Gene loci information

Transcript annotation

  • This transcript has been annotated as Myotubularin-related protein 2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7773 g7773.t69 isoform g7773.t69 25897307 25898302
chr_2 g7773 g7773.t69 exon g7773.t69.exon1 25897307 25897664
chr_2 g7773 g7773.t69 cds g7773.t69.CDS1 25897308 25897664
chr_2 g7773 g7773.t69 exon g7773.t69.exon2 25897723 25898178
chr_2 g7773 g7773.t69 cds g7773.t69.CDS2 25897723 25898178
chr_2 g7773 g7773.t69 exon g7773.t69.exon3 25898246 25898302
chr_2 g7773 g7773.t69 cds g7773.t69.CDS3 25898246 25898302
chr_2 g7773 g7773.t69 TSS g7773.t69 NA NA
chr_2 g7773 g7773.t69 TTS g7773.t69 NA NA

Sequences

>g7773.t69 Gene=g7773 Length=871
ATGGACAGTTATACAAAAAAATCAGGATCTACTGATTCATTAAATAATGACACAGTTCTC
CCAAAAGAACTTCCATTTCAATTGCTATCGGGTGAAACATTTCAAGAGAAAAATGAAGTG
TCCTATATTTGTCCATATTTTGGTCCAATTCGAGGAATTCTTTACATAACAAATTATCGT
CTGTATTTTAAATCATCAATTGACAAAGATCCAGTACAACAAAATTTAGATGTAAATTTG
GGCGTTGTATCGAGAATTGAGAAAGTTGGTGGTGCTAGCTCTCGTGGTGAAAACTCATAT
GGTATTGATATTTTATGCAAGGATATGAGAAATTTGAGATTTGCACACAAACAAGAAAAT
CATTCTCGTCGCACAGTTTTTGGAAAACTGCAGAATTTTGCATTCCCTTTAGCAAATAAT
GAAAAGCTCTTTGCGTTCAACTATTCAGAAAAATTTCCTGAGGATGGATGGAATGTTTAT
GAGCCTATTGCTGAATTTCGTCGCATGGGATTAGGAGCAAATTCAAATATTGAATGGCGT
GTAACAAAAGTTAATCAAGCATATGAATTATGTGACAGTTATCCAGCTGTATTAGCAGTT
CCTCGCAGTATTTCTGATGAAGATTTAAAAGCTGTTGCAAACTTCCGTTCAAGAAATCGT
TTGCCAGTATTATCATGGATTCATCCACAATCATTAGCAACTATAACAAGATGCTCACAA
CCTCTGTGTGGAGTAAGTGGAAAAAAGTCATCAGAAGATGAAGGTTATATAAATGCAATA
ATGGAAGCAAATCCCTTATCACATAAACTCATTATCATGGATGCTCGTCCTTCAGCGAAT
GCGGTTGTGAATAAAGCAAAAGGAGGCGGTT

>g7773.t69 Gene=g7773 Length=290
MDSYTKKSGSTDSLNNDTVLPKELPFQLLSGETFQEKNEVSYICPYFGPIRGILYITNYR
LYFKSSIDKDPVQQNLDVNLGVVSRIEKVGGASSRGENSYGIDILCKDMRNLRFAHKQEN
HSRRTVFGKLQNFAFPLANNEKLFAFNYSEKFPEDGWNVYEPIAEFRRMGLGANSNIEWR
VTKVNQAYELCDSYPAVLAVPRSISDEDLKAVANFRSRNRLPVLSWIHPQSLATITRCSQ
PLCGVSGKKSSEDEGYINAIMEANPLSHKLIIMDARPSANAVVNKAKGGG

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g7773.t69 Gene3D G3DSA:2.30.29.30 - 34 134 0.000
3 g7773.t69 PANTHER PTHR10807:SF42 MYOTUBULARIN-RELATED PROTEIN 2 25 290 0.000
4 g7773.t69 PANTHER PTHR10807 MYOTUBULARIN-RELATED 25 290 0.000
1 g7773.t69 Pfam PF02893 GRAM domain 26 136 0.000
2 g7773.t69 Pfam PF06602 Myotubularin-like phosphatase domain 143 290 0.000
9 g7773.t69 ProSiteProfiles PS51339 Myotubularin phosphatase domain. 156 290 42.456
7 g7773.t69 SMART SM00568 gram2001c 22 90 0.000
5 g7773.t69 SUPERFAMILY SSF50729 PH domain-like 26 148 0.000
6 g7773.t69 SUPERFAMILY SSF52799 (Phosphotyrosine protein) phosphatases II 151 290 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

There are no GO annotations for this transcript.

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values