Gene loci information

Transcript annotation

  • This transcript has been annotated as Zinc finger FYVE domain-containing protein 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7853 g7853.t10 TTS g7853.t10 26418557 26418557
chr_2 g7853 g7853.t10 isoform g7853.t10 26418877 26421463
chr_2 g7853 g7853.t10 exon g7853.t10.exon1 26418877 26419008
chr_2 g7853 g7853.t10 exon g7853.t10.exon2 26419073 26419365
chr_2 g7853 g7853.t10 cds g7853.t10.CDS1 26419353 26419365
chr_2 g7853 g7853.t10 exon g7853.t10.exon3 26419483 26419607
chr_2 g7853 g7853.t10 cds g7853.t10.CDS2 26419483 26419607
chr_2 g7853 g7853.t10 exon g7853.t10.exon4 26419674 26421236
chr_2 g7853 g7853.t10 cds g7853.t10.CDS3 26419674 26421236
chr_2 g7853 g7853.t10 exon g7853.t10.exon5 26421461 26421463
chr_2 g7853 g7853.t10 cds g7853.t10.CDS4 26421461 26421463
chr_2 g7853 g7853.t10 TSS g7853.t10 26421541 26421541

Sequences

>g7853.t10 Gene=g7853 Length=2116
ATGGACACAATTTCATCGCCTATCTATGTGTCGCGCGCGGAATCGAAGCCAGATTTGTTG
AATGTCAGCAAGGAAATCGAGGATGCCCTGCACAGTATAAATCTCAATAGTCAAACATAT
GACACCAATGATCCGCACAGTAAATCCTTTGCCATTATAGACTCAAATGAAAATTTTCAA
GTTAGCAGTTTGGAAAATTTTACAAAAAAACTTGGCATAGGCGATTGTGAAAAGAAGGTG
AAGGTTGTGTCAATTTTTGGGAACTCAGGTGATGGAAAATCGCACACACTCAATAATGTG
TTCTTTGATGGCTATGAAATATTCAAAATGAGTTCCGAGCAAAAGTCATGCACATTAGGT
GTATGGCTTGCGTATCAAGGATATTTTTATAACAGTCCAATTCTATGTGTCGATACAGAA
GGACTTCAGGGAGTAGCACAAAATGAAAATCAACAGCATCGAATGCTTATGAAGGTACTT
GCCGTATCTGATATTATTATTTATCGAACACGAGCAGAACGACTAAACTCAGATATGTAC
AAATTTCTTGGAACAGCATCGAAAATATATCAACGTCATCTTAGTCCACTTTTAAATGAC
AACGCATCAAATTTTACAACATACGGTCCATCAGTGATAATTTTTCATGAAGTTTCAAAT
ACATGGCCATTAGAGACGAGCATAGTCGAGTCACCTGAAAATATAATCAAGGAAAAATTC
TCTGAGATGAAATTAAATATTGACGCATTTAGTTCACTCAAATATGTCGGCATCAAAACA
AGTTCTGCACCAACTGATTTTAATCCATTGAAAAGCATTTTGAAAAATGATATTGAAAAT
AAAGGAAAACATATGAGAAGCATAAGAAGCATTTATGATCAGCTTGAGATGCTTAACAAT
AAATTTTCCGGTGATGTCGAGTATAACATTGATAAAGAATATACTTTGCATGAATCACAT
TTTAAGTGCGAAGTGACATGTGAAGGATGCTTTCAGCGCTGTGAAAACACTCGTGATCAT
ATTAAGGACGGTCAGGAACATAGCAATTCCGCCGCATGCATCTATCAGCAACAGCTTAAT
AATAAGATTTATCTATGCAAGCGATGTCATCTAGAAAATCGCAGAAGTGTTGTAAAAATA
AATAATGCGAATGGTGATTGGCTAACTAAATACACGTGGGGTATCGGAGCTAATTCAAAA
ATCGATTGTGTTCGTCATGGTGAGATTTATCGCAGTCGATGGTATGGTAACAAAAATCCT
GAAGAAATTTGCGTTCTTTCTGAGGCCGTTCACATTTGGCGTGACGGCTTATCAAGAAAT
CAAGTGCCAACACATTCTGCACAAGCCATTGTTGATGGATTTTCATACATTTCCGATGCT
ATTTCATCAGTTTCTGCACAACCAACAAAGACTGTGACGTCATGGGTAGCAGATAATTTA
GTTAATCCTACATATTGGGTTCCAAATTCTGAAATTATCCATTGTGAGCTATGTAAGACG
AATTTCGAATCGAGTGGATTAAAAATTCATCATTGTCGCAATTGTGGAAAAGGTGTATGC
AATGATTGTTCAAAGAACAGAATGAAAGTTCCACTTAAACTTGGATGGGGATATGATCTC
GTAAGAGTATGCAATCGATGCAGAGATGAATTAATGAAAAATGAAAATGGTAATAATAAT
GATGCAGGTTCAACGTTTCGATGAAAAAACAAAGAATGTGAAAGTGCGAAAATATGGTGA
AGTGATTTTTAATGCAGTTAGCACTGTTGCAGCGGCTTTAGAATATCCTAAAGAACTAAT
TAAAGACAGTGTACGACCTGAATACTGGGCTCGTGATAGCGAGTCACCATCATGTTCATT
GTGTGATCAAGTATTTGGTAATCTTGACGATATGGAGCAATCTAAAATTCGTGAATTGAG
TAGCGCTTCAGGAAATTCATTGGGAAATTCACCAAATCATGTTATTGATATTCGACGACA
TCACTGTCGTGGATGTGGTGCAGCTGTGTGTAATAAATGTTCTACAAATCGAAGACCTGT
TCCTGAAAGAGGATGGAACAATGAAGTTCGAGTTTGTGATAACTGCTGGAAGAAACCAAA
TGCAAAGGACTCATAA

>g7853.t10 Gene=g7853 Length=567
MDTISSPIYVSRAESKPDLLNVSKEIEDALHSINLNSQTYDTNDPHSKSFAIIDSNENFQ
VSSLENFTKKLGIGDCEKKVKVVSIFGNSGDGKSHTLNNVFFDGYEIFKMSSEQKSCTLG
VWLAYQGYFYNSPILCVDTEGLQGVAQNENQQHRMLMKVLAVSDIIIYRTRAERLNSDMY
KFLGTASKIYQRHLSPLLNDNASNFTTYGPSVIIFHEVSNTWPLETSIVESPENIIKEKF
SEMKLNIDAFSSLKYVGIKTSSAPTDFNPLKSILKNDIENKGKHMRSIRSIYDQLEMLNN
KFSGDVEYNIDKEYTLHESHFKCEVTCEGCFQRCENTRDHIKDGQEHSNSAACIYQQQLN
NKIYLCKRCHLENRRSVVKINNANGDWLTKYTWGIGANSKIDCVRHGEIYRSRWYGNKNP
EEICVLSEAVHIWRDGLSRNQVPTHSAQAIVDGFSYISDAISSVSAQPTKTVTSWVADNL
VNPTYWVPNSEIIHCELCKTNFESSGLKIHHCRNCGKGVCNDCSKNRMKVPLKLGWGYDL
VRVCNRCRDELMKNENGNNNDAGSTFR

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g7853.t10 Gene3D G3DSA:3.40.50.300 - 45 253 0.00000
9 g7853.t10 Gene3D G3DSA:3.30.40.10 Zinc/RING finger domain 475 557 0.00000
3 g7853.t10 PANTHER PTHR46624:SF1 AGAP002036-PA 44 560 0.00000
4 g7853.t10 PANTHER PTHR46624 AGAP002036-PA 44 560 0.00000
1 g7853.t10 Pfam PF02263 Guanylate-binding protein, N-terminal domain 76 170 0.00015
2 g7853.t10 Pfam PF01363 FYVE zinc finger 485 552 0.00000
10 g7853.t10 ProSiteProfiles PS50178 Zinc finger FYVE/FYVE-related type profile. 489 552 11.28300
7 g7853.t10 SMART SM00064 fyve_4 481 553 0.00000
5 g7853.t10 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 50 194 0.00000
6 g7853.t10 SUPERFAMILY SSF57903 FYVE/PHD zinc finger 459 551 0.00000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0046872 metal ion binding MF
GO:0005525 GTP binding MF
GO:0003924 GTPase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed