General information for g7920.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Inositol polyphosphate 5-phosphatase E.
Parent gene
- The parent gene g7920 is located on chr_2: 27069363..27070345 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7920 | g7920.t1 | TSS | g7920.t1 | 27066987 | 27066987 |
| chr_2 | g7920 | g7920.t1 | isoform | g7920.t1 | 27067340 | 27069363 |
| chr_2 | g7920 | g7920.t1 | exon | g7920.t1.exon1 | 27067340 | 27068820 |
| chr_2 | g7920 | g7920.t1 | cds | g7920.t1.CDS1 | 27067340 | 27068820 |
| chr_2 | g7920 | g7920.t1 | exon | g7920.t1.exon2 | 27068877 | 27069206 |
| chr_2 | g7920 | g7920.t1 | cds | g7920.t1.CDS2 | 27068877 | 27069206 |
| chr_2 | g7920 | g7920.t1 | exon | g7920.t1.exon3 | 27069258 | 27069363 |
| chr_2 | g7920 | g7920.t1 | cds | g7920.t1.CDS3 | 27069258 | 27069363 |
| chr_2 | g7920 | g7920.t1 | TTS | g7920.t1 | 27070342 | 27070342 |
Sequences
>g7920.t1 Gene=g7920 Length=1917
ATGAGCGAGGAGGCAGCAAATCAAGTCGTACGAAGGAACAAACAGCAAATTCTAGGATTT
CTTGGTGTTCGAAGATCAACAAAGGTTGAACCACAAAATAATAGCAATAATAACAATACA
AGCTCTGATGACTCCATTTCGCGACAACCAATAGGTCAAATACGCCAAATTAATGTAAAG
AGCAAAAAGGTCATGGAAAGAAATAATTCTGTTCCTGATTTGAGTAAGAATGAATTAGAA
ATAAGTAACTATAATGCTAAAAGCAACACTAATCGATACAGTTATTGCTGTACCTCAACA
AGCAATGGAATATTCAATTCAGATTCGGGAATTGAAAATGCAGCTAGTAATGATGAAGAA
ACATCGCCTCTATTAATTCCATCATCCTCACGTCCTCTTGGTGTCCATAGTTCAGCAGTC
AATGTTCAATATAATCTTCCAAAATATGAAGCCTATCCATCGCCCATTCTTCTCTCATGC
CGCTCTAGATTTCGTGAAAAATTCTTACCTCCTTCATTAGAACAGTATAATACCCTCAAG
GACTGTAATTCATCACCAAATATTCCAGTACATAATGCTAGTTCTTCATCAGCAACCAAT
AGCGATGAACGCAAATCGGGATCATTTGATACAATTTCAATGGTTGATCGACAAAAAATT
GAAGACTGCTGTTCTGATCCAGAACGAGTCAGTGCAGATTCACTTGCTCGTCAAGCGCTA
GTTGCTGCTCAAGTTTTGCATCTTATTCCAACTGAAAAAGCGCGGCAAAGAAATTTTTTG
CAAGGCAGGTCAGCTTCAATTTCACTTTTAGGTGCAACTGAACTTGAAAAGACATTTCCC
AATAGAACAGCGACAATTTTTGTTGGTAGTTGGAACATGAATGGCAGAAATGATATCCCT
AAACAAATGAATGACTTTCTTTTGCCAAATTCAATTGAACATATTCCAGATTTGGTTGTT
ATCGGCACACAAGAAGCATGCTCCGATAAATTTGAATGGGAAGTAACTTTGCAAGAAACA
CTTGGGCCATCACATGTGCTCTTTCATTCAGCTAGTTTGGGAACATTACATTTGGCAGTA
TTTATGCGTCGTGATTTAATTTGGTATTGCTCAGAGCCGGAGGATGCCTCGTTATCTGTT
CGACCAGGCTCACATTTTAAAACTAAAGGTGCTGTAGCTATTTCATTTTGCTTATTTGGG
ACTTCAATGCTTTTCGTTACTAGTCATTTGACTGCTCATCAACAAAAAGTCAAAGAAAGA
GTTCAAGACATAAAAAGAATTATTCATGCTCTTGATTTACCGAGAAATTTGAATGTCAGA
CACCGTGCAAAGGATGTAACTCAAAACTTTGATTCTGTTTATTGGTGCGGTGATTTAAAC
TTCAGACTGAGTGAACCAAGAGATAATTTATTGAAATGGATTAACGAGACTCAATTTCCA
TTGCCAAGTCATCTTCCTCATGGATTTCTTCATACTGATCAATTAACATCAGTATTAGCA
GATGGTGCAGCATTCAAAGGATTTAAAGAAGCAAAAATTCATTTTCCACCAACTTACAAA
TATGATGTTGGTACACAACAGTTTGATACATCTTCAAAGCAGCGAGCACCGGCCTACACT
GACCGAATATTATACAAACATAAATTGCCACCGCTTGGTCTTCGTCGACAGAGTGCGATG
CCTGGAAGTTCATTACAACCATCATCACCAATTAAATGTATTGCCTATGATTCTGTTCAG
AGTATTGTATCATCTGATCATAAACCCGTTTGGGCACTTTTTAAAAATGCTTTGCGACCT
GGTGCTGATTCAATTCCACTAGCAGCAAGTTTCAATCGAGAAGTATATATTGAAGGTATT
AAACACAGATTGGACAACAATTTGGCAGGATCAACTTCAGCATGCATCATACAGTAA
>g7920.t1 Gene=g7920 Length=638
MSEEAANQVVRRNKQQILGFLGVRRSTKVEPQNNSNNNNTSSDDSISRQPIGQIRQINVK
SKKVMERNNSVPDLSKNELEISNYNAKSNTNRYSYCCTSTSNGIFNSDSGIENAASNDEE
TSPLLIPSSSRPLGVHSSAVNVQYNLPKYEAYPSPILLSCRSRFREKFLPPSLEQYNTLK
DCNSSPNIPVHNASSSSATNSDERKSGSFDTISMVDRQKIEDCCSDPERVSADSLARQAL
VAAQVLHLIPTEKARQRNFLQGRSASISLLGATELEKTFPNRTATIFVGSWNMNGRNDIP
KQMNDFLLPNSIEHIPDLVVIGTQEACSDKFEWEVTLQETLGPSHVLFHSASLGTLHLAV
FMRRDLIWYCSEPEDASLSVRPGSHFKTKGAVAISFCLFGTSMLFVTSHLTAHQQKVKER
VQDIKRIIHALDLPRNLNVRHRAKDVTQNFDSVYWCGDLNFRLSEPRDNLLKWINETQFP
LPSHLPHGFLHTDQLTSVLADGAAFKGFKEAKIHFPPTYKYDVGTQQFDTSSKQRAPAYT
DRILYKHKLPPLGLRRQSAMPGSSLQPSSPIKCIAYDSVQSIVSSDHKPVWALFKNALRP
GADSIPLAASFNREVYIEGIKHRLDNNLAGSTSACIIQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g7920.t1 | Gene3D | G3DSA:3.60.10.10 | - | 261 | 630 | 3.5E-115 |
| 6 | g7920.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 21 | 51 | - |
| 5 | g7920.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 27 | 51 | - |
| 7 | g7920.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 190 | 211 | - |
| 2 | g7920.t1 | PANTHER | PTHR47039 | INOSITOL POLYPHOSPHATE 5-PHOSPHATASE E | 178 | 638 | 6.4E-197 |
| 1 | g7920.t1 | Pfam | PF03372 | Endonuclease/Exonuclease/phosphatase family | 289 | 587 | 1.6E-6 |
| 10 | g7920.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 390 | - |
| 11 | g7920.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 391 | 412 | - |
| 9 | g7920.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 413 | 638 | - |
| 4 | g7920.t1 | SMART | SM00128 | i5p_5 | 282 | 602 | 8.7E-52 |
| 3 | g7920.t1 | SUPERFAMILY | SSF56219 | DNase I-like | 280 | 597 | 3.6E-53 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0046856 | phosphatidylinositol dephosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K20278 (inositol polyphosphate 5-phosphatase INPP5E)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
