Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Folate transporter 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7901 g7901.t1 isoform g7901.t1 26930820 26932248
chr_2 g7901 g7901.t1 exon g7901.t1.exon1 26930820 26931314
chr_2 g7901 g7901.t1 cds g7901.t1.CDS1 26930820 26931314
chr_2 g7901 g7901.t1 exon g7901.t1.exon2 26931377 26931612
chr_2 g7901 g7901.t1 cds g7901.t1.CDS2 26931377 26931612
chr_2 g7901 g7901.t1 exon g7901.t1.exon3 26931729 26932248
chr_2 g7901 g7901.t1 cds g7901.t1.CDS3 26931729 26932248
chr_2 g7901 g7901.t1 TSS g7901.t1 26932297 26932297
chr_2 g7901 g7901.t1 TTS g7901.t1 NA NA

Sequences

>g7901.t1 Gene=g7901 Length=1251
ATGCAAAATTATCTCAAAATATCATTTGCATTGAGTGCATTTGGATTTTTAAAAGAAACT
CGACTAATTGAACCATTTTTAACTGATTATTACACATCATATGATGGCGTCACAGAGGAA
GTAATAAACAGAGAAATCTTCCCAGTTGGAACTTATTCGCATATGATTCAACTTCTGATA
ATTTTCTTAATCACCGATTATCTAAGATACAAGCCACTTATTATTGTTCTTGGATTATCT
AGTGTCTCAATATGGGGGATCATGCTGCTAGTTAAAGCAAAACTTGGATTGCAAATAATT
GAAGTAATTTATGGAACATTTTGTGCTTGTGAAGTTGCTTATTATAGTTATATTTATGCA
AAAACTGATAAACAACATTATCAAATTGTAACATCACATACAAGAGCTGCAGTTTTATTA
GGAAAATTCTTTTCAGCTACACTTTCGCAACTCATCGTTTATTTCTTTCATGACGCTGAT
AACATTAATTATCGACAGCTTAACTTCATCACATTTATCTTTCAAGTAGTAACAGCAATT
TGGAGCATTTTCTTTATACCATCTGTTAATAGAAGCATTTATTTTCATTGTAAAGAGATT
GAAAATGTTGAGTCCACAAAGCAATCATTTTCAAGTGCATTTATGCTAATTTGGGAACAT
TTCAAGACTTCTTATAGAAATGAGACTGTGCTTTTATGGTGCATTTTTTATGCATTTTCT
TTCTGTCTCTACTTTCAAATTACCGCATACATTCAGATTTTATGGCTAGCCATTGATGAG
TATGTGTTCTGGAATGCAACCGTTGATGGTTGTCTAACTTTACTTAGTGCCATTGCAATG
TTAATTGCTGGAAAAATTCAAATTTCTTTCTTGAAAAAGCAAAGTACCACAATGATAGTT
TTAATTTTAATGTCATTGCTTCAAGGAGTTTTCATGTTTTTTGCGGCAACAGCTCTGACA
CTTTTAACTTGTTACATTTTCTACATTCTCAATGGTATTGCATATGGTTTCAGCATCACA
ATTTGTGCAACGAAAATTGCCGAAAATATTGCTGAAGATTCGCATGGATTAGTTTTTGGA
TTTAATACTTTTATTGCACTTTGTATTCAAACATGCCTCACTTTAGCCATTGTATCGAGT
GGATTTAAATTGCCTGCAGTCGGTCAATTTATTGTGTACAGTGTAATGTATTTTATCTTG
GGATTTTTTTTTCTTGTTAAATTTCTAATTGATTGGTGCAGATCAAGATAA

>g7901.t1 Gene=g7901 Length=416
MQNYLKISFALSAFGFLKETRLIEPFLTDYYTSYDGVTEEVINREIFPVGTYSHMIQLLI
IFLITDYLRYKPLIIVLGLSSVSIWGIMLLVKAKLGLQIIEVIYGTFCACEVAYYSYIYA
KTDKQHYQIVTSHTRAAVLLGKFFSATLSQLIVYFFHDADNINYRQLNFITFIFQVVTAI
WSIFFIPSVNRSIYFHCKEIENVESTKQSFSSAFMLIWEHFKTSYRNETVLLWCIFYAFS
FCLYFQITAYIQILWLAIDEYVFWNATVDGCLTLLSAIAMLIAGKIQISFLKKQSTTMIV
LILMSLLQGVFMFFAATALTLLTCYIFYILNGIAYGFSITICATKIAENIAEDSHGLVFG
FNTFIALCIQTCLTLAIVSSGFKLPAVGQFIVYSVMYFILGFFFLVKFLIDWCRSR

Protein features from InterProScan

Transcript Database ID Name Start End E.value
14 g7901.t1 Gene3D G3DSA:1.20.1250.20 MFS general substrate transporter like domains 5 410 1.3E-15
2 g7901.t1 PANTHER PTHR10686 FOLATE TRANSPORTER 3 415 1.8E-106
1 g7901.t1 Pfam PF01770 Reduced folate carrier 3 392 1.2E-106
28 g7901.t1 Phobius SIGNAL_PEPTIDE Signal peptide region 1 22 -
29 g7901.t1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 6 -
30 g7901.t1 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 7 17 -
42 g7901.t1 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 18 22 -
23 g7901.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 23 45 -
32 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 46 65 -
17 g7901.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 66 71 -
40 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 72 91 -
27 g7901.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 92 96 -
35 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 97 117 -
21 g7901.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 118 136 -
34 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 137 157 -
25 g7901.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 158 168 -
41 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 169 189 -
16 g7901.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 190 229 -
33 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 230 255 -
22 g7901.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 256 260 -
31 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 261 284 -
20 g7901.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 285 295 -
38 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 296 319 -
24 g7901.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 320 324 -
37 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 325 344 -
18 g7901.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 345 355 -
36 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 356 378 -
26 g7901.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 379 389 -
39 g7901.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 390 410 -
19 g7901.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 411 416 -
13 g7901.t1 SUPERFAMILY SSF103473 MFS general substrate transporter 20 406 2.75E-19
15 g7901.t1 TIGRFAM TIGR00806 rfc: reduced folate carrier 7 410 2.1E-77
11 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 72 91 -
6 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 96 118 -
4 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 138 157 -
3 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 167 189 -
12 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 230 252 -
5 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 262 284 -
10 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 297 319 -
7 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 324 343 -
9 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 356 378 -
8 g7901.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 388 410 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0090482 vitamin transmembrane transporter activity MF
GO:0051180 vitamin transport BP
GO:0016021 integral component of membrane CC

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed