Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Retinoblastoma-like protein 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8044 g8044.t3 isoform g8044.t3 28203930 28204728
chr_2 g8044 g8044.t3 exon g8044.t3.exon1 28203930 28203995
chr_2 g8044 g8044.t3 cds g8044.t3.CDS1 28203933 28203995
chr_2 g8044 g8044.t3 exon g8044.t3.exon2 28204063 28204509
chr_2 g8044 g8044.t3 cds g8044.t3.CDS2 28204063 28204509
chr_2 g8044 g8044.t3 exon g8044.t3.exon3 28204567 28204728
chr_2 g8044 g8044.t3 cds g8044.t3.CDS3 28204567 28204728
chr_2 g8044 g8044.t3 TSS g8044.t3 NA NA
chr_2 g8044 g8044.t3 TTS g8044.t3 NA NA

Sequences

>g8044.t3 Gene=g8044 Length=675
TTAATGAAAGATCGTCATTTAGATCAAATTTTGATGTGTTGTGTTTATGTCCTTTGTAAG
ATTAGGCCAAATGAAAATCGTCACACATTTGCAGACATCATGAAGTTTTACAGAAATCAG
CCACAATCTGACTCGCATATCTATCGTAGTGTCTTCATAGAATATGTTCAAACGGATAAA
GCTAATGAGATGCAAGAACCGAAGGCAAGTGCTGCTGAGCCAGAAGTCGTTAATGGTAGA
AACACTATATATGGAACTGAAAGTCGAGGAGACATCATTTATTTTTACAACAAAATATTT
GTTCCAAAAATGCAACAATTTGCGATGAGATTTTCAACTTCTTCACAAAATAATCTTCTT
CTATCACCATTGCCACAGTCACGTCCTCTGATCTCACCTAGAAAAAAAATTTCACCTTAT
CATGATGTATATGTACAACCGTTGACAAAACAAAGCATTCTTTCACCTTCAGCACGTACT
CTTACTTTTACAATTGAACAAAGCCCCTCAAAGGATCTCCAGAAAATAAATTCCATGATT
AATCAGAATAAGAAGGCAAGCGTTGCAAAGCGTTTTATGATGGATACTGAAGATGATTTC
CGTCCTGCAAAAGTTTCAAAGGACTCTTCTTTACAACTTCGACTTTTAATTGACCGTGAA
GAGATTAGCAATTAG

>g8044.t3 Gene=g8044 Length=223
MKDRHLDQILMCCVYVLCKIRPNENRHTFADIMKFYRNQPQSDSHIYRSVFIEYVQTDKA
NEMQEPKASAAEPEVVNGRNTIYGTESRGDIIYFYNKIFVPKMQQFAMRFSTSSQNNLLL
SPLPQSRPLISPRKKISPYHDVYVQPLTKQSILSPSARTLTFTIEQSPSKDLQKINSMIN
QNKKASVAKRFMMDTEDDFRPAKVSKDSSLQLRLLIDREEISN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
4 g8044.t3 Gene3D G3DSA:1.10.472.10 - 1 128 0
2 g8044.t3 PANTHER PTHR13742 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED 1 198 0
1 g8044.t3 Pfam PF01857 Retinoblastoma-associated protein B domain 1 104 0
3 g8044.t3 SUPERFAMILY SSF47954 Cyclin-like 1 125 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006357 regulation of transcription by RNA polymerase II BP
GO:0005634 nucleus CC
GO:0051726 regulation of cell cycle BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values