTATCGACAAACTTTATTTAAAAAATTAGATAGAATTCATTTATTGTCAAATTTACACAT
ATTTAAGCACCATTCATTCATTAATATTTTATCAAATCAATCAACTTTTTTGACTTTACA
TTATTTTACATGTAGAGATTTATTGAATGAATTTGTTCCTTGCAAGTCTTAAACTTAATC
CTGTTGTATCTGGAAGTATAGAAGTGAACGCAATTGCTCCGCCAATAATCATAATTACAC
CAAATATACTAATAAAATGCATAATAGAAATATTTTTAAAATAGAAATAAGAGACAATTA
AGAGAATTTGTATGGAACATTCAATAATATTGGTCATTGCAATAAAGAAAGGTTTAACTC
GCGTATTAACGCTATCGACTAAGAAAATATCAGA

>g7773.t68 Gene=g7773 Length=586
MDSYTKKSGSTDSLNNDTVLPKELPFQLLSGETFQEKNEVSYICPYFGPIRGILYITNYR
LYFKSSIDKDPVQQNLDVNLGVVSRIEKVGGASSRGENSYGIDILCKDMRNLRFAHKQEN
HSRRTVFGKLQNFAFPLANNEKLFAFNYSEKFPEDGWNVYEPIAEFRRMGLGANSNIEWR
VTKVNQAYELCDSYPAVLAVPRSISDEDLKAVANFRSRNRLPVLSWIHPQSLATITRCSQ
PLCGVSGKKSSEDEGYINAIMEANPLSHKLIIMDARPSANAVVNKAKGGGYESENDYQNV
ELIFLDIHNIHVMRESLRKLKEICFPATDDQKWLSSVDNTMWLKHIKCVLAGAIRIVDRI
ENTKNSVVVHCSDGWDRTAQLTALAMIMLDPYYRTIKGFEVLIEKEWLSFGHKFQQRIGH
GDINHSDADRSPVFVQFIDCVWQITRQLPNSFEFNENFLITILDHLYSCRFGTFLCNTER
ERVNEVKKYTVSLWSYINASLELYRNPLYGGFGNSPTLQTVLKPVASMRHIRLWKGYYCR
WNPTMKTQEPIYQRTRELLALQDQLRKQIDEILECRTDGNLSTNFI

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g7773.t68 CDD cd14535 PTP-MTM1-like 219 467 0.0
8 g7773.t68 Gene3D G3DSA:2.30.29.30 - 34 134 3.9E-41
7 g7773.t68 Gene3D G3DSA:3.90.190.10 Protein tyrosine phosphatase superfamily 313 442 3.2E-5
3 g7773.t68 PANTHER PTHR10807:SF42 MYOTUBULARIN-RELATED PROTEIN 2 25 572 7.8E-270
4 g7773.t68 PANTHER PTHR10807 MYOTUBULARIN-RELATED 25 572 7.8E-270
1 g7773.t68 Pfam PF02893 GRAM domain 26 136 5.1E-18
2 g7773.t68 Pfam PF06602 Myotubularin-like phosphatase domain 143 482 3.8E-153
10 g7773.t68 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 369 379 -
13 g7773.t68 ProSiteProfiles PS51339 Myotubularin phosphatase domain. 156 538 129.661
11 g7773.t68 SMART SM00568 gram2001c 22 90 1.1E-10
12 g7773.t68 SMART SM00404 ptp_7 328 467 1.3E-4
5 g7773.t68 SUPERFAMILY SSF50729 PH domain-like 26 148 1.84E-36
6 g7773.t68 SUPERFAMILY SSF52799 (Phosphotyrosine protein) phosphatases II 151 543 1.44E-151

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016311 dephosphorylation BP
GO:0004725 protein tyrosine phosphatase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed